Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the -2578AA genotype

Journal of Medical Genetics - Tập 46 Số 12 - Trang 840-846 - 2009
Diether Lambrechts1,2, Koen Poesen1,2, Rubén Fernández‐Santiago3, Ammar Al‐Chalabi4, Dongsheng Fan5, Paul W.J. van Vught6, Seema A. Khan7, Stefan L. Marklund8, Alice Brockington9, Ingrid van Marion10, Johanna Anneser3, Christopher E. Shaw4, Albert C. Ludolph3, Nigel P. Leigh4, Giacomo P. Comi5, Thomas Gasser3, Pamela J. Shaw9, Karen Morrison10, P. M. Andersen8, Leonard H. van den Berg6, Vincent Thijs11, Teepu Siddique7, Peter Carmeliet12
1Department of Transgene Technology and Gene Therapy, VIB, Leuven, B-3000, Belgium
2The Center for Transgene Technology and Gene Therapy, K.U.Leuven, Leuven, B-3000, Belgium
3Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, Eberhard-Karls University, Tuebingen, Germany
4Departments of Neurology and Medical and Molecular Genetics, Guy's, King's and St Thomas' School of Medicine and Institute of Psychiatry, King's College London, London, UK
5Dino Ferrari Centre, Department of Neurological Sciences, University of Milan and IRCCS Foundation Ospedale Policlinico, Mangiagalli and Regina Elena, Milan, Italy
6Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
7The Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
8Department of Neurology, Umea University Hospital, and Institute of Clinical Neuroscience and Medical Genetics, Umea University, Sweden
9The Academic Neurology Unit, Medical School, University of Sheffield, Sheffield, UK
10Department of Clinical Neurosciences, Division of Neuroscience, The Medical School, University of Birmingham, Birmingham, UK
11Laboratory of Experimental Neurology, Campus Gasthuisberg, Leuven B-3000, Belgium
12Center for Transgene Technology and Gene Therapy, Flanders Interuniversity Institute for Biotechnology, KU Leuven, Campus Gasthuisberg, Herestraat 49, B-3000, Leuven, Belgium

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Journal of Medical Genetics

Tập 46 Số 12

840-846

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