Methods for Determining the Presence of Tranquilizers and Other New Drugs in Urine of Dogs
Tóm tắt
An attempt has been made to work out general methods of determining the presence of recent drugs, among others, tranquilizers. Colour reaction with cone. H2SO4, paper chromatography, and absorption in UV and certain special reactions have been tried. Ten of these substances have been given to dogs. After that attempts have been made to determine the presence of them in the urine from the dogs. Seven of these preparations were identified (for sure.
Tài liệu tham khảo
Algeri, E. J. a. J. T. Walker: Paper chromatography for identification of the common barbiturates. Amer. J. clin. Path. 1952, 22, 37.
Allgén, L.-G.: Separation and identification of barbiturates in biological material by paper chromatography. Spand. J. Clin. Lab. Inv. 1955, 7, Suppl. 20.
Amelink, F.: Rapid Microchemical Identification Methods in Pharmacy and Toxicology. Netherlands University Press, Amsterdam 1962.
Burger, E. a. H. Berninger: Zum papierchromatographischen und spektrophotometrischen Nachweis der Phenothiazinderivate unter toxikologischen Bedingungen. Arch. Tox. 1958, 17, 77.
Hoffman, A. J. a. B. J. Berninger: An improved colorimetric method for the determination of meprobamate in biological fluids. J. Amer. Pharm. Ass. Sci. 1959, 48, 740.
Hübner, G. u. E. Pfeil: Der Nachweis von Barbituraten. J. physiol. Chem. 1954, 296, 225.
Kinberger, B.: Snabbdiagnostik vid chlorpromazin- och prometazinförgiftningar. Sv. Läkartidning, 1956, 53, 2327.
Kinberger, B.: Om påvisande av antihistaminer och ataraxica. Sv. Läkartidning, 1958, 55, 27.
Moore, P. A.: The detection of “Doping”. Vet. Rec. 1957, 69, 1097.
Moraes, E. e. E. M. Palma: A chromatografia em papel aplieada à quimica toxicologica. An. da Fac. de Farm. e Odont. da Univ. de Sao Paulo, 1955, XII, 149.
Moraes, E. e. E. M. Palma: Pesquisa de barbitúricos em material biológico pela chromatografia em papel. An. da Fac. de Farm. e Odont. da Univ. de Sao Paulo, 1955, XII, 163.
Moraes, E. e. E. M. Palma: Pesquisa de depressores (“Doping” negativo) em amostras de sangue e urina dos calvados de corrida. An. Farm. Quim. Sao Paulo, 1958, 9, 5.
Moraes, E., D. Rieser, E. M. Palma e R. B. Sznelwar: Pesquisa de estimulantes (“Doping” positivo) em amostras de sangue e urine dos calvados de corrida. An. Farm. Quim. Sao Paulo, 1957, 8, 7.
Morgan, C. E.: Analysis of horse salive and urine for the detection of drugs. N. Y. State Racing Comm., State Racing Comm. Lab., Jamaica, New York, 1947.
Peterson, H.: Methods for the collection and analysis of horse saliva and urine for the detection of drugs. New York State Commission Laboratory, 1960.
Rehm, C. R., S. G. Slack a. W. J. Mader: Pharmaceuticals and related drugs. Anal. Chem. 1959, 31, 18.
Stewart, C. P. a. A. Stolman: Toxicology. Academic Press, New York a. London, 1960–61.
Wickström, A. a. B. Salvesen: The separation and identification of some barbiturates by paper partition chromatography. J. Pharm. Pharmac. 1952, IV, 98.
Zagel, S. A.: Application of paper chromatography to the control of doping. An. Fac. Quim. Y. Farm. Univ. Chile, 1960, 12, 18.