Matched T cell repertoire analysis of peripheral blood and tumor-infiltrating lymphocytes (TILs) in early stage breast cancer (ESBC) patients (pts) treated with pre-operative cryoablation (cryo) and/or Ipilimumab (Ipi)

Journal for ImmunoTherapy of Cancer - Tập 2 - Trang 1-2 - 2014
David B Page1, Heather McArthur1, Zhiwan Dong2, Phillip Wong1, Ryan Emerson3, Zhenyu Mu2, Chunjun Zhao2, Christopher Comstock, Elizabeth Morris4, Elizabeth Comen1, Alan Kotin4, Janice Sung1, Edi Brogi1, Monica Morrow1, Stephen Solomon1, Virgilio Sacchini1, Majid Maybody1, Deirdre Neville, Adi Diab5, Padmanee Sharma, Harlan Robins6, Sujata Patil4, Jedd D Wolchok4, Clifford Hudis1, Larry Norton1, James Allison5, Jianda Yuan7
1Memorial Sloan Kettering Cancer Center, New York, USA
2Sloan Kettering Institute, New York, USA
3Adative Biotechnologies, Seattle, USA
4Memorial Sloan-Kettering Cancer Center, New York, USA
5MD Anderson Cancer Center, Houston, USA
6Fred Hutchinson Cancer Center, Seattle, USA
7Immune Monitoring Facility, Sloan Kettering Institute, New York, USA

Tài liệu tham khảo

Waitz R, Solomon S: Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy. Cancer Res. 72: 430-9. Diab A, McArthur H: A pilot study of preoperative (Pre-op), single-dose Ipilimumab (Ipi) and/or cryoablation (Cryo) in women (pts) with early-stage/resectable breast cancer (ESBC). ASCO Annual Meeting. 2014, Abs #1098, Chicago, IL Page D, Yuan J: T cell receptor (TCR) DNA deep sequencing to evaluate clonality of tumor-infiltrating lymphocytes (TILs) in early-stage breast cancer patients (pts) receiving preoperative cryoablation (cryo) and/or Ipilimumab (Ipi). ASCO Annual Meeting. 2014, Chicago, IL, , Abs #3021