Leisure Activities and Risk of Vascular Cognitive Impairment in Older Adults

Journal of Geriatric Psychiatry and Neurology - Tập 22 Số 2 - Trang 110-118 - 2009
Joe Verghese1, Cuiling Wang2, Mindy J. Katz3, Amy E. Sanders3, Richard B. Lipton4
1Department of Neurology Albert Einstein College of Medicine Bronx, New York 10461, USA
2Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, Einstein Aging Study, Albert Einstein College of Medicine, Bronx, New York
3Einstein Aging Study Albert Einstein College of Medicine, Bronx, New York, Department of Neurology, Albert Einstein College of Medicine, Bronx, New York
4Einstein Aging Study Albert Einstein College of Medicine, Bronx, New York, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, Department of Neurology, Albert Einstein College of Medicine, Bronx, New York

Tóm tắt

``Vascular cognitive impairment'' refers to cognitive impairment caused or associated with vascular risk factors, and encompasses a cognitive spectrum ranging from mild cognitive impairment to dementia. We examined the association of leisure activity participation to risk of developing VCI in the Bronx aging study. Over 21 years, 71 of the 401 participants who were free of dementia or VCI at entry developed VCI (49 participants with VCI without dementia). We derived Cognitive and Physical Activity Scales based on frequency of leisure activity participation. A 1-point increase on the Cognitive, but not Physical Activity Scale, was associated with lower risk of VCI (hazard ratio 0.931, 95% confidence interval [CI] 0.895-0.970) in Cox analysis. Participation in cognitive but not physical leisure activities is associated with lower risk of VCI with or without dementia. Prospective studies and clinical trials are needed to define the causal role of cognitive leisure activities in influencing vascular risk for cognitive decline.

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