Members of the Dlx‐and NKx2‐gene families are regionally expressed in the developing forebrain

Wiley - Tập 24 Số 10 - Trang 1385-1399 - 1993
Melanie Price1
1EMBL, Heidelberg, Germany

Tóm tắt

AbstractMembers of the vertebrate Dlx‐ and NKx2‐homeobox‐containing gene families exhibit closely related, comple‐mentary areas of gene expression in the developing forebrain. The expression domains and onset of gene transcription indicate that these genes may play a role in forebrain patterning, particularly in the diencephalon. In some cases, gene expression borders coincide with mor‐phological boundaries separating functional and anatomical regions of the forebrain suggesting that the rostral region of the neural tube may indeed arise from a segmented structure. © 1993 John Wiley & Sons, Inc.

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