Lactobacillus rhamnosus GG giảm thiểu rối loạn chức năng hàng rào và tín hiệu pro-inflammatory do interferon-γ và yếu tố hoại tử u-α gây ra
Tóm tắt
Biểu mô ruột tạo thành một hàng rào bảo vệ chống lại các thành phần bên trong lòng ruột và môi trường bên ngoài, được trung gian bởi các khớp chặt giữa các tế bào (TJs). Các khớp TJ có thể bị phá vỡ thông qua tín hiệu tế bào do các tác nhân gây bệnh đường ruột hoặc cytokine pro-inflammatory gây ra, góp phần vào nhiều rối loạn ruột khác nhau từ tiêu chảy nhiễm trùng cấp tính đến các bệnh viêm ruột mãn tính. Probiotics, như
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