Thay đổi hồ sơ MicroRNA ở những người dương tính với virus gây suy giảm miễn dịch ở người loại 1 (HIV-1)
Tóm tắt
MicroRNA (miRNA) đóng vai trò đa dạng trong việc điều tiết các chức năng tế bào và phát triển. Chúng tôi đã đánh giá sự biểu hiện của miRNA trong các tế bào bạch cầu đơn nhân từ 36 cá nhân dương tính với HIV-1 và 12 người kiểm soát bình thường. Các cá nhân dương tính với HIV-1 được phân loại theo quy trình thành bốn nhóm dựa trên số lượng tế bào T CD4+ và tải lượng virus của họ. Chúng tôi báo cáo rằng các dấu hiệu miRNA đặc trưng có thể được quan sát cho mỗi nhóm trong bốn nhóm này.
Từ khóa
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