Mitochondrial diversity in European and Chinese pigs is consistent with population expansions that occurred prior to domestication

Proceedings of the Royal Society B: Biological Sciences - Tập 273 Số 1595 - Trang 1803-1810 - 2006
Meiying Fang1,2, Leif Andersson2,3
1College of Animal Science and Technology, China Agricultural UniversityBeijing 100094, People's Republic of China
2Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences751 24 Uppsala, Sweden
3Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala Biomedical CentrePO Box 597, 751 24 Uppsala, Sweden

Tóm tắt

Mitochondrial DNA (mtDNA) diversity in European and Asian pigs was assessed using 1536 samples representing 45 European and 21 Chinese breeds. Diagnostic nucleotide differences in the cytochromeb(Cytb) gene between the European and Asian mtDNA variants were determined by pyrosequencing as a rapid screening method. Subsequently, 637 bp of the hypervariable control region was sequenced to further characterize mtDNA diversity. All sequences belonged to the D1 and D2 clusters of pig mtDNA originating from ancestral wild boar populations in Europe and Asia, respectively. The average frequency of Asian mtDNA haplotypes was 29% across European breeds, but varied from 0 to 100% within individual breeds. A neighbour-joining (NJ) tree of control region sequences showed that European and Asian haplotypes form distinct clusters consistent with the independent domestication of pigs in Asia and Europe. The Asian haplotypes found in the European pigs were identical or closely related to those found in domestic pigs from Southeast China. The star-like pattern detected by network analysis for both the European and Asian haplotypes was consistent with a previous demographic expansion. Mismatch analysis supported this notion and suggested that the expansion was initiated before domestication.

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Tài liệu tham khảo

Avise J.C Molecular markers natural history and evolution. 1st edn. 1994 London:Chapman & Hall.

10.1093/oxfordjournals.molbev.a026036

10.1073/pnas.76.4.1967

10.1038/nrg1203

10.1186/1297-9686-36-1-97

Clutton-Brock J, 1987, A natural history of domesticated mammals, 71

Darwin C The variation of animals and plants under domestication. 1868 London:John Murry.

Epstein J, 1984, Evolution of domesticated animals, 145

Excoffier L, 1992, Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data, Genetics, 131, 479, 10.1093/genetics/131.2.479

10.1046/j.1365-2052.2002.00898.x

10.1111/j.1365-2052.2004.01234.x

Fang M. Berg F. Ducos A. & Andersson L. Submitted. Mitochondrial haplotypes of European wild boar with 2 n =36 are closely related to those of European domestic pigs with 2 n =38.

Giuffra E, 2000, The origin of the domestic pig: independent domestication and subsequent introgression, Genetics, 154, 1785, 10.1093/genetics/154.4.1785

Harpending H.C, 1994, Signature of ancient population growth in a low resolution mitochondrial DNA mismatch distribution, Hum. Biol, 66, 591

10.1016/j.tig.2005.11.006

Jones G.F, 1998, The genetics of the pig, 17

10.1007/s002390010158

10.1046/j.1365-2052.2002.00784.x

10.1126/science.1096342

10.1093/bioinformatics/17.12.1244

10.1126/science.1106927

Nei M Molecular evolutionary genetics. 1987 New York:Columbia University Press.

10.1046/j.1365-2052.2001.00757.x

10.1007/PL00006487

Rogers A.R, 1992, Population growth makes waves in the distribution of pairwise genetic differences, Mol. Biol. Evol, 9, 552

Schneider S Roessli D& Excoffier L Arlequin version 2.0. A software for population genetic data analysis. 2000 Switzerland:Genetics and Biometry Laboratory University of Geneva Geneva.

10.1111/j.1365-2052.1997.00108.x

Tajima F, 1989, Statistical method for testing the neutral mutation hypothesis by DNA polymorphism, Genetics, 123, 585, 10.1093/genetics/123.3.585

10.1007/PL00006388

10.1007/s002390010156

10.1016/S0074-7696(08)62066-5

10.1186/1297-9686-35-7-657

Zhang Z.G. 1986 Shanghai:Shanghai Scientific & Technical Publishers.

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Proceedings of the Royal Society B: Biological Sciences

Tập 273 Số 1595

1803-1810

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