Mô hình hóa phân bố trường điện trong các mô trong quá trình thẩm điện
Tóm tắt
Các liệu pháp và điều trị dựa trên thẩm điện (ví dụ: hóa trị điện, chuyển giao gen qua điện cho liệu pháp gen và tiêm vắc xin DNA, tiêu hủy mô bằng thẩm điện không thể đảo ngược và truyền thuốc qua da) yêu cầu dự đoán chính xác kết quả điều trị thông qua quy trình lập kế hoạch điều trị cá nhân hóa. Mô hình số hóa phân bố trường điện cục bộ trong các mô được thẩm điện đã trở thành một công cụ quan trọng trong quy trình lập kế hoạch điều trị cả trong lâm sàng và thí nghiệm. Các nghiên cứu gần đây đã báo cáo rằng những bất định trong tính chất điện (tức là độ dẫn điện của các mô được điều trị và tốc độ tăng độ dẫn điện do thẩm điện) được xác định trong các mô hình số có ảnh hưởng lớn đến hiệu quả điều trị dựa trên thẩm điện. Mục tiêu của nghiên cứu của chúng tôi là điều tra xem việc tăng độ dẫn điện của các mô có cần được xem xét khi mô hình hóa phản ứng mô đối với xung thẩm điện và nó ảnh hưởng như thế nào đến phân bố điện cục bộ trong các mô bị thẩm điện.
Từ khóa
#Tính dẫn điện #Thẩm điện #Lập mô hình số #Phân bố trường điện #Điều trị cá nhân hóaTài liệu tham khảo
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