Mendelian Randomization như một phương pháp đánh giá tính nguyên nhân sử dụng dữ liệu quan sát

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Pierce, 2013, Efficient design for Mendelian randomization studies: Subsample and 2-sample instrumental variable estimators., Am J Epidemiol, 178, 1177, 10.1093/aje/kwt084

Welsh, 2010, Unraveling the directional link between adiposity and inflammation: A bidirectional Mendelian randomization approach., J Clin Endocrinol Metab, 95, 93, 10.1210/jc.2009-1064

Palmer, 2013, Association of plasma uric acid with ischaemic heart disease and blood pressure: Mendelian randomisation analysis of two large cohorts., BMJ, 347, f4262, 10.1136/bmj.f4262

Burgess, 2015, Network Mendelian randomization: Using genetic variants as instrumental variables to investigate mediation in causal pathways., Int J Epidemiol, 44, 484, 10.1093/ije/dyu176

Relton, 2012, Two-step epigenetic Mendelian randomization: A strategy for establishing the causal role of epigenetic processes in pathways to disease., Int J Epidemiol, 41, 161, 10.1093/ije/dyr233

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Linsel-Nitschke, 2008, Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study., PLoS One, 3, e2986, 10.1371/journal.pone.0002986

Ference, 2012, Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: A Mendelian randomization analysis., J Am Coll Cardiol, 60, 2631, 10.1016/j.jacc.2012.09.017

Voight, 2012, Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study., Lancet, 380, 572, 10.1016/S0140-6736(12)60312-2

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Wensley, 2011, Association between C reactive protein and coronary heart disease: Mendelian randomisation analysis based on individual participant data., BMJ, 342, d548, 10.1136/bmj.d548

VanderWeele, 2014, Methodological challenges in mendelian randomization., Epidemiology, 25, 427, 10.1097/EDE.0000000000000081

Swerdlow, 2015, HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials., Lancet, 385, 351, 10.1016/S0140-6736(14)61183-1

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Hughes, 2014, Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function., Kidney Int, 85, 344, 10.1038/ki.2013.353

Yang, 2010, Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors., Circ Cardiovasc Genet, 3, 523, 10.1161/CIRCGENETICS.109.934455

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Benyamin, 2014, Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis., Nat Commun, 5, 4926, 10.1038/ncomms5926

Pattaro, 2012, Genome-wide association and functional follow-up reveals new loci for kidney function., PLoS Genet, 8, e1002584, 10.1371/journal.pgen.1002584

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Todd, 2015, Genetic evidence for a causal role of obesity in diabetic kidney disease., Diabetes, 64, 4238, 10.2337/db15-0254

Verduijn, 2011, Is fetuin-A a mortality risk factor in dialysis patients or a mere risk marker? A Mendelian randomization approach., Nephrol Dial Transplant, 26, 239, 10.1093/ndt/gfq402

Zoccali, 2006, Mendelian randomization: A new approach to studying epidemiology in ESRD., Am J Kidney Dis, 47, 332, 10.1053/j.ajkd.2005.10.027

Liu, 2004, Association between cholesterol level and mortality in dialysis patients: Role of inflammation and malnutrition., JAMA, 291, 451, 10.1001/jama.291.4.451

Boef, 2015, Mendelian randomization studies in the elderly., Epidemiology, 26, e15, 10.1097/EDE.0000000000000243

Böger, 2011, CUBN is a gene locus for albuminuria., J Am Soc Nephrol, 22, 555, 10.1681/ASN.2010060598

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Okada, 2012, Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations., Nat Genet, 44, 904, 10.1038/ng.2352

Gharavi, 2011, Genome-wide association study identifies susceptibility loci for IgA nephropathy., Nat Genet, 43, 321, 10.1038/ng.787

Yu, 2011, A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy., Nat Genet, 44, 178, 10.1038/ng.1047

Kiryluk, 2014, Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens., Nat Genet, 46, 1187, 10.1038/ng.3118

Köttgen, 2013, Genome-wide association analyses identify 18 new loci associated with serum urate concentrations., Nat Genet, 45, 145, 10.1038/ng.2500

Sandholm, 2013, Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes., J Am Soc Nephrol, 24, 1537, 10.1681/ASN.2012111122

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Brion, 2013, Calculating statistical power in Mendelian randomization studies., Int J Epidemiol, 42, 1497, 10.1093/ije/dyt179

Freeman, 2013, Power and sample size calculations for Mendelian randomization studies using one genetic instrument., Int J Epidemiol, 42, 1157, 10.1093/ije/dyt110

Burgess, 2014, Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome., Int J Epidemiol, 43, 922, 10.1093/ije/dyu005

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Burgess, 2011, Avoiding bias from weak instruments in Mendelian randomization studies., Int J Epidemiol, 40, 755, 10.1093/ije/dyr036

Burgess, 2013, Use of allele scores as instrumental variables for Mendelian randomization., Int J Epidemiol, 42, 1134, 10.1093/ije/dyt093

Bowden, 2015, Mendelian randomization with invalid instruments: Effect estimation and bias detection through Egger regression., Int J Epidemiol, 44, 512, 10.1093/ije/dyv080

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