LncRNA LOXL1-AS1 promotes proliferation and invasion and inhibits apoptosis in retinoblastoma by regulating the MAPK signaling pathway

Fabian ID, Onadim Z, Karaa E et al (2018) The management of retinoblastoma. Oncogene 37(12):1551–1560 Ancona-Lezama D, Dalvin LA, Shields CL (2020) Modern treatment of retinoblastoma: a 2020 review. Indian J Ophthalmol 68(11):2356–2365 Dimaras H, Corson TW (2019) Retinoblastoma, the visible CNS tumor: a review. J Neurosci Res 97(1):29–44 Selvarajah A, Flegg K, Sim W et al (2022) Clinical audit of retinoblastoma management: a retrospective single-institution study. Can J Ophthalmol 57(4):257–269 Gudiseva HV, Berry JL, Polski A et al (2019) Next-generation technologies and strategies for the management of retinoblastoma. Genes 10(12):1032 Taniue K, Akimitsu N (2021) The functions and unique features of LncRNAs in cancer development and tumorigenesis. Int J Mol Sci 22(2):632 Ouyang J, Zhong Y, Zhang Y et al (2022) Long non-coding RNAs are involved in alternative splicing and promote cancer progression. Br J Cancer 126(8):1113–1124 Yang M, Lu H, Liu J et al (2022) lncRNAfunc: a knowledgebase of lncRNA function in human cancer. Nucleic Acids Res 50(D1):D1295–D1306 Choudhari R, Sedano MJ, Harrison AL et al (2020) Long noncoding RNAs in cancer: from discovery to therapeutic targets. Adv Clin Chem 95:105–147 Rajagopal T, Talluri S, Akshaya RL et al (2020) HOTAIR LncRNA: a novel oncogenic propellant in human cancer. Clin Chim Acta 503:1–18 Gao YX, Gao HX, Xu XY et al (2020) Effects of lncRNA MALAT1 and lncRNA NKILA on proliferation, invasion and apoptosis of retinoblastoma. Eur Rev Med Pharmacol Sci 24(16):8296–8307 Zhang P, Zhao F, Jia K et al (2022) The LOXL1 antisense RNA 1 (LOXL1-AS1)/microRNA-423-5p (miR-423-5p)/ectodermal-neural cortex 1 (ENC1) axis promotes cervical cancer through the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway. Bioengineered 13(2):2567–2584 Yang X, Xing G, Liu S et al (2020) LncRNA LOXL1-AS1 promotes endometrial cancer progression by sponging miR-28-5p to upregulate RAP1B expression. Biomed Pharmacother 125:109839 Gao R, Zhang R, Zhang C et al (2018) LncRNA LOXL1-AS1 promotes the proliferation and metastasis of medulloblastoma by activating the PI3K/AKT pathway. Anal Cell Pathol 2018:9275685 Bai H, Li X, Wu S (2020) Up-regulation of long non-coding RNA LOXL1-AS1 functions as an oncogene in cervical squamous cell carcinoma by sponging miR-21. Arch Physiol Biochem 1–5 Jiang A, Wu W, Xu C et al (2022) SP2509, a selective inhibitor of LSD1, suppresses retinoblastoma growth by downregulating β-catenin signaling. Invest Ophthalmol Vis Sci 63(3):20 Francis JH, Roosipu N, Levin AM et al (2018) Current treatment of bilateral retinoblastoma: the impact of intraarterial and intravitreous chemotherapy. Neoplasia 20(8):757–763 Yang L, Zhang L, Lu L et al (2020) lncRNA UCA1 increases proliferation and multidrug resistance of retinoblastoma cells through downregulating miR-513a-5p. DNA Cell Biol 39(1):69–77 Yang M, Wei W (2019) Long non-coding RNAs in retinoblastoma. Pathol Res Pract 215(8):152435 Beermann J, Piccoli MT, Viereck J et al (2016) Non-coding RNAs in development and disease: background, mechanisms, and therapeutic approaches. Physiol Rev 96(4):1297–1325 Tian X, Xu G (2015) Clinical value of lncRNA MALAT1 as a prognostic marker in human cancer: systematic review and meta-analysis. BMJ Open 5(9):e8653 Zhang H, Zhong J, Bian Z et al (2017) Long non-coding RNA CCAT1 promotes human retinoblastoma SO-RB50 and Y79 cells through negative regulation of miR-218-5p. Biomed Pharmacother 87:683–691 Bi H, Wang G, Li Z et al (2020) Long Noncoding RNA (lncRNA) Maternally Expressed Gene 3 (MEG3) participates in chronic obstructive pulmonary disease through regulating human pulmonary microvascular endothelial cell apoptosis. Med Sci Monit 26:e920793 Hauser MA, Aboobakar IF, Liu Y et al (2015) Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. Hum Mol Genet 24(22):6552–6563 Chen S, Li W, Guo A (2019) LOXL1-AS1 predicts poor prognosis and promotes cell proliferation, migration, and invasion in osteosarcoma. Biosci Rep 39:BSR201904474 Wang D, Wang D, Wang N et al (2016) Long non-coding RNA BANCR promotes endometrial cancer cell proliferation and invasion by regulating MMP2 and MMP1 via ERK/MAPK signaling pathway. Cell Physiol Biochem 40(3–4):644–656 Li K, Tay FR, Yiu C (2020) The past, present and future perspectives of matrix metalloproteinase inhibitors. Pharmacol Ther 207:107465 Peng WX, Huang JG, Yang L et al (2017) Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer. Mol Cancer 16(1):161 Sun HY, Hu KZ, Yin ZS (2017) Inhibition of the p38-MAPK signaling pathway suppresses the apoptosis and expression of proinflammatory cytokines in human osteoarthritis chondrocytes. Cytokine 90:135–143 Zhuang R, Zhang X, Lu D et al (2019) lncRNA DRHC inhibits proliferation and invasion in hepatocellular carcinoma via c-Myb-regulated MEK/ERK signaling. Mol Carcinog 58(3):366–375