Lissencephaly with congenital muscular dystrophy and ocular abnormalities: cerebro-oculo-muscular syndrome

Springer Science and Business Media LLC - Tập 5 - Trang 35-37 - 1989
Makoto Sasaki1, Kunihiro Yoshioka1, Toru Yanagisawa1, Atsuko Nemoto2, Yuhei Takasago2, Takayuki Nagano3
1Department of Radiology, Iwate Medical College School of Medicine, Morioka, Japan
2Department of Pediatrics, Iwate Medical College School of Medicine, Morioka, Japan
3Department of Neurosurgery, Iwate Medical College School of Medicine, Morioka, Japan

Tóm tắt

A Japanese male infant with lissencephaly, congenital muscular dystrophy (CMD), and ocular abnormalities is described. This patient represents features of the cerebro-oculo-muscular syndrome. Cranial computerized tomography revealed diffuse agyria, low density of the white matter, and hypoplasia of the cerebellar vermis. Brain histology suggested type II lissencephaly. These findings are correlated with other similar conditions, such as Walker-Warburg syndrome, Fukuyama-type CMD, and muscle, eye and brain disease.

Tài liệu tham khảo

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