Chảy máu tiêu hóa do thuốc gây ra

Der Internist - Tập 60 - Trang 597-607 - 2019
W. Fischbach1,2
1Gastroenterologie und Innere Medizin Aschaffenburg, Aschaffenburg, Deutschland
2Ehemals Medizinische Klinik II, Klinikum Aschaffenburg-Alzenau, Akademisches Krankenhaus der Universität Würzburg, Aschaffenburg, Deutschland

Tóm tắt

Chảy máu tiêu hóa là một sự kiện thường gặp và có thể đe dọa tính mạng, đặc biệt là ở người cao tuổi. Nguyên nhân chủ yếu thường do thuốc gây ra. Các loại thuốc có thể dẫn đến chảy máu tiêu hóa bao gồm chủ yếu là thuốc chống viêm không steroid như Diclofenac hoặc Ibuprofen, thuốc ức chế kết tập tiểu cầu như Acetylsalicylsäure, Clopidogrel hoặc Prasugrel, và các thuốc chống đông như các đối kháng vitamin K, Heparin hoặc các thuốc chống đông đường uống trực tiếp. Điều trị phối hợp, chẳng hạn như ức chế tiểu cầu kép hoặc sự kết hợp giữa ức chế kết tập tiểu cầu với chống đông, đi kèm với nguy cơ chảy máu cao hơn so với điều trị đơn thuần. Có các phương pháp dự phòng sơ cấp và thứ cấp như triệt tiêu Helicobacter pylori hoặc dùng thuốc hỗ trợ với thuốc ức chế bơm proton.

Từ khóa

#chảy máu tiêu hóa #thuốc #người cao tuổi #chống viêm không steroid #ức chế kết tập tiểu cầu #chống đông

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