Measurement of platelet aggregation, independently of patient platelet count: a flow‐cytometric approach

Journal of Thrombosis and Haemostasis - Tập 15 Số 6 - Trang 1191-1202 - 2017
Pernille Just Vinholt1, Henrik Frederiksen2, Anne‐Mette Hvas3, Ulrik Sprogøe4, Christian Nielsen4
1Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark
2Department of Hematology, Odense University Hospital, Odense, Denmark
3Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark
4Department of Clinical Immunology, Odense University Hospital, Odense, Denmark

Tóm tắt

Từ khóa


Tài liệu tham khảo

Franco, 2015, Platelets at the interface of thrombosis, inflammation, and cancer, Blood, 126, 582, 10.1182/blood-2014-08-531582

Hersh, 1965, Causes of death in acute leukemia: a ten‐year study of 414 patients from 1954–1963, JAMA, 193, 105, 10.1001/jama.1965.03090020019005

Slichter, 2010, Dose of prophylactic platelet transfusions and prevention of hemorrhage, N Engl J Med, 362, 600, 10.1056/NEJMoa0904084

Vinholt, 2014, An overview of platelet indices and methods for evaluating platelet function in thrombocytopenic patients, Eur J Haematol, 92, 367, 10.1111/ejh.12262

Cattaneo, 2013, Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the Platelet Physiology Subcommittee of SSC/ISTH, J Thromb Haemost, 11, 1183, 10.1111/jth.12231

De Cuyper, 2013, A novel flow cytometry‐based platelet aggregation assay, Blood, 121, e70, 10.1182/blood-2012-06-437723

Leinoe, 2004, Multiple platelet defects identified by flow cytometry at diagnosis in acute myeloid leukaemia, Br J Haematol, 127, 76, 10.1111/j.1365-2141.2004.05156.x

Leinoe, 2005, Prediction of haemorrhage in the early stage of acute myeloid leukaemia by flow cytometric analysis of platelet function, Br J Haematol, 128, 526, 10.1111/j.1365-2141.2004.05335.x

Psaila, 2011, Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia, J Thromb Haemost, 9, 2302, 10.1111/j.1538-7836.2011.04506.x

Swerdlow, 2008

Rodeghiero, 2010, ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders, J Thromb Haemost, 8, 2063, 10.1111/j.1538-7836.2010.03975.x

Lordkipanidze, 2014, Characterization of multiple platelet activation pathways in patients with bleeding as a high‐throughput screening option: use of 96‐well Optimul assay, Blood, 123, e11, 10.1182/blood-2013-08-520387

Rubak, 2015, Investigation of platelet function and platelet disorders using flow cytometry, Platelets, 27, 66, 10.3109/09537104.2015.1032919

Shattil, 1985, Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation, J Biol Chem, 260, 11107, 10.1016/S0021-9258(17)39154-8

Kuypers, 1990, Continuous cell activation is necessary for stable interaction of complement receptor type 3 with its counter‐structure in the aggregation response of human neutrophils, Eur J Immunol, 20, 501, 10.1002/eji.1830200307

Slichter, 2004, Relationship between platelet count and bleeding risk in thrombocytopenic patients, Transfus Med Rev, 18, 153, 10.1016/j.tmrv.2004.03.003

van Bladel, 2014, Functional platelet defects in children with severe chronic ITP as tested with 2 novel assays applicable for low platelet counts, Blood, 123, 1556, 10.1182/blood-2013-08-519686

Iyu, 2011, Mode of action of P2Y(12) antagonists as inhibitors of platelet function, Thromb Haemost, 105, 96, 10.1160/TH10-07-0482

Iyu, 2011, Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist, Arterioscler Thromb Vasc Biol, 31, 416, 10.1161/ATVBAHA.110.219501

Chackalamannil, 2008, Discovery of a novel, orally active himbacine‐based thrombin receptor antagonist (SCH 530348) with potent antiplatelet activity, J Med Chem, 51, 3061, 10.1021/jm800180e

Peter, 1998, Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (alphaIIbbeta3) inhibitors, Blood, 92, 3240, 10.1182/blood.V92.9.3240

Armstrong, 2012, GPIIb/IIIa inhibitors: from bench to bedside and back to bench again, Thromb Haemost, 107, 808, 10.1160/TH11-10-0727

Weber, 2001, Differential inhibition of adenosine diphosphate‐ versus thrombin receptor‐activating peptide‐stimulated platelet fibrinogen binding by abciximab due to different glycoprotein IIb/IIIa activation kinetics, Blood, 98, 1619, 10.1182/blood.V98.5.1619

Gawaz, 2000, Incomplete inhibition of platelet aggregation and glycoprotein IIb–IIIa receptor blockade by abciximab: importance of internal pool of glycoprotein IIb–IIIa receptors, Thromb Haemost, 83, 915, 10.1055/s-0037-1613921

Frelinger, 2015, Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP, Blood, 126, 873, 10.1182/blood-2015-02-628461

Soderstrom, 2016, The effect of centrifugation speed and time on pre‐analytical platelet activation, Clin Chem Lab Med, 54, 1913, 10.1515/cclm-2016-0079

Peters, 2003, Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study, Circulation, 108, 1682, 10.1161/01.CIR.0000091201.39590.CB

Cannon, 2010, Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double‐blind study, Lancet, 375, 283, 10.1016/S0140-6736(09)62191-7