Microfluidic Multiplexing in Bioanalyses

SLAS Technology - Tập 18 - Trang 350-366 - 2013
M. Kursad Araz1, Augusto M. Tentori2, Amy E. Herr1,2
1Department of Bioengineering, University of California, Berkeley, CA, USA
2The UC Berkeley/UCSF Graduate Program in Bioengineering, Berkeley, CA, USA

Tài liệu tham khảo

Yalow, 1959, Assay of Plasma Insulin in Human Subjects by Immunological Methods, Nature, 184, 1648, 10.1038/1841648b0 Ekins, 1960, The Estimation of Thyroxine in Human Plasma by an Electrophoretic Technique, Clin. Chim. Acta, 5, 453, 10.1016/0009-8981(60)90051-6 Berry, 2011, One-Step Purification of Nucleic Acid for Gene Expression Analysis via Immiscible Filtration Assisted by Surface Tension (IFAST), Lab Chip, 11, 1747, 10.1039/c1lc00004g McKenna, 2011, A Parallel Microfluidic Flow Cytometer for High-Content Screening, Nat. Meth., 8, 401, 10.1038/nmeth.1595 Kozak, 2013, Micro-Volume Wall-Less Immunoassays Using Patterned Planar Plates, Lab Chip, 13, 1342, 10.1039/c3lc40973b Ng, 2012, Digital Microfluidic Magnetic Separation for Particle-Based Immunoassays, Anal. Chem., 84, 8805, 10.1021/ac3020627 Bogojevic, 2012, A Digital Microfluidic Method for Multiplexed Cell-Based Apoptosis Assays, Lab Chip, 12, 627, 10.1039/C2LC20893H Kreutz, 2011, Theoretical Design and Analysis of Multivolume Digital Assays with Wide Dynamic Range Validated Experimentally with Microfluidic Digital PCR, Anal. Chem., 83, 8158, 10.1021/ac201658s Garcia-Cordero, 2013, Multiplexed Surface Micropatterning of Proteins with a Pressure-Modulated Microfluidic Button-Membrane, Chem. Commun., 49, 1264, 10.1039/C2CC37740C Hughes, 2012, Microfluidic Integration for Automated Targeted Proteomic Assays, Proc. Natl. Acad. Sci. U. S. A., 109, 5972, 10.1073/pnas.1108617109 White, 2011, Wash-free, Electrochemical Platform for the Quantitative, Multiplexed Detection of Specific Antibodies, Anal. Chem., 84, 1098, 10.1021/ac202757c Wu, 2012, High Throughput Automated Chromatin Immunoprecipitation as a Platform for Drug Screening and Antibody Validation, Lab Chip, 12, 2190, 10.1039/c2lc21290k Park, 2012, Lab-on-a-Disc for Fully Integrated Multiplex Immunoassays, Anal. Chem., 84, 2133, 10.1021/ac203163u Apori, 2013, Microfluidic Validation of Diagnostic Protein Markers for Spontaneous Cerebrospinal Fluid Rhinorrhea, J. Proteome Res., 12, 1254, 10.1021/pr300928p Jung, 2011, An Integrated Passive Micromixer-Magnetic Separation-Capillary Electrophoresis Microdevice for Rapid and Multiplex Pathogen Detection at the Single-Cell Level, Lab Chip, 11, 3465, 10.1039/c1lc20350a Shen, 2011, Multiplexed Quantification of Nucleic Acids with Large Dynamic Range Using Multivolume Digital RT-PCR on a Rotational SlipChip Tested with HIV and Hepatitis C Viral Load, J. Am. Chem. Soc., 133, 17705, 10.1021/ja2060116 Dahler-Eriksen, 1997, C-Reactive Protein in General Practice: How Commonly Is It Used and Why?, Scand. J. Prim. Health Care, 15, 35, 10.3109/02813439709043427 Watson, 2012, Raised Inflammatory Markers, BMJ, 344, e454, 10.1136/bmj.e454 Ehl, 1997, C-Reactive Protein Is a Useful Marker for Guiding Duration of Antibiotic Therapy in Suspected Neonatal Bacterial Infection, Pediatrics, 99, 216, 10.1542/peds.99.2.216 Fearon, 2005, The Laboratory Diagnosis of HIV Infections, Can. J. Infect. Dis. Med. Microbiol., 16, 26, 10.1155/2005/515063 1998 2011 Huang, 2013, An Integrated Microfluidic Cell Culture System for High-Throughput Perfusion Three-Dimensional Cell Culture-Based Assays: Effect of Cell Culture Model on the Results of Chemosensitivity Assays, Lab Chip, 13, 1133, 10.1039/c2lc41264k Das, 2013, Empirical Chemosensitivity Testing in a Spheroid Model of Ovarian Cancer Using a Microfluidics-Based Multiplex Platform, Biomicrofluidics, 7, 011805, 10.1063/1.4774309 Choi, 2013, Rapid Antibiotic Susceptibility Testing by Tracking Single Cell Growth in a Microfluidic Agarose Channel System, Lab Chip, 13, 280, 10.1039/C2LC41055A Kim, 2012, A Programmable Microfluidic Cell Array for Combinatorial Drug Screening, Lab Chip, 12, 1813, 10.1039/c2lc21202a Mao, 2012, Imitation of Drug Metabolism in Human Liver and Cytotoxicity Assay Using a Microfluidic Device Coupled to Mass Spectrometric Detection, Lab Chip, 12, 219, 10.1039/C1LC20678H Brouzes, 2009, Droplet Microfluidic Technology for Single-Cell High-Throughput Screening, Proc. Natl. Acad. Sci. U. S. A., 106, 14195, 10.1073/pnas.0903542106 Heller, 2013, Genome-wide CpG Island Methylation Analyses in Non–Small Cell Lung Cancer Patients, Carcinogenesis, 34, 513, 10.1093/carcin/bgs363 Wu, 2013, Single Cell MicroRNA Analysis Using Microfluidic Flow Cytometry, PLoS One, 8, e55044, 10.1371/journal.pone.0055044 Xiang, 2011, A Reagentless, Disposable and Multiplexed Electronic Biosensing Platform: Application to Molecular Logic Gates, Biosens. Bioelectron., 26, 3077, 10.1016/j.bios.2010.12.010 White, 2011, High-Throughput Microfluidic Single-Cell RT-qPCR, Proc. Natl. Acad. Sci. U. S. A., 108, 13999, 10.1073/pnas.1019446108 Wu, 2012, Microfluidically-Unified Cell Culture, Sample Preparation, Imaging and Flow Cytometry for Measurement of Cell Signaling Pathways with Single Cell Resolution, Lab Chip, 12, 2823, 10.1039/c2lc40344g Lynn, 2011, Mapping Spatiotemporal Molecular Distributions Using a Microfluidic Array, Anal. Chem., 84, 1360, 10.1021/ac202314n Mao, 2012, Multinozzle Emitter Array Chips for Small-Volume Proteomics, Anal. Chem., 85, 816, 10.1021/ac3032965 Feinberg, 1961, A ‘Microspot’ Test for Antigens and Antibodies, Nature, 192, 985, 10.1038/192985a0 Ekins, 1990, Fluorescence Spectroscopy and Its Application to a New Generation of High Sensitivity, Multi-Microspot, Multianalyte, Immunoassay, Clin. Chim. Acta, 194, 91, 10.1016/0009-8981(90)90305-C Ekins, 1990, Multispot, Multianalyte, Immunoassay, Ann. Biol. Clin. (Paris), 48, 655 Kim, 2009, Microfluidic Sample Preparation: Cell Lysis and Nucleic Acid Purification, Integr. Biol., 1, 574, 10.1039/b905844c Wu, 2010, Modular Integration of Electronics and Microfluidic Systems Using Flexible Printed Circuit Boards, Lab Chip, 10, 519, 10.1039/B922830F Jain, 2007, Applications of Nanobiotechnology in Clinical Diagnostics, Clin. Chem., 53, 2002, 10.1373/clinchem.2007.090795 Choi, 2012, Digital Microfluidics, Annu. Rev. Anal. Chem., 5, 413, 10.1146/annurev-anchem-062011-143028 Gordon, 2013, Discerning Trends in Multiplex Immunoassay Technology with Potential for Resource-Limited Settings, Lab Med Online, 3, 62, 10.3343/lmo.2013.3.1.62 Chang, 2013, Nucleic Acid Amplification Using Microfluidic Systems, Lab Chip, 13, 1225, 10.1039/c3lc41097h Kovarik, 2013, Micro Total Analysis Systems: Fundamental Advances and Applications in the Laboratory, Clinic, and Field, Anal. Chem., 85, 451, 10.1021/ac3031543 Mairhofer, 2009, Microfluidic Systems for Pathogen Sensing: A Review, Sensors (Basel), 9, 4804, 10.3390/s90604804 Kovarik, 2012, Micro Total Analysis Systems for Cell Biology and Biochemical Assays, Anal. Chem., 84, 516, 10.1021/ac202611x Bernard, 2000, Micromosaic Immunoassays, Anal. Chem., 73, 8, 10.1021/ac0008845 Bailey, 2007, DNA-Encoded Antibody Libraries: A Unified Platform for Multiplexed Cell Sorting and Detection of Genes and Proteins, J. Am. Chem. Soc., 129, 1959, 10.1021/ja065930i Fan, 2008, Integrated Barcode Chips for Rapid, Multiplexed Analysis of Proteins in Microliter Quantities of Blood, Nat. Biotechnol., 26, 1373, 10.1038/nbt.1507 Chin, 2011, Microfluidics-Based Diagnostics of Infectious Diseases in the Developing World, Nat. Med., 17, 1015, 10.1038/nm.2408 Zetola, 2007, Syphilis and HIV Infection: An Update, Clin. Infect. Dis., 44, 1222, 10.1086/513427 Henares, 2007, Multiple Enzyme Linked Immunosorbent Assay System on a Capillary-Assembled Microchip Integrating Valving and Immuno-reaction Functions, Anal. Chim. Acta, 589, 173, 10.1016/j.aca.2007.02.060 Didar, 2011, Patterning Multiplex Protein Microarrays in a Single Microfluidic Channel, Anal. Chem., 84, 1012, 10.1021/ac2025877 Maerkl, 2007, A Systems Approach to Measuring the Binding Energy Landscapes of Transcription Factors, Science, 315, 233, 10.1126/science.1131007 Zheng, 2012, High-Throughput Immunoassay through In-Channel Microfluidic Patterning, Lab Chip, 12, 2487, 10.1039/c2lc40145b Garcia-Cordero, 2013, A High-Throughput Nanoimmunoassay Chip Applied to Large-Scale Vaccine Adjuvant Screening, Integr. Biol. (Camb.), 5, 650, 10.1039/c3ib20263a Squires, 2008, Making It Stick: Convection, Reaction and Diffusion in Surface-Based Biosensors, Nat. Biotechnol., 26, 417, 10.1038/nbt1388 Araz, M. K., Chung-Hoon, L., Lal, A. In Ultrasonic Separation in Microfluidic Capillaries, 2003 IEEE Symposium on Ultrasonics, Honolulu, HI, October 5–8, 2003. Wiklund, 2006, Ultrasonic Enhancement of Bead-Based Bioaffinity Assays, Lab Chip, 6, 1279, 10.1039/b609184a Liberale, 2013, Integrated Microfluidic Device for Single-Cell Trapping and Spectroscopy, Sci. Rep., 3, 1258, 10.1038/srep01258 Hua, 2010, Multiplexed Real-Time Polymerase Chain Reaction on a Digital Microfluidic Platform, Anal. Chem., 82, 2310, 10.1021/ac902510u Auerswald, 2005, Fast Immobilization of Probe Beads by Dielectrophoresis-Controlled Adhesion in a Versatile Microfluidic Platform for Affinity Assay, Electrophoresis, 26, 3697, 10.1002/elps.200500401 Surviladze, 2012, High-Throughput Flow Cytometry Bead-Based Multiplex Assay for Identification of Rho GTPase Inhibitors, 253 Walton, 2002, Particles for Multiplexed Analysis in Solution: Detection and Identification of Striped Metallic Particles Using Optical Microscopy, Anal. Chem., 74, 2240, 10.1021/ac020073w Lee, 2010, Colour-Barcoded Magnetic Microparticles for Multiplexed Bioassays, Nat. Mater., 9, 745, 10.1038/nmat2815 Kim, 2009, Structural Colour Printing Using a Magnetically Tunable and Lithographically Fixable Photonic Crystal, Nat. Photon, 3, 534, 10.1038/nphoton.2009.141 Klostranec, 2007, Convergence of Quantum Dot Barcodes with Microfluidics and Signal Processing for Multiplexed High-Throughput Infectious Disease Diagnostics, Nano Lett., 7, 2812, 10.1021/nl071415m Gao, 2013, Automating Quantum Dot Barcode Assays Using Microfluidics and Magnetism for the Development of a Point-of-Care Device, ACS Appl. Mater. Interfaces, 5, 2853, 10.1021/am302633h Giri, 2011, Rapid Screening of Genetic Biomarkers of Infectious Agents Using Quantum Dot Barcodes, ACS Nano, 5, 1580, 10.1021/nn102873w Vignali, 2000, Multiplexed Particle-Based Flow Cytometric Assays, J. Immunol. Methods, 243, 243, 10.1016/S0022-1759(00)00238-6 Yu, 2012, Multiplex Competitive Microbead-Based Flow Cytometric Immunoassay Using Quantum Dot Fluorescent Labels, Anal. Chim. Acta, 750, 191, 10.1016/j.aca.2012.05.017 Elshal, 2006, Multiplex Bead Array Assays: Performance Evaluation and Comparison of Sensitivity to ELISA, Methods, 38, 317, 10.1016/j.ymeth.2005.11.010 Zeng, 2010, High-Performance Single Cell Genetic Analysis Using Microfluidic Emulsion Generator Arrays, Anal. Chem., 82, 3183, 10.1021/ac902683t Sista, 2008, Heterogeneous Immunoassays Using Magnetic Beads on a Digital Microfluidic Platform, Lab Chip, 8, 2188, 10.1039/b807855f Froumkine, 1936 Sista, 2011, Digital Microfluidic Platform for Multiplexing Enzyme Assays: Implications for Lysosomal Storage Disease Screening in Newborns, Clin. Chem., 57, 1444, 10.1373/clinchem.2011.163139 Moon, 2006, An Integrated Digital Microfluidic Chip for Multiplexed Proteomic Sample Preparation and Analysis by MALDI-MS, Lab Chip, 6, 1213, 10.1039/b601954d Noroozi, 2011, A Multiplexed Immunoassay System Based upon Reciprocating Centrifugal Microfluidics, Rev. Sci. Instrum., 82, 064303, 10.1063/1.3597578 Hou, 2010, Ultrashort Separation Length Homogeneous Electrophoretic Immunoassays Using On-Chip Discontinuous Polyacrylamide Gels, Anal. Chem., 82, 3343, 10.1021/ac100182j Tia, 2011, Multianalyte On-Chip Native Western Blotting, Anal. Chem., 83, 3581, 10.1021/ac200322z Hughes, 2012, Microfluidic Western Blotting, Proc. Natl. Acad. Sci. U. S. A., 109, 21450, 10.1073/pnas.1207754110 Bromberg, 2012, Microfabricated Linear Hydrogel Microarray for Single-Nucleotide Polymorphism Detection, Anal. Chem., 84, 963, 10.1021/ac202303f Ngom, 2010, Development and Application of Lateral Flow Test Strip Technology for Detection of Infectious Agents and Chemical Contaminants: A Review, Anal. Bioanal. Chem., 397, 1113, 10.1007/s00216-010-3661-4 Towbin, 1979, Electrophoretic Transfer of Proteins from Polyacrylamide Gels to Nitrocellulose Sheets: Procedure and Some Applications, Proc. Natl. Acad. Sci. U. S. A., 76, 4350, 10.1073/pnas.76.9.4350 Martinez, 2008, Three-Dimensional Microfluidic Devices Fabricated in Layered Paper and Tape, Proc. Natl. Acad. Sci. U. S. A., 105, 19606, 10.1073/pnas.0810903105 Cheng, 2010, Paper-Based ELISA, Angew. Chem. Int. Ed., 49, 4771, 10.1002/anie.201001005 Carrilho, 2009, Paper Microzone Plates, Anal. Chem., 81, 5990, 10.1021/ac900847g Lafleur, 2012, Progress toward Multiplexed Sample-to-Result Detection in Low Resource Settings Using Microfluidic Immunoassay Cards, Lab Chip, 12, 1119, 10.1039/c2lc20751f Kifude, 2008, Enzyme-Linked Immunosorbent Assay for Detection of Plasmodium falciparum Histidine-Rich Protein 2 in Blood, Plasma, and Serum, Clin. Vaccine Immunol., 15, 1012, 10.1128/CVI.00385-07 Mao, 2012, Microfluidic Diagnostics for the Developing World, Lab Chip, 12, 1412, 10.1039/c2lc90022j Martinez, 2010, Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices, Anal. Chem., 82, 3, 10.1021/ac9013989 Thorsen, 2002, Microfluidic Large-Scale Integration, Science, 298, 580, 10.1126/science.1076996 Melin, 2007, Microfluidic Large-Scale Integration: The Evolution of Design Rules for Biological Automation, Annu. Rev. Biophys. Biomol. Struct., 36, 213, 10.1146/annurev.biophys.36.040306.132646 Hansen, 2004 Hong, 2004, A Nanoliter-Scale Nucleic Acid Processor with Parallel Architecture, Nat. Biotechnol., 22, 435, 10.1038/nbt951 Ottesen, 2006, Microfluidic Digital PCR Enables Multigene Analysis of Individual Environmental Bacteria, Science, 314, 1464, 10.1126/science.1131370 Kalisky, 2011, Single-Cell Genomics, Nat. Methods, 8, 311, 10.1038/nmeth0411-311 Fan, 2011, Whole-Genome Molecular Haplotyping of Single Cells, Nat. Biotechnol., 29, 51, 10.1038/nbt.1739 Skelley, 2005, Development and Evaluation of a Microdevice for Amino Acid Biomarker Detection and Analysis on Mars, Proc. Natl. Acad. Sci. U. S. A., 102, 1041, 10.1073/pnas.0406798102 White, 2012, Digital PCR Provides Absolute Quantitation of Viral Load for an Occult RNA Virus, J. Virol. Methods, 179, 45, 10.1016/j.jviromet.2011.09.017 Liu, 2003, Solving the “World-to-Chip” Interface Problem with a Microfluidic Matrix, Anal. Chem., 75, 4718, 10.1021/ac0346407 Du, 2009, SlipChip, Lab Chip, 9, 2286, 10.1039/b908978k Shen, 2010, Nanoliter Multiplex PCR Arrays on a SlipChip, Anal. Chem., 82, 4606, 10.1021/ac1007249 Song, 2012, Multiplexed Volumetric Bar-Chart Chip for Point-of-Care Diagnostics, Nat. Commun., 3, 1283, 10.1038/ncomms2292 Thorsen, 2001, Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device, Phys. Rev. Lett., 86, 4163, 10.1103/PhysRevLett.86.4163 Gañán-Calvo, 2001, Perfectly Monodisperse Microbubbling by Capillary Flow Focusing, Phys. Rev. Lett., 87, 274501, 10.1103/PhysRevLett.87.274501 Song, 2006, Reactions in Droplets in Microfluidic Channels, Angew. Chem. Int. Ed. Engl., 45, 7336, 10.1002/anie.200601554 Guo, 2012, Droplet Microfluidics for High-Throughput Biological Assays, Lab Chip, 12, 2146, 10.1039/c2lc21147e Seemann, 2012, Droplet Based Microfluidics, Rep. Prog. Phys., 75, 016601, 10.1088/0034-4885/75/1/016601 Meyer, 2007, Targeted High-Throughput Sequencing of Tagged Nucleic Acid Samples, Nucleic Acids Res., 35, e97, 10.1093/nar/gkm566 Han, 2001, Quantum-Dot-Tagged Microbeads for Multiplexed Optical Coding of Biomolecules, Nat. Biotechnol., 19, 631, 10.1038/90228 Chen, 2012, Multiplexed Protease Activity Assay for Low-Volume Clinical Samples Using Droplet-Based Microfluidics and Its Application to Endometriosis, J. Am. Chem. Soc., 135, 1645, 10.1021/ja307866z Sjostrom, 2013, Multiplex Analysis of Enzyme Kinetics and Inhibition by Droplet Microfluidics Using Picoinjectors, Lab Chip, 13, 1754, 10.1039/c3lc41398e Lee, 2012, A Sensitive and Reliable Detection of Thrombin via Enzyme-Precipitate-Coating-Linked Aptamer Assay, Chem. Commun., 48, 5971, 10.1039/c2cc30710c Stern, 2010, Label-Free Biomarker Detection from Whole Blood, Nat. Nanotechnol., 5, 138, 10.1038/nnano.2009.353 Bai, 2004, Design and Synthesis of a Photocleavable Biotinylated Nucleotide for DNA Analysis by Mass Spectrometry, Nucleic Acids Res., 32, 535, 10.1093/nar/gkh198 Peoples, 2010, Translational Research Needed in Microfluidics and Immunoaffinity Separations, Bioanalysis, 2, 1667, 10.4155/bio.10.132 Chin, 2012, Commercialization of Microfluidic Point-of-Care Diagnostic Devices, Lab Chip, 12, 2118, 10.1039/c2lc21204h Anderson, 2005, The Roles of Multiple Proteomic Platforms in a Pipeline for New Diagnostics, Mol. Cell. Proteomics, 4, 1441, 10.1074/mcp.I500001-MCP200 Zolg, 2006, The Proteomic Search for Diagnostic Biomarkers: Lost in Translation?, Mol. Cell. Proteomics, 5, 1720, 10.1074/mcp.R600001-MCP200 Rifai, 2006, Protein Biomarker Discovery and Validation: The Long and Uncertain Path to Clinical Utility, Nat. Biotech., 24, 971, 10.1038/nbt1235 Unger, 2000, Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography, Science, 288, 113, 10.1126/science.288.5463.113