Phân tích kiểm soát chuyển hóa: Ứng dụng sinh học và hiểu biết

Gershenfeld N: The Nature of Mathematical Modeling. Cambridge University Press;. 1999 Bhalla US, Iyengar R: Emergent properties of networks of biological signaling pathways. Science. 1999, 283: 381-387. 10.1016/S0009-2614(97)01391-2. Collado-Vides J, Magasanik B, Smith TF: Integrative Approaches to Molecular Biology. Cambridge, MA: MIT Press;. 1996 Giersch C: Mathematical modeling of metabolism. Curr Opin Plant Biol. 2000, 3: 249-253. 10.1016/S1369-5266(00)00072-8. Palsson B: The challenges of in silico biology. Nat Biotechnol. 2000, 18: 1147-1150. 10.1038/81125. Fell DA, Wagner A: The small world of metabolism. Nat Biotechnol. 2000, 18: 1121-1122. 10.1038/81025. Weng G, Bhalla US, Iyengar R: Complexity in biological signaling systems. Science. 1999, 284: 92-96. 10.1016/S0925-8388(98)00740-3. Poolman MG, Fell DA, Thomas S: Modelling photosynthesis and its control. J Exp Bot. 2000, 51: 319-328. 10.1093/jexbot/51.suppl_1.319. Ni T-C, Savageau M: Application of biochemical systems theory to metabolism in human red blood cells. J Biol Chem. 1996, 271: 7927-7941. 10.1074/jbc.271.14.7927. Savageau MA: Power-law formalism: a canonical nonlinear approach to modeling and analysis. In World Congress of Nonlinear Analysts, 92, Vol 4. Edited by Lakshmikantham V. Berlin: Walter de Gruyter;. 1996 Schilling CH, Schuster S, Palsson BO, Heinrich R: Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era. Biotechnol Prog. 1999, 15: 296-303. 10.1021/bp990048k. Edwards JS, Palsson BO: Systems properties of the Haemophilus influenzae Rd metabolic genotype. J Biol Chem. 1999, 274: 17410-17416. 10.1074/jbc.274.25.17410. Jeong H., Tombor B, Albert R, Oltavai N, Barabasi A-L: The large-scale organization of metabolic networks. Nature. 2000, 407: 651-654. 10.1038/35036627. Fambrough D, McClure K, Kazlauskas A, Lander ES: Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes. Cell. 1999, 97: 727-741. Pawson T, Saxton TM: Signaling networks - do all roads lead to the same genes?. Cell. 1999, 97: 675-678. Kholodenko BN, Demin OV, Moehren G, Hoek JB: Quantification of short term signaling by the epidermal growth factor receptor. J Biol Chem. 1999, 274: 30169-30181. 10.1074/jbc.274.42.30169. Krauss S, Brand MD: Quantitation of signal transduction. FASEB J. 2000, 14: 2581-2588. 10.1096/fj.00-0064com. Kacser H, Burns JA: Control of enzyme flux. Symp Soc Exp Biol. 1973, 27: 65-104. Heinrich R, Rapoport TA: A linear steady-state treatment of enzymatic chains. Eur J Biochem. 1974, 42: 89-95. Fell DA: Metabolic control analysis - a survey of its theoretical and experimental development. Biochem J. 1992, 286: 313-330. Fell D: Understanding the Control of Metabolism. London: Portland Press;. 1997 Heinrich R, Schuster S: The Regulation of Cellular Systems. New York: Chapman and Hall;. 1996 Cornish-Bowden A: Metabolic control analysis in theory and practice. Adv Mol Cell Biol. 1995, 11: 21-64. MCA website. [http://gepasi.dbs.aber.ac.uk/metab/mca_home.htm] Bionet metabolic regulation newsgroup. [http://www.ibiblio.org/usenet-i/groups-html/bionet.metabolic-reg.html] Fell DA, Thomas S: Physiological control of metabolic flux: the requirement for multisite modulation. Biochem J. 1995, 311: 35-39. Niederberger P, Prasad R, Miozzari G, Kacser H: A strategy for increasing an in vivo flux by genetic manipulations of the tryptophan system of yeast. Biochem J. 1992, 287: 473-479. Schimke RT: Adaptive characteristics of urea cycle enzymes in the rat. J Biol Chem. 1962, 237: 459-468. Tavazoie S, Hughes JD, Campbell MJ, Cho RJ, Church GM: Systematic determination of genetic network architecture. Nat Genet. 1999, 22: 281-285. 10.1038/10343. Kacser H, Burns JA: The molecular basis of dominance. Genetics. 1981, 97: 639-666. Orr HA: A test of Fisher's theory of dominance. Proc Natl Acad Sci USA. 1991, 88: 11413-11415. Grossniklaus U, Madhusudhan MS, Nanjundiah V: Nonlinear enzyme kinetics can lead to high metabolic flux control coefficients: implications for the evolution of dominance. J Theor Biol. 1996, 182: 299-302. 10.1006/jtbi.1996.0167. The Arabidopsis Information Resource. [http://www.arabidopsis.org] Alliance for Cellular Signaling. [http://afcs.swmed.edu/] National Center for Atmospheric Research. [http://www.ncar.ucar.edu/ncar/index.html]