Lead Exposure Inhibits Fracture Healing and Is Associated with Increased Chondrogenesis, Delay in Cartilage Mineralization, and a Decrease in Osteoprogenitor Frequency

Environmental Health Perspectives - Tập 113 Số 6 - Trang 749-755 - 2005
Jonathan J. Carmouche1, J. Edward Puzas2, Xinping Zhang2, Prarop Tiyapatanaputi2, Deborah A. Cory‐Slechta3, Robert Gelein3, Michael J. Zuscik2, Randy N. Rosier2, Brendan F. Boyce, Regis J. O’Keefe2, Edward M. Schwarz2
1Center for Musculoskeletal Research, University of Rochester Medical Center , University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA.
2Center for Musculoskeletal Research, University of Rochester Medical Center and
3Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA

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10.1359/jbmr.1999.14.11.1805

10.5271/sjweh.42

10.1002/jor.1100020115

Bonucci E, 1983, Osteoclast changes induced by lead poisoning (saturnism), Appl Pathol, 1, 241

10.1289/ehp.6555

CDC (Centers for Disease Control and Prevention), 2000, Blood lead levels in young children—United States and selected states, 1996–1999, MMWR Morbid Mortal Wkly Rep, 49, 1133

10.1359/jbmr.2001.16.2.338

10.1242/dev.00559

10.1016/S0892-0362(97)00047-0

Dowd TL, 1990, 31P NMR and saturation transfer studies of the effect of Pb2+ on cultured osteoblastic bone cells, J Biol Chem, 265, 20833, 10.1016/S0021-9258(17)45291-4

10.1038/382448a0

10.1097/00003086-199810001-00003

10.1007/s002239900214

10.1302/0301-620X.71B2.2925748

10.1016/S0925-4773(99)00142-2

10.1016/S0736-0266(03)00011-1

10.1084/jem.187.2.147

10.1101/gad.11.24.3482

10.1159/000047893

10.1006/enrs.1997.3760

Gruber HE, 1997, Osteopenia induced by long-term, low- and high-level exposure of the adult rat to lead, Miner Electrolyte Metab, 23, 65

10.1258/002367798780599866

10.1006/taap.1996.0209

10.1002/jor.1100110219

10.1080/00039899709602214

10.1210/endo.132.6.8504755

10.1002/art.11419

10.1016/0041-008X(90)90032-P

Markowitz ME, 1988, Sequential osteocalcin sampling as a biochemical marker of the success of treatment in moderately lead (Pb) poisoned children [Abstract], Pediatr Res, 23, 393

10.1007/BF00296069

10.1001/jama.281.24.2294

10.1016/0584-8547(93)80094-B

10.1148/radiology.136.1.6770416

10.1289/ehp.98106745

10.1289/ehp.919117

Puzas JE Campbell JR ’Keefe RJ Rosier RN2004. Nutrition and Bone Health. Totowa NJ:Humana Press .

Puzas JE, 1992, Osteoblasts and chondrocytes are important target cells for the toxic effects of lead, Neurotoxicology, 13, 783

10.1073/pnas.86.13.5133

10.1016/0167-4889(90)90249-D

Schwartz J, 1986, Relationship between childhood blood lead levels and stature, Pediatrics, 77, 281, 10.1542/peds.77.3.281

10.1101/gad.11.2.187

Shukla R, 1989, Effects of fetal and infant lead exposure on growth in stature, Pediatrics, 84, 604, 10.1542/peds.84.4.604

Silbergeld EK, 1993, Lead in bone: storage site, exposure source, and target organ, Neurotoxicology, 14, 225

10.1016/S0013-9351(88)80023-9

10.1080/00039896.1988.9935855

10.1172/JCI3523

10.1359/jbmr.2001.16.4.660

10.1172/JCI0215681

10.1016/S0736-0266(02)00007-4