MPSA short communications

Baumgartner, B. J., Harvey, R. J., Darlison, M. G., and Barnes, E. M., Jr. (1994).Mol. Brain Res. (in press). Bretcher, M. S., and Lutter, R. (1988).EMBO J. 8, 1341–1348. Calkin, P. A., and Barnes, E. M., Jr. (1994).J. Biol. Chem. 269, 1548–1553. Hablitz, J. R., Tehrani, M. H. J., and Barnes, E. M., Jr. (1989).Brain Res. 501, 332–338. Anderson, M. A., Cornish, E. C., Mau, S. L., Williams, E. G., Hoggart, R., Atkinson, A., Bonig, I., Grego, B., Simpson, R., Roche, P. J., Haley, J. D., Penschow, J. D., Niall, H. D., Tregear, G. W., Cochran, J. P., Crawford, R. J., and Clarke, A. E. (1986).Nature 321, 38–44. Cornish, E. C., Pettitt, J. M., Bonig, I., and Clarke, A. E. (1987).Nature 326, 99–102. Kawata, Y., Sakiyama, F., Hayashi, F., and Kyogoku, Y. (1990).Eur. J. Biochem. 187, 255–262. Kheyr-Pour, A., Bintrim, S. B., Ieoger, T. A., Remy, R., Hammond, S. A., and Kao, T. (1990).Sex. Plant Reprod. 3, 88–97. McClure, B. A., Haring, V., Ebert, P., Anderson, M. A., Simpson, R. J., Sakiyama, F., and Clarke, A. E. (1989).Nature 342, 955–957. Taylor, C. B., Bariola, P. A., DelCardyre, S. B., Raines, R. T., and Green, P. J. (1993).Proc. Natl. Acad. Sci. USA 90, 5118–5122. Hihara, J. (1993). InProtein Analysis Renaissance (Applied Biosystems, 7th Symposium Protein Society), p. 15. Nika, H., Tabanhfar, S., and Mattaliano, R. (1992). InNew Approaches in Sequence and Presequence Analysis (Applied Biosystems, 6th Symposium Protein Society), p. 29. Patterson, S. D., Hess, D., Yungwirth, T., and Aebersold, R. (1992).Anal. Biochem. 202, 193. Salnikow, J. (1986). In Wittmann-Liebold, B. (ed.),Advanced Methods in Protein Sequencing Analysis, p. 79. Clore, G. M., and Gronenborn, A. M. (1991).Science 252, 1390–1399. Clore, G. M., Appella, E., Yamada, M., Matsushima, K., and Gronenborn, A. M. (1990).Biochemistry 29, 1689–1696. Clore, G. M., Wingfield, P. T., and Gronenborn, A. M. (1991).Biochemistry 30, 2315–2323. Clore, G. M., Bax, A., Omichinki, J. G., and Gronenborn, A. M. (1994).Structure 2, 89–94. Lodi, P. J., Garrett, D. S., Kuzsweski, J., Tsang, M. L. S., Weatherbee, J. A., Leonard, W. J., Gronenborn, A. M., and Clore, G. M. (1994).Science (in press). Omichinski, J. G., Clore, G. M., Scaad, O., Felsenfeld, G., Trainor, C., Appella, E., Stahl, S. J., and Gronenborn, A. M. (1993).Science 261, 438–446. Argos, P. (1988).Nucleic Acids Res. 16, 9909–9916. Bairoch, A. (1992).Nucleic Acids Res. 20(Suppl.), 2013–2018. Bairoch, A., and Boekmann, B. (1992).Nucleic Acids Res. 20(Suppl.), 2019–2022. Degli Esposti, M., Crimi, M., and Venturoli, G. (1990).Eur. J. Biochem. 190, 207–219. Devereux, J., Haberli, P., and Smithies, O. (1984).Nucleic Acids Res. 12, 387–395. Etzold, T., and Argos, P. (1993a).CABIOS 9, 49–57. Etzold, T., and Argos, P. (1993b).CABIOS 9, 59–64. Gribskov, M., McLachlan, A. D., and Eisenberg, D. (1987).Proc. Natl. Acad. Sci. USA 84, 4355–4358. Kyte, J., and Doolittle, R. F. (1982).J. Mol. Biol. 157, 105–132. Persson, B., Krook, M., and Jörnvall, H. (1991).Eur. J. Biochem. 200, 537–543. Rao, J. K. M., and Argos, P. (1986).Biochim. Biophys. Acta 869, 197–214. Sipos, L., and von Heijne, G. (1993).Eur. J. Biochem. 213, 1333–1340. Vingron, M., and Argos, P. (1989).CABIOS 5, 115–121. Von Heijne, G. (1992).J. Mol. Biol. 225, 487–494. Yeates, T. O., Komiya, H., Rees, D. C., Allen, J. P., and Feher, G. (1987).Proc. Natl. Acad. Sci. USA 84, 6438–6442. Agostinis, P.,et al. (1992).J. Biol. Chem. 267, 9732–9737. Henzel, W. J.,et al. (1993).Proc. Natl. Acad. Sci. USA 90, 5011–5015. James, P.,et al. (1988).J. Biol. Chem. 263, 2905–2910. James, P.,et al. (1989).Nature 342, 90–92. Cannons, A. C., Barber, M. J., and Solomonson, L. P. (1993).J. Biol. Chem. 268, 3268–3271. Crawford, N. M., Smith, M., Bellismio, D., and Davis, R. W. (1988).Proc. Natl. Acad. Sci. USA 83, 6825–6828. Mathews, F. S. (1985).Prog. Biophys. Mol. Biol. 45, 1–56. Solomonson, L. P., and Barber, M. J. (1990).Annu. Rev. Plant Physiol. 41, 225–253. Birkbeck, J. C., Cassidy, R. T., Fagin, P. N., and Moddeman, W. E. (1987).Soc. Mech. Eng. MD 4, 15. Bumben, K. D., and Dev, S. B. (1988).Anal. Chem. 60, 1393. Moddeman, W. E., Collins, L. W., Wang, P. S., and Wittberg, T. N. (1980).Proc. 7th Int. Pyrotech. Symp. (Vail, CO)7, 408. Moddeman, W. E., Birkbeck, J. C., Bowling, W. C., Burke, A. R., and Cassidy, R. T. (1989).Ceramic Eng. Sci. 10, 1403. Wittberg, T. N., Svisco, C. A., and Moddeman, W. E. (1980a).Corrosion 36, 517. Wittberg, T. N., Moddeman, W. E., Collins, L. W., and Wang, P. S. (1980b).Levide, Los Crouches Mines (Suppl.) 201, 562. Worley, C. M., Vannet, M. D., Ball, G. L., and Moddemann, W. E. (1987).Surface Interface Anal. 10, 273. Dayhoff, M. O. (1976).Fed. Proc. 33, 2314–2316. Dayhoff, M. O., McLaughlin, P. J., Barker, W. C., and Hunt, L. T. (1975).Naturwissenschaften 62, 154–161. Sander, C., and Schneider, R. (1991).Proteins: Struct. Funct. Genet. 9, 56–68. Gabius, H., Engelhardt, R., Graupner, G., and Cramer, F. (1986). In Bog-Hansen, T. C., and van Driessche, E. (eds.),Lectins: Biology, Biochemistry, Clinical Biochemistry (de Gruyter, Berlin), pp. 237–242. Kolb-Bachofen, V. (1986). In Bog-Hansen, T. C., and van Driessche, E. (eds.),Lectins: Biology, Biochemistry, Clinical Biochemistry (de Gruyter, Berlin), pp. 197–206. Miller, C. A., and Costa, M. (1989).Mol. Toxicol. 2, 11–26. Stein, G. S., and Kleinsmith, L. J., eds. (1979).Chromosomal Proteins and Their Role in the Regulation of Gene Expression (Academic Press, New York). Sugiyama, M., Patierno, S. R., Catoni, O., and Costa, M. (1986).Mol. Pharmacol. 29:606–613. Tsapokos, M. J., Hampton, T. H., and Watterhahn, K. E. (1991).Cancer Res. 43:5662–5667. Fontana, A., and Gross, E. (1986). In Darbre, A. (ed.),Practical Protein Chemistry-A Handbook (Wiley, New York), pp. 94–95. Huang, H. V., Bond, M. W., Hunkapiller, M. W., and Hood, L. E. (1983).Meth. Enzymol. 91, 318–324. Ozols, J., and Gerard, C. (1977).J. Biol. Chem. 252, 5986–5989. Savige, W. B., and Fontana, A. (1977).Meth. Enzymol. 47, 459–469. Dwek, R. (1993).FASEB. J. 7, 1330. Fukuda, M., and Kobata, A., eds. (1993).Glycobiology. A Practical Approach (IRL Press, London). Hardy, M., Townsend, R. R.,et al. (1988).Anal. Biochem. 170, 54. Suzuki, S., Kakehi, K.,et al. (1992).Anal. Biochem. 205, 227. Hunt, D., Yates III, J. R., Shabanowitz, J., Winston, S., and Hauer, C. R. (1986).Proc. Nad. Acad. Sci. USA 83, 6233–6237. Murthy, A. S. N., Mains, R. E., and Eipper, B. A. (1986).J. Biol. Chem. 261, 1825–1822. Johnson, B. A., and Aswad, D. W. (1990). In Paik, W. K., and Kim, S. (eds.),Protein Methylation (CRC Press, Boca Raton, Florida), pp. 195–210. Lindquist, J. A., and McFadden, P. N. (1994).J. Protein Chem. 13, 23–30. Lowenson, J. D., and Clarke, S. (1991).J. Biol. Chem. 266, 19396–19406. Ota, I. M., and Clarke, S. (1990). In Paik, W. K., and Kim, S. (eds.),Protein Methylation (CRC Press, Boca Raton, Florida), pp. 179–194. Chait, B.,et al. (1992). 40th ASMS Conference, Washington D.C. Tsugita, A.,et al. (1992).Eur. J. Biochem. 206, 691–696. Bergman, T., and Jörnvall, H. (1987).Eur. J. Biochem. 169, 9–12. Egyhazi, E., Stigare, J., Holst, M., and Pigon, A. (1991).Mol. Biol. Rep. 15, 65–72. Gardell, S. J., Craik, C. S., Clauser, E., Goldsmith, E. J., Stewart, C. B., Graf, M., and Rutter, W. J. (1988).J. BIol. Chem. 263, 17828–17836. Hermansen, L. F., Bergman, T., Jörnvall, H., Husby, G., Ranløv, I., and Sletten, K. (1994).Eur. J. Biochem. (submitted). Oppezzo, O., Ventura, S., Bergman, T., Vendrell, J., Jörnvall, H., and Avilés, F. X. (1994).Eur. J. Biochem. (in press). Tsunasawa, S., and Hirano, H. (1993). In Imahori, K., and Sakiyama, F. (eds.),Methods in Protein Sequence Analysis (Plenum Press, New York), pp. 45–53. Danielsson, O., and Jörnvall, H. (1993).Proc. Natl. Acad. Sci. USA 89, 9247–9251. Danielsson, O., Atrian, S., Luque, T., Hjelmqvist, L., Gonzàlez-Durate, R., and Jörnvall, H. (1994).Proc. Natl. Acad. Sci. USA 91 (in press). Persson, B., Bergman, T., Keung, W. M., Waldenström, U., Homquist, B., Vallee, B. L., and Jörnvall, H. (1993).Eur. J. Biochem. 216, 49–56. Atkinson, R. A., Saudek, V., Huggins, J. P., and Pelton, J. T. (1991).Biochemistry 30, 9387–9395. Dorow, D. S., Devereux, L., Dietzsch, E., and De Krester, T. A. (1993).Eur. J. Biochem. 213, 701–710. Ezoe, K., Lee, S.-T., Strunk, K. M., and Spritz, R. A. (1994).Oncogene 9, 935–938. Gout, I., Dhand, R., Fry, M. J., Panayotou, G., Das, P., Truong, O., Totty, N., Hsuan, J., Booker, G. W., Campbell, I. D., and Waterfield, M. D. (1993).Cell 75, 25–36. Koch, C. A., Anderson, D., Moran, M. F., Ellis, C., and Pawson, T. (1991).Science 252, 668–674. Samule, K. P., Hodge, D. R., Chen, Y.-M., and Papas, T. S. (1991).AIDS Res. Hum. Retroviruses 7, 697–706. Bode, W., Reinemer, P., Huber, R., Kleine, T., Schnierer, S., and Tschesche, H. (1994).EMBO J. 13 (in press). Knäuper, V., Krämer, S., Reinke, H., and Tschesche, H. (1990).Eur. J. Biochem. 189, 295–300. Reinemer, R., Grams, F., Huber, R., Kleine, T., Schnierer, S., Piper, M., Tschesche, H., and Bode, W. (1994).FEBS Lett. 338, 227–233. Schnierer, S., Kleine, T., Gote, T., Hillemann, A., and Tschesche, H. (1993).Biochem. Biophys. Res. Commun. 191, 319–326. Van Wart, H., and Birkedal-Hansen, H. (1990).Proc. Natl. Acad. Sci. USA 87, 5578–5582. Southan, C. (1993).Protein Sci. 2, 105. Attwood, T. K., and Findlay, J. B. C. (1994).Protein Eng. 7, 195–203. Bairoch, A., and Boeckmann, B. (1991).Nucleic Acids Res. 19 (Suppl.), 2247–2249. Barton, G. J., and Sternberg, M. J. E. (1990).J. Mol. Biol. 212, 389–402. Bleasby, A. J., and Wootton, J. C. (1990).Protein Eng. 3, 153–159. Burks, C., Fickett, J. W., Goad, W. B., Kanehisa, M., Lewitter, F. I., Rindone, W. P., Swindell, C. D., Tung, C.-S., and Bilofsky, H. S. (1986).Comput. Appl. Biosci. 1, 225–233. Fickett, J. W. (1986).Trends Biochem. Sci. 11, 190. Flower, D. R., North, A. C. T., and Attwood, T. K. (1991).Biochem. Biophys. Res. Commun. 180, 65–74. Flower, D. R., North, A. C. T., and Attwood, T. K. (1993).Protein Sci. 2, 753–761. George, D. G., Barker, W. C., and Hunt, L. T. (1986).Nucleic Acids Res. 14, 11–15. Lipman, D. J., and Pearson, W. R. (1985).Science 227, 1435–1441. Namboodiri, K., Pattabiraman, N., Lowrey, A., Gaber, B., George, D. G., and Barker, W. C. (1989).PIR Newsl. 8, 5. North, A. C. T. (1989).Int. J. Biol. Macromol. 11, 56–58. Parry-Smith, D. J., and Attwood, T. K. (1991).Comput. Appl. Biosci. 7, 233–235. Aitken, A. (1990). InIdentification of Protein Consensus Sequences (Ellis-Horwood, Chichester/Simon and Schuster, New York), pp. 1–167. Aitken, A., Collinge, D. B., van Heusden, G. P. H., Roseboom, P. H., Isobe, T., Rosenfeld, G., and Soll, J. (1992).Tends Biochem. Sci. 17, 498–501. Fu, H., Coburn, J., and Collier, R. J. (1993).Proc. Natl. Acad. Sci. USA 90, 2320–2324. Kay, I., and Mallet, A. I. (1993). Abstract, 20th British Mass Spectrometry Society Meeting, Canterbury, U.K., pp. 203–206. Ichimura, T., Isobe, T., Okuyama, T., Yamauchi, T., and Fujisawa, H. (1987).FEBS Lett. 219, 79–82. Leffers, H., Madsen, P., Rassmussen, H. H., Honore, B., Andersen, A. H., Walbum, E., Vandekerckhove, J., and Celis, J. E. (1993).J. Mol Biol. 231, 982–998. Martin, H., Patel, Y., Jones, D., Howell, S., Robinson, K., and Aitken, A. (1993).FEBS Lett. 331, 296–303. Martin, H., Rostas, J., Patel, Y., and Aitken, A. (1994).J. Neurochem. (in press). Morgan, A., and Burgoyne, R. D. (1992).Nature 355, 833–836. Nielsen, P. J. (1991).Biochim. Biophys. Acta 1088, 425–428. Patel, Y., Martin, H., Howell, S., Jones, D., Robinson, K., and Aitken, A. (1994).Biochim. Biophys. Acta (in press). Prasad, G. L., Valverius, E. M., McDuffie, E., and Cooper, H. L. (1992).Cell Growth Differentiation 3, 507–513. Robinson, K., Jones, D., Patel, Y., Martin, H., Madrazo, J., Martin, S., Howell, S., Elmore, M., Finnen, M., and Aitken, A. (1994).Biochem. J. (in press). Roseboom, P. H., Weller, J. L., Namboodiri, M. A. A., Toker, A., Aitken, A., and Klein, D. C. (1992).FASEB. J. 6, 1516. Taylor, S. S. (1992).Trends Biochem. Sci. 17, 84–89. Toker, A., Sellers, L. A., Patel, Y., Harris, A., and Aitken, A. (1992).Eur. J. Biochem. 206, 453–461. Aebersold, R. (1993).Curr. Opin. Biotechnol. 4, 412–419. Collins, F., and Galas, D. (1993).Science 262, 43–46. Hess, D., Covey, T. C., Winz, R., Brownsey, R., and Aebersold, R. (1993).Protein Sci. 2, 1342–1351. Winz, R., Hess, D., Aebersold, R., and Brownsey, R. W. (1994).J. Biol. Chem. (in press). Aebersold, R., Bures, E. J., Namchuk, M., Goghari, M. H., Shushan, B., and Covey, T. C. (1992).Protein Sci. 1, 494–503. Edman, P.(1950).Acta Chem. Scand. 4, 283–290. Scheraga, H. A. (1992). In Lipikowitz, K. B., and Boyd, D. B. (eds.),Reviews in Computational Chemistry, Vol. 3 (VCH, New York) pp. 73–142. Scheraga, H. A. (1993). In Van Gunsteren, W. F., Weiner, P. K., and Wilkinson, A. J. (eds.),Computer Simulation of Biomolecular Systems. Theoretical and Experimental Applications, Vol. 2 (ESCOM, Leiden), pp. 213–248. Brown, M. S., and Goldstein, J. L. (1986). A receptor-mediated pathway for cholesterol homeostasis,Science 234, 34. Chen, S.-H., Yang, C.-Y., Che, P. F., Setzer, D., Tanimura, M., Li, W.-H., Gotto, A. M., Jr., and Chan, L. (1986). The complete cDNA and amino acid sequence of human apolipoprotein B-100,J. Biol. Chem. 261, 12918. Goldstein, J. L., Ho, Y. K., Basu, S. K., and Brown, M. S. (1979). Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition,Proc. Natl. Acad. Sci. USA 76, 333. Henriksen, T., Mahoney, E. M., and Steinberg, D. (1983). Enhanced macrophage degradation of biologically modified low density lipoprotein,Arteriosclerosis 3, 149. Knott, T. J., Pease, R. J., Powell, L. M., Wallis, S. C., Rall, S. C., Jr., Innerarity, T. L., Blachart, B., Taylor, W. H., Marcel, Y. L., Milne, R. W., Johnson, D., Fuller, M., Lusis, A. J., McCarthy, B. J., Mahley, R. W., Levy-Wilson, B., and Scott, J. L. (1986). Complete protein sequence and identification of structural domains of human apoliproprotein B,Nature 323, 734. Steinbrecher, U. P., Parthasarathy, S., Leake, D. S., Witztum, J. L., and Steinberg, S. (1984). Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids,Proc. Natl. Acad. Sci. USA 81, 3883. Yang, C. Y.-Y., Chen, S.-H., Gianturco, S. H., Bradley, W. A., Sparrow, J. T., Tanimura, M., Li, W. H.-H., Sparrow, D. A., DeLoof, H., Rosseneus, M., Lee, F.-S., Gu, Z.-W., Gotto, A. M., Jr., and Chan, L. (1986). Sequence, structure, receptor biding domains and internal repeats of human apolipoprotein B-100,Nature 323, 738. Chang, J. Y., Creaser, E. H., and Bentley, K. W. (1976).Biochem. J. 153, 607–611. Edman, P., and Begg, G. (1967).Eur. J. Biochem. 1, 80–91. Haniu, M., and Shively, J. E. (1988).Anal. Biochem. 173, 296–306. Hewick, R. M., Hunkapiller, M. W., Hood, L. E., and Dreyer, W. J. (1981).J. Biol. Chem. 256 (15), 7990–7997. Maeda, H., Ishida, N., Kawauchi, H., and Tuzimura, K. (1969).J. Biochem. 65(5), 777–783. Otsukda, K., Terabe, S., and Ando, T. (1985).J. Chromatog.,332, 219–226. Shively, J. E., Miller, P., and Ronk, M. (1987).Anal. Biochem. 163, 517–529. Totty, N. F., Waterfield, M. D., and Hsuan, J. J. (1992).Protein Sci. 1, 1215–1224. Waldron, K. C., and Dovichi, N. J. (1992).Anal. Chem. 64(13), 1396–1399. Cleveland, D. W., Fisher, S. G., Kirschner, M. W., and Laemmli, U. K. (1977).J. Biol. Chem. 252, 1102–1106. Kennedy, T. E., Gawinowicz, M. A., Barzilai, A., Kandel, E. R., and Sweatt, J. D. (1988).Proc. Natl. Acad. Sci. USA 85, 7008–7012. Omori, A. (1990).J. Protein Chem. 9, 250–251. Biesecker, G., and Müller-Eberhard, H. J. (1980).J. Immunol. 124, 1291–1296. Chakravarti, D. N., Chakravarti, B., Parra, C. A., and Müller-Eberhard, H. J. (1989).Proc. Natl. Acad. Sci. USA 86, 2799–2803. Dankert, J. R., Shiver, J. W., and Esser, A. F. (1985).Bioechemistry 24, 2754–2762. DiScipio, R. G., and Hugli, T. E. (1989).J. Biol. Chem. 264, 16197–16206. Haefliger, J. A., Jenne, D., Stanley, K. K., and Tschopp, J. (1987).Biochem. Biophys. Res. Commun. 149, 750–754. Haefliger, J. A., Tschopp, J., Vial, N., and Jenne, D. E. (1989).J. Biol. Chem. 264, 18041–18051. Hess, D., Schaller, J., and Rickli, E. E. (1991).Biochemistry 30, 2827–2833. Savage, C. R., Hsah, J. H., and Cohen, S. (1973).J. Biol. Chem. 248, 7669–7672. Sim, R. B., Day, A. J., Moffatt, B. E., and Fontaine, M. (1993).Meth. Enzymol. 223, 13–35. Stanley, K. K., Kocher, H. P., Luzio, J. P., Jackson, P., and Tschopp, J. (1985).EMBO J. 4, 375–382. Sueyoshi, T., Miyata, T., Iwanaga, S., Toyo'oka, T., and Imai, K. (1985).J. Biochem. 97, 1811–1813. Bubis, J., and Khorana, H. G. (1990).J. Biol. Chem. 265, 12995–12999. Conklin, B. R., and Bourne, H. R. (1993).Cell 73, 631–641. Noel, J. P., Hamm, H. E., and Sigler, P. B. (1993).Nature 366, 654–663. Bailey, J. M., Nikfarjam, F., Shenoy, N. R., and Shively, J. E. (1992).Protein Sci. 1, 1622–1633. Boyd, V. L., Bozzini, M., Zon, G., Noble, R. L., and Mattaliano, R. J. (1992).Anal. Biochem. 206, 344–352. Inglis, A. S., Duncan, M. W., Adams, P., and Tseng, A. (1992).J. Biochem. Biophys. Meth. 25, 163–171. Reim, D. F., and Speicher, D. W. (1993).Anal. Biochem. 214, 87–95. Shenoy, N. R., Shively, J. E., and Bailey, J. M. (1993).J. Protein Chem. 12, 195–205. Stark, G. R. (1968).Biochemistry 7, 1796–1807. Miyatake, N., Kamo, M., Satake, K., Uchiyama, Y., and Tsugita, A. (1993).Eur. J. Biochem. 212, 785–789. Simpson, R. J., Tsugita, A., Celis, J. E., Garrels, J. I., and Mewes, H. W. (1992).Electrophoresis 13, 1055–1061. Tsugita, A., Kawakami, T., Uchiyama, Y., Kamo, M., Miyatake, N., and Nozu, Y. (1994).Electrophoresis (in press). Biemann, K. (1987).Biomed. Environ. Mass Spectrom. 16, 99–111. Tsugita, A., Takamoto, K., and Satake, K. (1992a).Chem. Lett. 1992, 235–238. Tsugita, A., Takamoto, K., Iwadate, H., Kamo, M., and Satake, K. (1992b). In Matsuo, T. (eds.),Biological Mass Spectrometry (San-ei, Kyoto), pp. 242–243. Tsugita, A., Takamoto, K., Iwadate, H., Kamo, M., Miyatake, N., and Satake, K. (1993). In Imahori, K., and Sakiyama, F. (eds.),Methods in Protein Sequence Analysis (Plenum Press, New York), pp. 55–62. Bischof, O., Kruft, V., and Wittmann-Liebold, B. (1994). (Submitted). Kerlavage, A. R., and Coopermann, B. S. (1986).Biochemistry 25, 8002–8010. Nicholson, N. W., Hall, C. C., Strycharz, W. A., and Cooperman, B. S. (1982).Biochemistry 21, 3797–3808. Baker, C. S., Corbett, J. M., May, A. J., Yacoub, M. H., and Dunn, M. J. (1992).Electrophoresis 13, 723–726. Benndorf, R., Kraft, R., Otto, A., Stahl, J., Böhm, H., and Bielka, H. (1988).Biochem. Int. 17, 225–234. Benndorf, R., Hayess, K., Stahl, J., and Bielka, H. (1992).Biochim. Biophys. Acta 1136, 203–207. Engel, K., Knauf, U., and Gaestel, M. (1991).Biomed. Biochem. Acta 50, 1065–1071. Fernandez, J., DeMott, M., Atherton, D., and Mische, Sh. M. (1992).Anal. Biochem. 201, 255–264. Gernold, M., Knauf, U., Gaestel, M., Stahl, J., and Kloetzel, P.-M. (1993).Dev. Genet. 14, 103–111. Horwitz, J. (1992).Proc. Natl. Acad. Sci. USA 89, 10449–10453. Jungblut, P., Eckerskorn, C., Lottspeich, F., and Klose, J. (1990).Elektrophoresis 11, 581–588. Jungblut, P., Dzionara, M., Klose, J., and Wittmann-Liebold, B. (1992).J. Prot. Chem. 11, 603–612. Jungblut, P., Otto, A., Zeindel-Eberhart, E., Pleissner, K. P., Knecht, M., Regitz-Zagrosek, V., Fleck, E., and Wittmann-Liebold, B. (1994).Electrophoresis 15(5) (in press). Kato, K., Shinohara, H., Goto, S., Inaguma, Y., Morishita, R., and Asano, T. (1992).J. Biol. Chem. 267, 7718–7725. Klemenz, R., Frohli, E., Steiger, R. H., Schafer, R., and Aoyama, A. (1991).Proc. Natl. Acad. Sci. USA 88, 3652–3656. Kose, J. (1973).Humangenetik 26, 231–243. Knecht, M., Regitz-Zagrosek, V., Pleissner, K. P., Jungblut, P., Hildebrandt, and Fleck, E. (1994).Eur. Heart. J. (in press). Landry, J., Lambert, H., Zhou, M., Lavoie, J. N., Hickey, E., Weber, L. A., and Anderson, C. W. (1992).J. Biol. Chem. 267, 794–803. Oesterreich, S., Benndorf, R., and Bielka, H. (1990).Biomed. Biochim. Acta 49, 219–226. Rasmussen, H. H., Van Damme, J., Puype, M., Gesser, B., Celis, J. E., and Vandekerckhove, J. (1991).Electrophoresis 12, 873–882. Arndt, E., Krömer, W., and Hatakeyama, T. (1990).J. Biol. Chem. 265, 3034–3039. Hatakeyama, T., and Kimura, M. (1988).Eur. J. Biochem. 172, 703–711. Studier, F. W., Rosenberg, A. H., Dunn, J. J., and Dubendorff, J. W. (1990).Meth. Enzymol. 185, 60–89. Von Böhlen, K., Makowski, I., Hansen, H. A. S., Bartels, H., Berkovitch-Yellin, Z., Zaytzev-Bashan, A., Meyer, S., Paulke, C., Franceschi, F., and Yonath, A. (1991).J. Mol. Biol. 222, 11–15. Wittmann, H. G. (1986). In Hardesty, B., and Kramer, G. (eds.),Structure, Function and Genetics of Ribosomes, (Springer-Verlag, Berlin), pp. 1–27. Brimacombe, R. (1991).Biochimie 73, 927–936. Golden, B. L., Hoffman, D. W., Ramankrishnan, V., and White, S. W. (1993).Biochemistry 32, 12812–12820. Maly, P., Rinke, J., Ulmer, E., Zwieb, C., and Brimacombe, R. (1980).Biochemistry 19, 4179–4188. Möller, K., Zwieb, C., and Brimacombe, R. (1978).J. Mol. Biol. 126, 489–506. Traut, R. R., Bollen, A., Sun, T. T., Hershey, J. W. B., Sundberg, J., and Pierce, L. R. (1973).Biochemistry 12, 3266–3272. Wower, I., Wower, J., Meinke, M., and Brimacombe, R. (1981).Nucleic Acids Res. 9, 4285–4302. Beckert, V., Dettmer, R., and Bernhardt, R. (1994).J. Biol. Chem. 269, 2568–2573. Coghlan, V. M., and Vickery, L. E. (1991).J. Biol. Chem. 266, 18606–18612. Driscoll, W. J., and Omdahl, J. L. (1986).J. Biol. Chem. 261, 4122–4125. Gener, L. M., O'Brien, P., Stonehuerner, J., and Millett, F. (1984).J. Biol. Chem. 259, 2155–2160. Matocha, M. F., and Waterman, M. R. (1985).J. Biol. Chem. 260, 12259–12265. Miura, S., and Ichikawa, Y. (1991).J. Biol. Chem. 266, 6252–6258. Taniguchi, T., and Kimura, T. (1975).Biochemistry 14, 5573–5578. Taniguchi, T., and Kimura, T. (1976).Biochemistry 15, 2849–2853. Ulhmann, H., Beckert, V., Schwarz, D., and Bernhardt, R. (1992).Biochem. Biophys. Res. Commun. 188, 1131–1138. Fox, O. R., Evans, A. P., and Dobson, M. C. (1986).Nature 320, 192–194. Mizutani, R., Schimada, I., Ueno, Y., Yoda, M., Kumagi, H., and Arata, Y. (1992).Biomed. Biophys. Res. Commun. 182, 966–973. Roder, H., Elove, A. G., and Englander, S. W. (1988).Nature 335, 700–704. Schmid, X. F., Grafl, R., Wrba, A., and J. Beinterma, J. (1986).Proc. Natl. Acad. Sci. USA 83, 872–876. Brenner, S., and Lerner, R. A. (1992).Proc. Natl. Acad. Sci. USA 89 5381–5383. Bunin, B. A., and Ellman, J. A. (1992).J. Am. Chem. Soc. 114, 10997–10998. Cho, C. Y.,et al. (1993).Science 261, 1303–1305. Kerr, J. M., Banville, S. C. and Zuckermann, R. N. (1993).J. Am. Chem. Soc. 115, 2529–2531. Lam, K.,et al. (1991).Nature 354, 82–84. Lebl, M.,et al. (1994). In Crabb, J. W. (ed.),Techniques in Protein Chemistry (Academic Press, Orlando, Florida), pp. 541–548. Moos, W. H.,et al. (1993).Annu. Rep. Med. Chem. 28, 315–324. Needels, M. C.,et al. (1993).Proc. Natl. Acad. Sci. USA 90, 10700–10704. Nikolaiev, V.,et al. (1993).Peptide Res. 6, 161–170. Ohlmeyer, M. H.,et al. (1993).Proc. Natl. Acad. Sci. USA 90, 10922–10926. Simon, R.,et al. (1992).Proc. Natl. Acad. Sci. USA 89, 9367–9371. Vagner, J.,et al. (1994). In Epton, R. (ed.),Innovation and Perspectives in Solid Phase Synthesis, (in press). Afeyan, N. B., Gordon, N. F., Mazsaroff, I., Varady, L., Fulton, S. P., Yang, Y. B., and Regnier, F. E. (1990).J. Chromatogr. 519, 1–29. Kalghatgi, K., and Horváth, C. (1987).Chromatog. 398, 335–339. Kato, Y., Kitamura, T., Mitsui, A., and Hashimoto, T. (1987).J. Chromatog. 398, 327–334. Nice, E. C., and Simpson, R. J. (1989).J. Pharm. Biomed. Anal. 7/9, 1039–1053. Regnier, F. E. (1991).Nature 350, 635–635. Rozing, G., and Goetz, H. (1989).J. Chromatogr. 476, 3–19. Unger, K. K., Jilge, G., Kinkel, J. N., and Hearn, M. T. W. (1986).J. Chromatogr. 359, 61–72. Argos, P. (1990). An investigation of oligopeptides linking domains in protein tertiary structures and possible candidates for general gene fusion,J. Mol. Biol. 211, 943–958. Karplus, P. A., and Schulz, G. E. (1985). Prediction of chain flexibility in proteins,Naturwissenschaften 72, 212–213. Kato, A., Komatsu, K., Fujimoto, K., and Kobayashi, K. (1985).J. Agric. Food Chem. 33, 931–934. Le Meste, M., Colas, B., Simatos, D., Closs, B., Courthaudon, J.-L., and Lorient, D. (1990). Contribution of protein flexibility to the foaming properties of casein,J Food Sci. 55, 1445–1447. Seffens, W. S. (1989). Sequence and expression of phylogenetically conserved carrot gene, Dc3: A marker of embryogenic potential, Ph.D. Dissertation, Texas A&M University, College Station, Texas. Tainer, J. A., Getzoff, E. D., Alexander, H., Houghten, R. A., Olson, A. J., Lerner, R. A., and Hendrickson, W. A. (1984). The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein,Nature 312, 127–134. Vihinen, M. (1987). Relationship of protein flexibility to thermostability,Protein Eng. 1, 477–480. Westhof, E., Altschuh, D., Moras, D., Bloomer, A. C., Mondragon, A., Klug, A., and Van Regenmortel, M. H. (1984). Correlation between segmental mobility and the location of antigenic determinants in proteins,Nature 311, 123–126. Clarke, S. (1992). Protein isoprenylation and methylation at carboxyl-terminal cysteine residues.Annu. Rev. Biochem. 61, 355–386. Davisson, V. J., and Poulter, C. D. (1993). Farnesyl-diphosphate synthase. Interplay between substrate topology, sterochemistry, and regiochemistry in electrophilic alkylations,J. Am. Chem. Soc. 115, 1245–1260. Mayer, M. P., Prestwich, G. D., Dolence, J. M., Bond, P. D., Wu, H.-Y., and Pulter, C. D. (1993). Protein farnesyltransferase: Production inEscherichia coli and immunoaffinity purification of the heterodimer fromSaccharomyces cerevisiae, Gene 132, 41–47. Pompliano, D. L., Gomez, R. P., and Anthony, N. J. (1992). Intramolecular fluorescence enhancement: A continuous assay of ras farnesyl: protein transferase,”J. Am. Chem. Soc. 114, 7945–7946. Brown, J. R. (1977). In Rosener, S.,et al. (eds.),Albumin Structure, Function and Uses (Pergamon Press, Oxford), pp. 27–51. Kanaya, E., Ishihara, K., Tsunasawa, S., Nokihara, K., and Kikuchi, K. (1993).Biochem J. 292, 469–476. Nishimura, K., Harada, K., Nakayama, M., Sugii, A., Uji, Y., and Okabe, H. (1992).J. Anal. Biosci. 15, 200–205. Nokihara, K., Morita, N., Yamaguchi, M., and Watanabe, T. (1992a).Anal. Lett. 25, 513–533. Nokihara, K., Kondo, J., Yamamoto, R., Ueda, A., and Hazama, M. (1992b).J. Protein Chem. 11, 365. Sumi, A., Ohtani, W., Kobayashi, K., Ohmura, T., Yokoyama, K., Nishida, M., and Suyama, T. (1993).In Rivat, C.,et al. (eds.),Biotechnology of Blood Proteins (INSERM/John Libbey Eurotext), vol. 227, pp. 293–298. Fraenkel-Conrat, H. (1983).J. Toxicol. 2, 205–221. Shipolini, R. A., Callewaert, G. L., Cottrell, R. C., and Vernon, C. A. (1971).FEBS Lett. 17, 39–40. Verheij, H. M., Slotboom, A. J., and de Haas, G. H. (1981).Rev. Physiol. Biochem. Pharmacol. 91, 91–203. Atassi, M. Z. (1975).Immunochemistry 12, 423–428. Atassi, M. Z. (1978).Immunochemistry 15, 909–936. Atassi, M. Z. (1984).Eur. J. Biochem. 145, 1–20. Atassi, M. Z., McDaniel, C. S., and Manshouri, T. (1988).J. Protein Chem. 7, 655–666. Changeux, J. P., Devillers-Thiery, A., and Chemouilli, P. (1984).Science 225, 1335–1345. David, C. S., and Atassi, M. Z. (1982).Adv. Exp. Med. Biol. 150, 97–126. Haggerty, J. G., and Froehner, S. C. (1981).J. Biol. Chem. 256, 8294–8297. Endo, T., and Tamiya, N. (1987).Pharmacol. Ther. 334, 403–451. McCarthy, M. P., Earnest, J. P., Young, E. T., Choe, S., and Stroud, R. M. (1986).Annu. Rev. Neurosci. 9, 383–413. McDaniel, C. S., Manshouri, T., and Atassi, M. Z. (1987).J. Protein Chem. 6, 455–461. Mulac-Jericevic, B., and Atassi, M. Z. (1986).FEBS Lett. 199, 68–74. Mulac-Jericevic, B., and Atassi, M. Z. (1987a).Biochem. J. 248, 847–852. Mulac-Jericevic, B., and Atassi, M. Z. (1987b).J. Protein Chem. 6, 365–373. Mulac-Jericevic, B., Manshouri, T., Yokoi, T., and Atassi, M. Z. (1988).J. Protein Chem. 7, 173–177. Okuda, K., Twining, S. S., David, C. S., and Atassi, M. Z. (1979).J. Immunol. 123, 182–188. Ruan, K. H., Spurlino, J., Quiocho, F. A., and Atassi, M. Z. (1990).Proc. Natl. Acad. Sci. USA 87, 6156–6160. Ruan, K. H., Stiles, B. G., and Atassi, M. Z. (1991).Biochem. J. 274, 849–854. Twining, S. S., David, C. S., and Atassi, M. Z. (1981).Mol. Immunol. 18, 447–450. Weber, M., and Changeux, J. (1974).Mol. Pharmacol. 10, 1–4. Air, G. M., and Laver, W. G. (1990). In Van Regenmortel, M. H. V., and Neurath, A. R. (eds.),Immunochemistry of Viruses, II. The Basis for Serodiagnosis and Vaccines (Elsevier, Amsterdam), pp. 171–216. Atassi, M. Z. (1975).Immunochemistry 12, 423–438. Atassi, M. Z. (1978).Immunochemistry 15, 909–936. Atassi, M. Z. (1984).Eur. J. BIochem. 145, 1–20. Atassi, M. Z., and Kurisaki, K. I. (1984).Immunol. Commun. 13, 539–551. Atassi, M. Z., and Kurisaki, J. I. (1986).Protides Biol. Fluids 34, 157–160. Atassi, M. Z., Torres, J. V., and Wyde, P. R. (1989).Adv. Exp. Med. Biol. 251, 49–63. Lamb, A. R. (1989). In Krug, R. M. (ed.),The influenza Viruses (Plenum Press, New York), pp. 1–87. Scheid, A., and Choppin, P. W. (1974).Virology 57, 475–490. Shaw, M. W., Arden, N. H., and Maassab, H. F. (1992).Clin. Microbiol. Rev. 5, 115–118. Torres, J. V., Wyde, P. R., and Atassi, M. Z. (1988).Immunol. Lett. 19, 49–54. Webster, R. G., Laver, W. G., and Schild, G. C. (1982).Nature 296, 115–118. Wiley, D. C., and Skehel, J. J. (1987).Annu. Rev. Biochem. 56, 365–394. Ballard, K. D., and Gaskell, S. J. (1992).J. Am. Chem. Soc. 114, 64. Ballard, K. D., and Gaskell, S. J. (1993).J. Am. Soc. Mass Spectrom. 4, 477–481. Biemann, K. (1990). In McCloskey, J. A. (ed.),Mass Spectrometry (Academic Press, New York), pp. 455–479. Burlet, O., Orkiszewski, R. S., Ballard, K. D., and Gaskell, S. J. (1992a).Rapid Commun. Mass Spectrom. 6, 658–662. Burlet, O., Yang, C.-Y., and Gaskell, S. J. (1992b).J. Am. Soc. Mass Spectrom. 3, 337–344. Fenn, J. B., Mann, M., Chin Kai Meng, Shek Fu Wong, and Whitehouse, C. M. (1990).Mass Spectrom. Rev. 9, 37–70. Henzel, W. J., Billeci, T. M., Stults, J. T., Wong, S. C., Grimley, C., and Watanabe, C. (1993).Proc. Natl. Acad. Sci. USA 90, 5011–5015. Hines, W. M., Falick, A. M., Burlingame, A. L., and Gibson, B. W. (1992).J. Am. Soc. Mass Spectrom. 3, 326–336. Huang, E. C., and Henion, J. D. (1990).J. Am. Soc. Mass Spectrom. 1, 158–165. Huberty, M. C., Vath, J. E., Yu, W., and Martin, S. A. (1993).Anal. Chem. 65, 2791–2800. Hunt, D. F., Yates, J. R., III, Shabanowitz, J., Winston, S., and Hauer, C. R. (1986).Proc. Natl. Acad. Sci. USA 83, 6233–6237. Hunt, D. F., Henderson, R. A., Shabanowitz, J., Sakaguchi, K., Michel, H., Sevilir, N., Cox, A. L., Appella, E., and Engelhard, V. H. (1992).Science 255, 1261–1263. Karas, M., and Hillenkamp, F. (1988).Anal. Chem. 60, 2299–2301. Kaufmann, R., Spengler, B., and Lutzenkirchen, F. (1993).Rapid Commun. Mass Spectrom.7, 902–910. Lee, E. D., Muck, W., Henion, J. D., and Covey, T. R. (1988).J. Chromatog. 458, 313–321. Poulter, L., and Taylor, L. C. E. (1989).Int. J. Mass Spectrom. Ion Processes 91, 183–197. Anumula, K. R. (1993).Glycobiology 3, 511. Anumula, K. R. (1994).Anal. Biochem. (submitted). Hase, S. (1993).Meth. Mol. Biol. 14, 69–80. Kwon, H., and Kim, J. (1993).Anal. Biochem. 215, 243–252. Townsend, R. R. (1993).Am. Chem. Soc. Symp. 1993, 86–101. Creighton, T. E. (1977).J. Mol. Biol. 113, 275–293. Creighton, T. E. (1978).Prog. Biophys. Mol. Biol. 22, 221–298. Creighton, T. E. (1992).BioEssays 14, 195–199. Goldenberg, D. P. (1988).Biochemistry 27, 2481–2489. Goldenberg, D. P. (1992).Trends Biochem. Sci. 17, 257–261. Mendoza, J. A., Jarstfer, M. B. and Goldenberg, D. P. (1994).Biochemistry 33, 1143–1148. Weissman, J. S. and Kim, P. S. (1991).Science 253, 1386–1393. Weissman, J. S., and Kim, P. S. (1992).Proc. Natl. Acad. Sci. USA 89, 9900–9904. Zhang, J. X., and Goldenberg, D. P. (1993).Biochemistry 32, 14075–14081. Bargonetti, J.,et al. (1993).Genes Dev. 7, 12565. Fiscella, M.,et al. (1993).Oncogene 8, 1519. Lees-Miller, S.et al. (1992).Mol. Cell. Biol. 12, 5041. Levine, A. L. (1993).Annu. Rev. Biochem. 62, 623. Meek, D. (1994).Semin. Cancer Biol. (in press). Pavletich, N. P.,et al. (1993).Genes Dev. 7, 2556. Sakamoto, H.,et al. (1994).Proc. Natl. Acad. Sci. USA, (submitted). Ullrich, S. J.,et al. (1993).Proc. Natl. Acad. Sci. USA 90, 5954. Wang, Y.,et al. (1993).Genes Dev. 7, 2575. Anderson, C. W. (1994a).Trends Biochem. 18, 433. Anderson, C. W. (1994b).Semin. Cell Biol. (in press). Anderson, C. W.,et al. (1992).Crit. Rev. Eukaryotic Gene Express.2, 283. Bannister, A. J.,et al. (1993).Nucleic Acids Res. 21, 1289. Cai, Q.-Q.,et al. (1993).Cytogenet. Cell Genet. 65, 221. Dvir, A.,et al. (1992).Proc. Natl. Acad. Sci. USA 89, 11920. Falzon, M. (1993).J. Biol. Chem. 268, 10546. Gottlieb, T. M.,et al. (1993).Cell 72, 131. Lees-Miller, S. P.,et al. (1990).Mol. Cell. Biol. 10, 6472. Lees-Miller, S. P.,et al. (1992).Mol. Cell. Biol. 12, 5041. Alaupovic, P., Lee, D. M., and McConathy, W. J. (1972). Studies on the composition and structure of plasma lipoproteins. Distribution of lipoproteins. Distribution of lipoprotein families in major density classes of normal human plasma lipoproteins,Biochem. Biophys. Acta 260, 689–707. Kandoussi, A., Cachera, C., Parsy, D., Bard, J. M., and Fruchart, J. C. (1991). Quantitative determination of different apolipoprotein B containing lipoproteins by an enzyme linked immunosoabent assay: Apo B with apo c-III and apo B with apo E.J. Immunoassay 12, 305–323. Sandkamp, M., Tambyrajah, B. M., Assmann, G., and Schriewer, H. (1992). Determination of apolipoprotein B in apolipoprotein CII/CIII-containing lipoproteins by an immunoenzymetric assay,Eur. J. Clin. Chem. Clin. Biochem. 30, 223–228. Brandt, W. F., Alk, H., Chauhan, M., and Von Holt, C. (1984).FEBS Lett. 174, 228–232. Bhaskaran, R., Huang, C. C., Chang, D. K., and Yu, C. (1994a).J. Mol. Biol. 235, 1291–1301. Bhaskaran, R., Chang, D. K., and Yu, C. (1994b).J. Mol. Biol. (submitted). Dufton, M. J., and Hider, R. C. (1988).Pharmacol. Ther. 36, 1–40. Gilquin, B., Menez, A., and Toma, F. (1993).Biopolymers 33, 1659. Harvey, A. L. (1985).J. Toxicol. Toxin Rev. 4, 41–69. Lauterwein, J., and Wüthrick, K. (1978).FEBS Lett. 93, 181–184. Low, B. W., and Corfield, P. W. R. (1986).Eur. J. Biochem. 161, 579–287. Rees, B., Samama, J. P., and Moras, D. (1990).J. Mol. Biol. 214, 281–297. Yu, C., Bhaskaran, R., and Yang, C. C. (1993).Biochemistry 32, 2131–2136. Henschen, A. H. (1993).Tromb. Haemost. 70, 42–47. Henschen, A., and McDonagh, J. (1986). In Zwaal, R. F. A., and Hemker, H. C. (eds.),Blood Coagulation (Elsevier, Amsterdam), pp. 171–241. Krishna, R. G., and Wold, F. (1993).Adv. Enzymol. Related Areas of Mol. Biol. 67, 265–298. Chang, J. Y. (1989).J. Biol. Chem. 264, 3111–3115. Chang, J. Y.,et al. (1992).Biochemistry 31, 2874–2878. Kraft, R.,et al. (1988).Biol. Chem. Hoppe Seyler 369, 87–91. Mann, M., Højrup, D., and Roepstorff, D. (1993).Biol. Mass Spectr. 22, 338–345. Vorm, O., and Mann, M. (1994).J. Am. Soc. Mass Spectrom. (submitted). Vorm, O., Roepstorff, P., and Mann, M. (1994).Anal. Chem. (submitted). Green, P., Lipman, D., Hiller, L., Waterson, R., States, D., and Claverie, J.-M. (1993).Science 259, 1711–1716. Guevara, J., Jr., Spurlino, J., Jan, A. Y., Yang, C.-Y., Tulinsky, A., Prasad, B. V. V., Gaubatz, J. W., and Morrisett, J. D. (1993).Biophys. J. 64, 686–700. Koch, C. A., Anderson, D., Moran, M. F., Ellis, C., and Pawson, T. (1991).Science 252, 668–674. Knott, T. J., Pease, R. J., Powell, L. M., Wallis, S. C., Rall, S. C., Jr., Innerarity, T. L., Blackhart, B., Taylor, W. H., Marcel, Y., Milne, R., Johnson, D., Fuller, M., Lusis, A. J., McCarthy, B. J., Mahley, R. W., Levy-Wilson, B., and Scott, J. (1986).Nature 323, 734–738. Pawson, T. (1992).Curr. Opin. Struct. Biol. 2, 432–437. Smith, R. F., and Smith, T. F. (1992).Protein Eng. 5, 35–41. Trieu, V. N., and McConathy, W. J. (1990).Biochemistry 29, 5919–5924. Trieu, V. N., Zioncheck, T. F., Lawn, R. M., and McConathy, W. J. (1991).J. Biol. Chem. 266, 5480–5485. Wei, C.-F., Chen, S.-H., Yang, C.-Y., Marcel, Y.L., Milne, R. W., Li, W.-H., Sparrow, J. T., Gotto, A. M., Jr., and Chan, L. (1989).Proc. Natl. Acad. Sci. USA 82, 7265–7269. Yang, C.-Y., Lee, F.-S., Chan, L., Sparrow, D. A., Sparrow, J. T. and Gotto, A. M., Jr. (1986a).Biochem. J. 239, 777–780. Yang, C.-Y., Chen, S.-H., Gianturco, S. H., Bradley, W. A., Sparrow, J. T., Tanimura, M., Li, W.-H., Sparrow, D. A., DeLoof, H., Rosseneu, M., Lee, F.-S., Gu, Z.-W., Gotto, A.M., Jr., and Chan, L. (1986).Nature 323, 738–742. Yang, C.-Y., Chan, L., and Gotto, A. M., Jr. (1987). In Gotto, A. M., Jr. (ed.),Plasma Proteins (Elsevier, Amsterdam), pp. 77–93. Yang, C.-Y., Gu, Z.-W., Weng, S.-A., Kim, T. W., Chen, S. H., Pownall, H. J., Sharp, P. M., Liu, S.-W., Li, W.-H., Gotto, A. M., Jr., and Chan, L. (1989).Arteriosclerosis 9, 96–108. Ye, S. Q., Trieu, V. N., Stiers, D. L., and McConathy, W. J. (1988).J. Biol. Chem. 263, 6337–6343. Cesareni, G. (1992).FEBS Lett. 307, 66. Felici, F.,et al. (1991).J. Mol. Biol. 222, 301. Felici, F.,et al. (1993).Gene 128, 21–27. Greenwood, J.,et al. (1991).J. Mol. Biol. 220, 821. Marvin, D. A.,et al. (1994)J. Mol. Biol. 235, 260. Rowitch, D. H.,et al. (1988)J. Mol. Biol. 204, 663. Scott, J. K.,et al. (1992)Trends Biochem. Sci. 17, 241. Smith, G. P. (1993).Gene 128, 1. Veronese, F. Di Marzo,et al. (1994).J. Mol. Biol. (submitted). Willis, A. E.,et al. (1993).Gene 128, 79. Beg, Z. H., Stonik, J. A., Hoeg, J. M., Demosky, S. J., Jr., Fairwell, T., and Brewer, H. B., Jr. (1989). Human apolipoprotein A-I: Post-translational modification by covalent phosphorylation,J. Biol. Chem. 264, 6913–6921. Brunzell, J. D., Sniderman, A. D., Albers, J. J., and Kwiterovich, P. O., Jr. (1984). Apoprotein B and AI and coronary artery disease in humans,Arteriosclerosis 4, 79–83. Davis, R. A., Clinton, G. M., Borchardt, R. A., Malone-McNeal, M., Tan, T., and Lattier, G. R. (1984). Intrahepatic assembly of very low density lipopoproteins: Phosphorylation of small molecular weight apolipoprotein B,J. Biol. Chem. 259, 3383–3386. Ghisseli, G., Rohde, M. F., Tanenbaum, S., Krishnan, S., and Gotto, A. M. (1985). Origin of apolipoprotein A-I polymorphism in plasma,J. Biol. Chem. 260 15662–15668. Gordon, J. I., Sims, H. F., Lentz, S. R., Edelstein, C., Scanu, A. M., and Strauss, A. W. (1983). Proteolytic processing of human preproapolipoprotein A-I: A proposed defect in the conversion of proA-I to A-I in Tangier's disease,J. Biol. Chem. 258, 4037–4044. Grundy, S. M. (1966). Cholesterol and coronary heart disease.J. Am. Med. Assoc. 256, 2849–2858. Hoeg, J. M., Meng, M. S., Ronan, R., Fairwell, T., and Brewer, H. B., Jr. (1986). Human apolipoprotein A-l: Post- translational modification by fatty acid acylation,J. Biol. Chem. 261, 3911–3914. Olofsson, S.-O., Bijussel, G., Bostrom, K., Carlsson, P., Elovson, J., Protter, A. A., Reuben, M. A., and Bondgers, G. (1987). Apollipoprotein B: structure, biosynthesis and role in the lipoprotein assembly process,Atherosclerosis 68, 1–17. Swaminathan, N., and Aladjem, F. (1976). The monosaccharide composition and sequence of the carbohydrate moiety of human serum low density lipoproteins.Biochemistry 15, 1516–1522. Hartl, F.-U., Roman Hlodan, R., and Langer, T. (1994).Trends Biochem. Sci. 19(1), 20–25. Hendrick, J. P., and Hartl, F.-U. (1993).Annu. Rev. Biochem. 62, 349–384. Hendrix, R. W. (1979).J. Mol. Biol. 129, 375–392. Horowitz, P. M., and Su Hua (1994).J. Biol. Chem. (submitted). Lisin, N. M., and Hemmingsen, S. M. (1993).FEBS Lett. 324(1), 41–44. Paladini, A. A., Jr., and Weber, G. (1981).Biochemistry 20, 2587–2593.