Microfluidics and its applications in quantitative biology

Whitesides, G. M. (2006) The origins and the future of microfluidics. Nature, 442, 368–373 Lambert, G., Liao, D. and Austin, R. H. (2010) Collective escape of chemotactic swimmers through microscopic ratchets. Phys. Rev. Lett., 104, 168102 Loutherback, K., Chou, K. S., Newman, J., Puchalla, J., Austin, R. H., Sturm, J. C. (2010) Improved performance of deterministic lateral displacement arrays with triangular posts. Microfluidics and Nanofluidics, 9, 1143–1149 Zhang, Q. and Austin, R. H. (2012) Applications of microfluidics in stem cell biology. Bionanoscience, 2, 277–286 Zhu, X., Si, G., Deng, N., Ouyang, Q., Wu, T., He, Z., Jiang, L., Luo, C. and Tu, Y. (2012) Frequency-dependent Escherichia coli chemotaxis behavior. Phys. Rev. Lett., 108, 128101 Tian, Y., Luo, C., Lu, Y., Tang, C. and Ouyang, Q. (2012) Cell cycle synchronization by nutrient modulation. Integr. Biol. (Camb.), 4, 328–334 Floris, A., Staal, S., Lenk, S., Staijen, E., Kohlheyer, D., Eijkel, J. and van den Berg, A. (2010) A prefilled, ready-to-use electrophoresis based lab-on-a-chip device for monitoring lithium in blood. Lab Chip, 10, 1799–1806 van der Meer, A. D. and van den Berg, A. (2012) Organs-on-chips: breaking the in vitro impasse. Integr. Biol. (Camb.), 4, 461–470 Yuan, B., Jin, Y., Sun, Y., Wang, D., Sun, J. S., Wang, Z., Zhang, W., Jiang, X. Y. (2012) Artificial vessels: A strategy for depositing different types of cells in three dimensions to mimic tubular structures in tissues. Adv. Mater., 24, 853 Gong, P. Y., Zheng, W. F., Huang, Z., Zhang, W., Xiao, D., Jiang, X. Y. (2013) A strategy for the construction of controlled, three dimensional, multilayered, tissue-like structures. Adv. Funct. Mater., 23, 42–46 Luo, C. X., Liu, L., Ni, X. F., Wang, L., Nomura, S. M., Ouyang, Q., Chen, Y. (2011) Differentiating stem cells on patterned substrates for neural network formation. Microelectron. Eng., 88, 1707–1710 Li, J. J., Zhou, X. T., Shi, J., Zhang, F., Li, X., Jiang, L. M., Chen, Y. (2013) Upside and downside views of adherent cells on patterned substrates: Three-dimensional image reconstruction. Microelectron. Eng., 110, 365–368 Zhang, Q., Liu, T. and Qin, J. (2012) A microfluidic-based device for study of transendothelial invasion of tumor aggregates in realtime. Lab Chip, 12, 2837–2842 Ma, J., Hui, Y. S., Zhang, M., Yu, Y., Wen, W. and Qin, J. (2013) Facile synthesis of biomimetic honeycomb material with biological functionality. Small, 9, 497–503 Kalinin, Y. V., Jiang, L., Tu, Y. and Wu, M. (2009) Logarithmic sensing in Escherichia coli bacterial chemotaxis. Biophys. J., 96, 2439–2448 Kim, B. J., Hannanta-anan, P., Chau, M., Kim, Y. S., Swartz, M. A. and Wu, M. (2013) Cooperative roles of SDF-1α and EGF gradients on tumor cell migration revealed by a robust 3D microfluidic model. PLoS ONE, 8, e68422 Kim, B. J. and Wu, M. (2012) Microfluidics for mammalian cell chemotaxis. Ann Biomed Eng, 40, 1316–1327 Breslauer, D. N., Lee, P. J. and Lee, L. P. (2006) Microfluidics-based systems biology. Mol Biosyst, 2, 97–112 Gutierrez, M. P. and Lee, L. P. (2013) Multiscale design and integration of sustainable building functions. Science, 341, 247–248 Zhang, Y., Luo, C., Zou, K., Xie, Z., Brandman, O., Ouyang, Q. and Li, H. (2012) Single cell analysis of yeast replicative aging using a new generation of microfluidic device. PLoS ONE, 7, e48275 Xie, Z., Zhang, Y., Zou, K., Brandman, O., Luo, C., Ouyang, Q. and Li, H. (2012) Molecular phenotyping of aging in single yeast cells using a novel microfluidic device. Aging Cell, 11, 599–606 Bi, S., Yu, D., Si, G., Luo, C., Li, T., Ouyang, Q., Jakovljevic, V., Sourjik, V., Tu, Y. and Lai, L. (2013) Discovery of novel chemoeffectors and rational design of Escherichia coli chemoreceptor specificity. Proc. Natl. Acad. Sci. U.S.A., 110, 16814–16819 Mohammadi, A., Byrne Rodgers, J., Kotera, I. and Ryu, W. S. (2013) Behavioral response of Caenorhabditis elegans to localized thermal stimuli. BMC Neurosci, 14, 66 Ghosh, R., Mohammadi, A., Kruglyak, L. and Ryu, W. S. (2012) Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans. BMC Biol., 10, 85 Nandagopal, S., Wu, D. and Lin, F. (2011) Combinatorial guidance by CCR7 ligands for T lymphocytes migration in co-existing chemokine fields. PLoS ONE, 6, e18183 Jiang, L., Ouyang, Q. and Tu, Y. (2010) Quantitative modeling of Escherichia coli chemotactic motion in environments varying in space and time. PLoS Comput. Biol., 6, e1000735 Si, G., Wu, T., Ouyang, Q. and Tu, Y. (2012) Pathway-based mean-field model for Escherichia coli chemotaxis. Phys. Rev. Lett., 109, 048101 Rotem, A., Abate, A. R., Utada, A. S., Van Steijn, V. and Weitz, D. A. (2012) Drop formation in non-planar microfluidic devices. Lab Chip, 12, 4263–4268 Mazutis, L., Gilbert, J., Ung, W. L., Weitz, D. A., Griffiths, A. D. and Heyman, J. A. (2013) Single-cell analysis and sorting using dropletbased microfluidics. Nat. Protoc., 8, 870–891 Du, W., Li, L., Nichols, K. P. and Ismagilov, R. F. (2009) SlipChip. Lab Chip, 9, 2286–2292 Wei, P., Wong, W. W., Park, J. S., Corcoran, E. E., Peisajovich, S. G., Onuffer, J. J., Weiss, A. and Lim, W. A. (2012) Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature, 488, 384–388