Liquid-Handling Robotic Workstations for Functional Genomics

SLAS Technology - Tập 9 - Trang 262-267 - 2004
Matthias G.O. Lorenz1
1National Cancer Institute, Advanced Technology Center, Gaithersburg, MD

Tóm tắt

More and more functional genomics laboratories are willing to invest in robotic workstations due to the higher throughput liquid-handling intensive nature of the work. In this report, the features of robotic workstations important for functional genomics are discussed. Workstations for functional genomics are useful for replication of clone sets, PCR and sequencing set-up and clean-up, hit picking, gel loading, and nucleic acid purification procedures. Workstations not only increase throughput, but also ensure that assay steps are performed consistently, human error- and learning curve-free from run to run. Workstations fit on a laboratory bench and may have several robotic arms in different configurations. Available configurations include grippers and single-, oligo-, or multi-probe heads, with uniform or independent spanning, and liquid-level detection or tracking options. Most hardware and software packages can be designed for integration with other automated devices, building towards a fully automated system.

Tài liệu tham khảo

10.1038/421665a

Alt D., 2003, OR Manager, 19, 30

10.1016/S1535-5535-04-00189-3

Hamilton S., 2002, Methods Mol. Biol., 190, 169

Rutherford M. L., 2001, Curr. Opin. Drug Discov. Devel., 4, 343

10.1162/106454601753238627

Felder R. A., 2001, CAP Today, 15, 42

10.1093/clinchem/46.5.740

10.1093/clinchem/46.5.784

10.1136/jcp.53.1.22

Narayanan S., 2000, MLO Med. Lab. Obs., 32, 24

10.1093/clinchem/46.5.757

10.1093/clinchem/46.5.764

10.1093/clinchem/46.5.746

10.1016/S1535-5535-04-00193-5

10.1016/S1535-5535-04-00204-7

10.3109/10425170009033232

10.2144/03342mt05

10.2144/00294st05

10.2144/03344rr04

10.2144/03343pf01

Otto P., 2002, J. Lab. Automation, 7, 75

Otto P., 2002, J. Lab. Automation, 7, 120

10.2144/02335bm08

10.1016/S1535-5535-04-00242-4

Harris N., 2002, J. Lab. Automation, 7, 75

Galbraith D. W., 2001, Methods Mol. Biol., 170, 131

10.1016/S1535-5535-04-00185-6

Thông tin
Thông tin xuất bản

SLAS Technology

Tập 9

262-267

Thông tin tác giả