Misoprostol coadministered with diclofenac for prevention of gastroduodenal ulcers

Agrawal Nm1,2,3, Van Kerckhove He1,3,2, Erhardt Lj3,2,1, Geis Gs1,3,2
1Clinical Research Department, Searle Research & Development, Skokie
2Virga Jesse Ziekenhuis, Hasselt, Belgium
3From the Department of Gastroenterology, Ochsner Clinic, New Orleans

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Tài liệu tham khảo

Baum C, Kennedy DL, Forbes MB: Utilization of nonsteroidal anti-inflammatory drugs. Arthritis Rheum 28(6):686–692, 1985

IMS (Intercontinental Medical Statistics) Publications: Pharmaceutical Database Division: 1990. IMS America Ltd., Plymouth Meeting, Pennsylvania; and IMS Medical World Review: UK and IMS America, 1989

Larkai EN, Smith JL, Lidsky MD, Graham DY: Gastroduodenal mucosa and dyspeptic symptoms in arthritic patients during chronic nonsteroidal anti-inflammatory drug use. Am J Gastroenterol 82:1153–1158, 1987

Roth SH, Bennett RE: Nonsteroidal anti-inflammatory drug gastropathy. Arch Intern Med 147:2093–2100, 1987

Todd PA, Sorkin EM: Diclofenac sodium: A reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs 35:244–285, 1988

Geigy Pharmaceuticals: Voltaren (diclofenac sodium) prescribing information. September 1991

Griffin MR, Ray WA, Schaffner W: Nonsteroidal antiinflammatory drug use and death from peptic ulcer in elderly persons. Ann Intern Med 109:359–363, 1988

Geis GS, Stead H, Wallemark C-B, Nicholson PA: Prevalence of mucosal lesions in the stomach and duodenum due to chronic use of NSAID in patients with rheumatoid arthritis or osteoarthritis, and interim report on prevention by misoprostol of diclofenac associated lesions. J Rheumatol 18(suppl 28):11–14, 1991

Steiner JA: Misoprostol clinical pharmacology: Establishment of activity in man. Dig Dis Sci 30:136S-141S, 1985

Dajani EZ, Nissen CH: Gastrointestinal cytoprotective effects of misoprostol: Clinical efficacy overview. Dig Dis Sci 30:194S-200S, 1985

Wilson DE: Antisecretory and mucosal protective actions of misoprostol. Am J Med 83(suppl 1A):2–8, 1987

Agrawal NM, Godiwala T, Arimura A, Dajani EZ: Cytoprotection by a synthetic prostaglandin against ethanol-induced gastric mucosal damage: A double-blind endoscopic study in human subjects. Gastrointest Endosc 32(2):67–70, 1986

Lanza F, Peace K, Gustitus L, Rack MF, Dickson B: A blinded endoscopic comparative study of misoprostol versus sucralfate and placebo in the prevention of aspirin-induced gastric and duodenal ulceration. Am J Gastroenterol 83:143–146, 1988

Lanza FL: A double-blind study of prophylactic effect of misoprostol on lesions of the gastric and duodenal mucosa induced by oral administration of tolmetin in healthy subjects. Dig Dis Sci 31:131S-136S, 1986

Aadland E, Fausa O, Vatn M, Cohen H, Quinlan D: Protection by misoprostol against naproxen-induced gastric mucosal damage. Am J Med 83(suppl 1A):37–40, 1987

Roth S, Agrawal N, Mahowald M, Montoya H, Robbins D, Miller S, Nutting E, Woods E, Crager M, Nissen C, Swabb E: Misoprostol heals gastroduodenal injury in patients with rheumatoid arthritis receiving aspirin. Arch Intern Med 149:775–779, 1989

Graham DY, Agrawal NM, Roth SH: Prevention of NSAID-induced gastric ulcer with misoprostol: Multicentre, double-blind, placebo-controlled trial. Lancet 3:1277–1280, 1988

Agrawal NM, Roth S, Graham DY, White RH, Germain B, Brown JA, Stromatt SC: Misoprostol compared with sucralfate in the prevention of nonsteroidal anti-inflammatory drug-induced gastric ulcer. Ann Intern Med 115:195–200, 1991

Kaplan EL, Meier P: Nonparametric estimation from incomplete observation. J Am Stat Soc 53:457–481, 1958

Peto R, Peto J: Asymptotically efficient rank invariant procedures. J R Stat Soc 135 (series A):185–207, 1972

Fleiss JL: Statistical Methods for Rates and Proportions, 2nd ed. New York, John Wiley & Sons, 1981

Skoutakis VA, Carter CA, Mickle TR, Smith VH, Arkin CR, Alissandratos J, Petty DE: Review of diclofenac and evaluation of its place in therapy as a nonsteroidal antiinflammatory agent. Drug Intell Clin Pharm 22:850–859, 1988

Willkens RF: Worldwide clinical safety experience with diclofenac. Semin Arthritis Rheum 15(suppl 1):105–110, 1985

Catalano MA: Worldwide safety experience with diclofenac. Am J Med 80(suppl 4B):81–87, 1986

O'Brien WM: Adverse reactions to nonsteroidal antiinflammatory drugs. Am J Med 90(suppl 4B):70–80, 1986