Lab-on-a-chip: a component view
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Ahn CH et al (2004) Disposable smart lab on a chip for point-of-care clinical diagnostics. Proc IEEE 92(1):154–173
Andersson H, van der Wijngaart W, Nilsson P, Enoksson P, Stemme G (2001) A valve-less diffuser micropump for microfluidic analytical systems. Sens Actuators B 72(3):259–265
Applegate RW Jr et al (2006) Microfluidic sorting system based on optical waveguide integration and diode laser bar trapping. Lab Chip 6:422–426
Auroux PA, Iossifidis D, Reyes D, Manz A (2002) Micro total analysis systems. 2. Analytical standard operations and applications. Anal Chem 74(12):2637–2652
Bally M, Halter M, Vörös J, Grandin HM (2006) Optical microarray biosensing techniques. Surf Interface Anal 38(11):1442–1458
Banerjee A, Pais A, Papautsky I, Klotzkin D (2008) A polarization isolation method for high-sensitivity, low-cost on-chip fluorescence detection for microfluidic lab-on-a-chip. IEEE Sens J 8(5):621–627
Bhattacharyya A, Klapperich CM (2006) Thermoplastic microfluidic device for on-chip purification of nucleic acids for disposable diagnostics. Anal Chem 78:788–792
Blas M, Delaunay N, Rocca J-L (2008) Electrokinetic-based injection modes for separative microsystems. Electrophoresis 29(1):20–32
Bottausci F, Cardonne C, Meinhart C, Mezic I (2007) An ultrashort mixing length micromixer: the shear superposition micromixer. Lab Chip 7(3):396–398
Brown RB, Audet J (2008) Current techniques for single-cell lysis. J R Soc Interface 5(Suppl 2):131–138
Cady NC, Stelick S, Batt CA (2003) Nucleic acid purification using microfabricated silicon structures. Biosens Bioelectron 19(1):59–66
Cady NC, Stelick S, Kunnavakkam MV, Batt CA (2005) Real-time pcr detection of listeria monocytogenes using an integrated microfluidics platform. Sens Actuators B 107(1):332–341
Cai Z, Chen H, Chen B, Huang C (2006) A gravity driven micro flow injection wetting film extraction system on a polycarbonate chip. Talanta 68(3):895–901
Cao H, Tegenfeldt JO, Austin RH, Chou SY (2002) Gradient nanostructures for interfacing microfluidics and nanofluidics. Appl Phys Lett 81(16):3058
Carlen ET, van den Berg A (2007) Nanowire electrochemical sensors: can we live without labels? Lab Chip 7(1):19–23
Chandrasekaran A, Packirisamy M (2006) Absorption detection of enzymatic reaction using optical microfluidics based intermittent flow microreactor system. IEE Proc Nanobiotechnol 153(6):137–143
Chen Y-F, Yang JM, Gau J-J, Ho C-M, Tai Y-C (2000) Microfluidic system for biological agent detection. In: The 3rd international conference on the interaction of art and fluid mechanics, Zurich
Chen G, Lin Y, Wang J (2006) Monitoring environmental pollutants by microchip capillary electrophoresis with electrochemical detection. Talanta 68(3):497–503
Chen X, Cui D, Liu C, Li H, Chen J (2007) Continuous flow microfluidic device for cell separation, cell lysis and DNA purification. Anal Chim Acta 584(2):237–243
Cho BS et al (2003) Passively driven integrated microfluidic system for separation of motile sperm. Anal Chem 75(7):1671–1675
Choi S, Park J-K (2005) Microfluidic system for dielectrophoretic separation based on a trapezoidal electrode array. Lab Chip 5(10):1161–1167
Choi S, Song S, Choi C, Park J-K (2007) Continuous blood cell separation by hydrophoretic filtration. Lab Chip 7(11):1532–1538
Chooi J-W et al (2002) An integrated microfluidic biochemical detection system for protein analysis with magnetic bead-based sampling capabilities. Lab Chip 2:27–30
Craighead H (2006) Future lab-on-a-chip technologies for interrogating individual molecules. Nature 442(7101):387–393
Crevillen AG, Pumera M, Gonzalez MC, Escarpa A (2009) Towards lab-on-a-chip approaches in real analytical domains based on microfluidic chips/electrochemical multi-walled carbon nanotube platforms. Lab Chip 9(2):346–353
Crevillén AG, Hervás M, López MA, González MC, Escarpa A (2007) Real sample analysis on microfluidic devices. Talanta 74:342–357
Cross JD, Strychalski EA, Craighead HG (2007) Size-dependent DNA mobility in nanochannels. J Appl Phys 102(2):024701
Cygan ZT, Cabral JT, Beers KL, Amis EJ (2005) Microfluidic platform for the generation of organic-phase microreactors. Langmuir 21(8):3629–3634
Daniel D, Gutz IGR (2006) Electronic micropipettor: a versatile fluid propulsion and injection device for micro-flow analysis. Anal Chim Acta 571(2):218–227
De Vos KM, Bartolozzi I, Bienstman P, Baets R, Schacht E (2007) Optical biosensor based on silicon-on-insulator microring cavities for specific protein binding detection. In: Nanoscale imaging, spectroscopy, sensing, and actuation for biomedical applications IV (SPIE), pp 64470K–64478K
Doku GN, Verboom W, Reinhoudt DN, van den Berg A (2005) On-microchip multiphase chemistry—a review of microreactor design principles and reagent contacting modes. Tetrahedron 61(11):2733–2742
Dong H, Li CM, Zhou Q, Sun JB, Miao JM (2006) Sensitive electrochemical enzyme immunoassay microdevice based on architecture of dual ring electrodes with a sensing cavity chamber. Biosens Bioelectron 22(5):621–626
Easley CJ et al (2006) A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability. PNAS 103(51):19272–19277
Eijkel JCT, van den Berg A (2006) Nanotechnology for membranes, filters and sieves: a series of mini-reviews covering new trends in fundamental and applied research, and potential applications of miniaturised technologies. Lab Chip 6(1):19–23
Emrich CA, Tian H, Medintz IL, Mathies RA (2002) Microfabricated 384-lane capillary array electrophoresis bioanalyzer for ultrahigh-throughput genetic analysis. Anal Chem 74:5076–5083
Erickson D, Sinton D, Li D (2004) A miniaturized high-voltage integrated power supply for portable microfluidic applications. Lab Chip 4:87–90
Fan X, White IM, Zhu H, Suter JD, Oveys H (2007) Overview of novel integrated optical ring resonator bio/chemical sensors. Proc SPIE 6452M:6420–6451
Fissell WH et al (2009) High-performance silicon nanopore hemofiltration membranes. J Memb Sci 326(1):58–63
Fletcher PDI, Haswell SJ, Paunov VN (1999) Theoretical considerations of chemical reactions in micro-reactors operating under electroosmotic and electrophoretic control. Analyst 124:1273–1282
Foote RS, Khandurina J, Jacobson SC, Ramsey JM (2005) Preconcentration of proteins on microfluidic devices using porous silica membranes. Anal Chem 77(1):57–63
Fu AY, Chou HP, Spence C, Arnold FH, Quake SR (2002) An integrated microfabricated cell sorter. Anal Chem 74(11):2451–2457
Fu J, Schoch RB, Stevens AL, Tannenbaum SR, Han J (2007) A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and proteins. Nat Nano 2(2):121–128
Gao J, Xu J, Locascio LE, Lee CS (2001) Integrated microfluidic system enabling protein digestion, peptide separation, and protein identification. Anal Chem 73(11):2648–2655
Gao J, Yin XF, Fang ZL (2004) Integration of single cell injection, cell lysis, separation and detection of intracelullar constituents on a microfluidic chip. Lab Chip 4:47–52
Garstecki P, Fuerstman MJ, Fischbach MA, Sia SK, Whitesides GM (2006) Mixing with bubbles: a practical technology for use with portable microfluidic devices. Lab Chip 6(2):207–212
Ghafar-Zadeh E, Sawan M (2007a) A hybrid microfluidic/cmos capacitive sensor dedicated to lab-on-chip applications. IEEE Trans Biomed Circuits Syst 1(4):270–277
Ghafar-Zadeh E, Sawan M (2007b) A 0.18 μm cmos capacitive detection lab-on-chip. IEEE Custom Integrated Circuits Conference (CICC), pp 165–172
Ghafar-Zadeh E, Sawan M (2008) Charge-based capacitive sensor array for cmos-based laboratory-on-chip applications. IEEE Sens J 8(4):325–332
Ghafar-Zadeh E, Sawan M, Therriault D (2007) Novel direct-write cmos-based laboratory-on-chip: design, assembly and experimental results. Sens Actuators A 134(1):27–36
Ghosal S (2006) Electrokinetic flow and dispersion in capillary electrophoresis. Annu Rev Fluid Mech 38(1):309–338
Goerke O, Pfeifer P, Schubert K (2004) Water gas shift reaction and selective oxidation of co in microreactors. Appl Catal A Gen 263:11–18
Gong M, Wehmeyer KR, Stalcup AM, Limbach PA, Heineman WR (2007) Study of injection bias in a simple hydrodynamic injection in microchip CE. Electrophoresis 28(10):1564–1571
Grumann M, Geipel A, Riegger L, Zengerle R, Ducree J (2005) Batch-mode mixing on centrifugal microfluidic platforms. Lab Chip 5(5):560–565
Guo WP, Ma XM, Zeng Y (2005) Clinical laboratories on a chip for human immunodeficiency virus assay. In: Proceedings of the 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, pp 1274–1277
Haeberle S, Zengerle R (2007) Microfluidic platforms for lab-on-a-chip applications. Lab Chip 7(9):1094–1110
Hart SJ, Terray AV, Arnold J (2007) Particle separation and collection using an optical chromatographic filter. Appl Phys Lett 91(17):171121–171123
Herr AE et al (2007) Microfluidic immunoassays as rapid saliva-based clinical diagnostics. PNAS 104(13):5268–5273
Hong CC, Choi JW, Ahn CH (2004) A novel in-plane passive microfluidic mixer with modified tesla structures. Lab Chip 4(2):109–113
Huang C et al (2009) Localized surface plasmon resonance biosensor integrated with microfluidic chip. Biomed Microdevices 11(4):893–901
Hui WC et al (2007) Microfluidic systems for extracting nucleic acids for DNA and RNA analysis. Sens Actuators A 133(2):335–339
Ikuta K, Satake N, Ohashi T, Shibata M (2008) Finger-top total protein analysis system based on new biochemical ic chip.In: Micro Electro Mechanical Systems, 2008 MEMS 2008. IEEE 21st International Conference on, pp 236–239
Inglis DW, Riehn R, Austin RH, Sturm JC (2004) Continuous microfluidic immunomagnetic cell separation. Appl Phys Lett 85(21):5093–5095
Jain KK (2003) Nanodiagnostics: application of nanotechnology in molecular diagnostics. Expert Rev Mol Diagn 3:153–161
Jiang Z, Llandro J, Mitrelias T, Bland JAC (2006) An integrated microfluidic cell for detection, manipulation, and sorting of single micron-sized magnetic beads. 50th annual conference on magnetism and magnetic materials, (AIP), pp 08S103–105
Jin LJ, Ferrance J, Sanders JC, Landers JP (2003) A microchip-based proteolytic digestion system driven by electroosmotic pumping. Lab Chip 3(1):11–18
Jindal R, Cramer SM (2004) On-chip electrochromatography using sol-gel immobilized stationary phase with UV absorbance detection. J Chromatogr A 1044(1–2):277–285
Jung B, Fisher K, Ness KD, Rose KA, Raymond P, Mariella J (2008) Acoustic particle filter with adjustable effective pore size for automated sample preparation. Anal Chem 80:8447–8452
Kaigala GV et al (2008) An inexpensive and portable microchip-based platform for integrated RT-PCR and capillary electrophoresis. Analyst 133(3):331–338
Kataoka S, Endo A, Harada A, Ohmori T (2008) Fabrication of mesoporous silica thin films inside microreactors. Mater Lett 62(4–5):723–726
Klotzkin D, Papautsky I (2007) High-sensitivity integrated fluorescence analysis for microfluidic lab-on-a-chip. SPIE News
Kornaros G, Meidanis D, Papaeystathiou Y, Chantzandroulis S, Blionas S (2008) Architecture of a consumer lab-on-chip for pharmacogenomics. Consumer Electronics, 2008 (ICCE 2008). Digest of Technical Papers. International conference on consumer electronics, pp 1–2
Kua CH, Lam YC, Yang C, Youcef-Toumi K (2005) Review of bio-particle manipulation using dielectrophoresis. Singapore-MIT, pp 1–7
Kuswandi B, Nuriman, Huskens J, Verboom W (2007) Optical sensing systems for microfluidic devices: a review. Anal Chim Acta 601(2):141–155
Kutter JP, Jacobson SC, Ramsey JM (2000) Solid phase extraction on microfluidic devices. J Microcolumn Sep 12(2):93–97
Lau AY, Lee LP, Chan JW (2008) An integrated optofluidic platform for raman-activated cell sorting. Lab Chip 8(7):1116–1120
Lee SJ, Lee SY (2004) Micro total analysis system (μ-tas) in biotechnology. Appl Microbiol Biotechnol 64(3):289–299
Lee S-H, Cho SI, Lee C-S, Kim B-G, Kim Y-K (2005) Microfluidic chip for biochemical reaction and electrophoretic separation by quantitative volume control. Sens Actuators B 110(1):164–173
Lee M et al (2009a) Nanowire and nanotube transistors for lab-on-a-chip applications. Lab Chip 9(16):2267–2280
Lee Y-F, Lien K-Y, Lei H-Y, Lee G-B (2009b) An integrated microfluidic system for rapid diagnosis of dengue virus infection. Biosens Bioelectron 25(4):745–752
Li Y, Dalton C, Crabtree HJ, Nilsson G, Kaler KVIS (2007) Continuous dielectrophoretic cell separation microfluidic device. Lab Chip 7(2):239–248
Lien K-Y, Lin J-L, Liu C-Y, Lei H-Y, Lee G-B (2007) Purification and enrichment of virus samples utilizing magnetic beads on a microfluidic system. Lab Chip 7(7):868–875
Lien K-Y et al (2008) Microfluidic systems integrated with a sample pretreatment device for fast nucleic-acid amplification. J Microelectromech Syst 17(2):288–301
Lin Y, Timchalk CA, Matson DW, Wu H, Thrall KD (2001) Integrated microfluidics/electrochemical sensor system for monitoring of environmental exposures to lead and chlorophenols. Biomed Microdevices 3(4):331–338
Liu RH, Yang J, Lenigk R, Bonanno J, Grodzinski P (2004) Self-contained, fully integrated biochip for sample preparation, polymerase chain reaction amplification, and DNA microarray detection. Anal Chem 76(7):1824–1831
Liu RH et al (2006a) Fully integrated miniature device for automated gene expression DNA microarray processing. Anal Chem 78(6):1980–1986
Liu B-F, Xu B, Zhang G, Du W, Luo Q (2006b) Micro-separation toward systems biology. J Chromatogr A 1106(1–2):19–28
Liu D, Ou Z, Xu M, Wang L (2008) Simplified transient isotachophoresis/capillary gel electrophoresis method for highly sensitive analysis of polymerase chain reaction samples on a microchip with laser-induced fluorescence detection. J Chromatogr A 1214(1–2):165–170
Liu C-Y, Rick J, Chou T-C, Lee H-H, Lee G-B (2009) Integrated microfluidic system for electrochemical sensing of urinary proteins. Biomed Microdevices 11(1):201–211
Malic L, Kirk AG (2007) Integrated miniaturized optical detection platform for fluorescence and absorption spectroscopy. Sens Actuators A 135(2):515–524
Mao P, Han J (2009) Massively-parallel ultra-high-aspect-ratio nanochannels as mesoporous membranes. Lab Chip 9(4):586–591
Marcus JS, Anderson WF, Quake SR (2006) Microfluidic single-cell mrna isolation and analysis. Anal Chem 78(9):3084–3089
Mariella R (2008) Sample preparation: the weak link in microfluidics-based biodetection. Biomed Microdevices 10(6):777–784
Matsushita Y et al (2008) Photocatalytic reactions in microreactors. Chem Eng J 135(Suppl 1):S303–S308
McDonald JC, Whitesides GM (2002) Poly(dimethylsiloxane) as a material for fabricating microfluidic devices. Acc Chem Res 35(7):491–499
Melin J et al (2004) A liquid-triggered liquid microvalve for on-chip flow control. Sens Actuators B 100(3):463–468
Mello AJD, Beard N (2003) Dealing with ‘real’ samples: sample pre-treatment in microfluidic systems. Lab Chip 3(1):11N–20N
Minas G, Wolffenbuttel RF, Correia JH (2005) A lab-on-a-chip for spectrophotometric analysis of biological fluids. Lab Chip 5:1303–1309
Munce NR, Li J, Herman PR, Lilge L (2004) Microfabricated system for parallel single-cell capillary electrophoresis. Anal Chem 76(17):4983–4989
Nguyen N-T, Huang X (2001) Miniature valveless pumps based on printed circuit board technique. Sens Actuators A 88(2):104–111
Nilsson A, Petersson F, Jonsson H, Laurell T (2004) Acoustic control of suspended particles in micro fluidic chips. Lab Chip 4(2):131–135
Oh KW, Chinsung P, Kak N (2005) A world-to-chip microfluidic interconnection technology with dual functions of sample injection and sealing for a multichamber micro pcr chip. 18th IEEE international conference on micro electro mechanical systems, 2005 (MEMS 2005), pp 714–717
Ölvecká E, Masár M, Kaniansky D, Jöhnck M, Stanislawski B (2001) Isotachophoresis separations of enantiomers on a planar chip with coupled separation channels. Electrophoresis 22(15):3347–3353
Pamme N, Wilhelm C (2006) Continuous sorting of magnetic cells via on-chip free-flow magnetophoresis. Lab Chip 6(8):974–980
Pattekar AV, Kothare MV (2004) A microreactor for hydrogen production in micro fuel cell applications. J Microelectromech Syst 13(1):7–18
Perch-Nielsen IR, Rodrigo PJ, Alonzo CA, Glückstad J (2006) Autonomous and 3D real-time multi-beam manipulation in a microfluidic environment. Opt Express 14(25):12199–12205
Petersen NJ, Mogensen KB, Kutter JP (2002) Performance of an in-plane detection cell with integrated waveguides for UV/VIS absorbance measurements on microfluidic separation devices. Electrophoresis 23:3528–3536
Petersson F, Nilsson A, Holm C, Jonsson H, Laurell T (2005) Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces. Lab Chip 5(1):20–22
Piccin E, Laocharoensuk R, Burdick J, Carrilho E, Wang J (2007) Adaptive nanowires for switchable microchip devices. Anal Chem 79(12):4720–4723
Pipper J, Zhang Y, Neuzil P, Hsieh T-M (2008) Clockwork pcr including sample preparation. Angew Chem Int Ed 47(21):3900–3904
Popovtzer R, Neufeld T, Ron Ez, Rishpon J, Shacham-Diamand Y (2006) Electrochemical detection of biological reactions using a novel nano-bio-chip array. Sens Actuators B 119:664–672
Ramadan Q, Samper V, Poenar DP, Yu C (2006) An integrated microfluidic platform for magnetic microbeads separation and confinement. Biosens Bioelectron 21(9):1693–1702
Renzi RF et al (2004) Hand-held microanalytical instrument for chip-based electrophoretic separations of proteins. Anal Chem 77(2):435–441
Sabounchi P et al (2008) Sample concentration and impedance detection on a microfluidic polymer chip. Biomed Microdevices 10(5):661–670
Samel B, Nock V, Russom A, Griss P, Stemme G (2007) A disposable lab-on-a-chip platform with embedded fluid actuators for active nanoliter liquid handling. Biomed Microdevices 9(1):61–67
Schulte T, Bardell R, Weigl BH (2000) Sample acquisition and control on-chip microfluidic sample preparation. JALA 5(4):83–86
Schuster TG, Cho B, Keller LM, Takayama S, Smith GD (2003) Isolation of motile spermatozoa from semen samples using microfluidics. Reprod Biomed 7(1):75–81 Online
Seo S, Su T-W, Erlinger A, Ozcan A (2008) Multi-color lucas: lensfree on-chip cytometry using tunable monochromatic illumination and digital noise reduction. Cel Mol Bioeng 1:146–156
Shaikh KA et al (2005) A modular microfluidic architecture for integrated biochemical analysis. PNAS 102(28):9745–9750
Shih P-H et al (2008) On chip sorting of bacterial cells using sugar-encapsulated magnetic nanoparticles. J Appl Phys 103(7):07A316–313
Stanislas K (2003) Discussion on optical integration in lab-on-a-chip microsystems for medical diagnostics. Physica Status Solidi (C) 0(3):998–1012
Steigert J et al (2005) Integrated sample preparation, reaction, and detection on a high-frequency centrifugal microfluidic platform. JALA 10(5):331–341
Suzuki H, Yoneyama R (2003) Integrated microfluidic system with electrochemically actuated on-chip pumps and valves. Sens Actuators B 96(1–2):38–45
Suzuki H, Ho C-M, Kasagi N (2004) A chaotic mixer for magnetic bead-based micro cell sorter. J Microelectromech Syst 13(5):779–790
Suzuki Y, Yokoyama K, Namatame I (2006) Rapid and easy protein staining for SDS-page using an intramolecular charge transfer-based fluorescent reagent. Electrophoresis 27(17):3332–3337
Szita N et al (2005) Development of a multiplexed microbioreactor system for high-throughput bioprocessing. Lab Chip 5(8):819–826
Tai C-H, Hsiung S-K, Chen C-Y, Tsai M-L, Lee G-B (2007) Automatic microfluidic platform for cell separation and nucleus collection. Biomed Microdevices 9(4):533–543
Takagi J, Yamada M, Yasuda M, Seki M (2005) Continuous particle separation in a microchannel having asymmetrically arranged multiple branches. Lab Chip 5(7):778–784
Tsai C-H, Wang Y-N, Lin C-F, Yang R-J, Fu L-M (2006) Experimental and numerical investigation into leakage effect in injectors of microfluidic devices. Electrophoresis 27(24):4991–4998
Tseng H-Y, Wang C-H, Lin W-Y, Lee G-B (2007) Membrane-activated microfluidic rotary devices for pumping and mixing. Biomed Microdevices 9(4):545–554
Ukita Y et al (2008) Application of vertical microreactor stack with polystylene microbeads to immunoassay. Sens Actuators A 145–146:449–455
Vahey MD, Voldman J (2008) An equilibrium method for continuous-flow cell sorting using dielectrophoresis. Anal Chem
Vieillard J et al (2007) Application of microfluidic chip with integrated optics for electrophoretic separations of proteins. J Chromatogr B 845(2):218–225
Wang C-H, Lee G-B (2005) Automatic bio-sampling chips integrated with micro-pumps and micro-valves for disease detection. Biosens Bioelectron 21(3):419–425
Wang T-H, Chen Y-F, Masset S, Ho C-M, Tai Y-C (2000) Molecular beacon based micro biological detection system. In: Proceedings of international conference on mathematics and engineering techniques in medicine and biological sciences
Wang J, Escarpa A, Pumera M, Feldman J (2002) Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides. J Chromatogr A 952(1–2):249–254
Wang X, Saridara C, Mitra S (2005) Microfluidic supported liquid membrane extraction. Anal Chim Acta 543(1–2):92–98
Wang A-J, Xu J-J, Chen H-Y (2006) Proteins modification of poly(dimethylsiloxane) microfluidic channels for the enhanced microchip electrophoresis. J Chromatogr A 1107(1–2):257–264
Wang Y, Zhe J, Chung B, Dutta P (2008) A rapid magnetic particle driven micromixer. Microfluid Nanofluid 4(5):375–389
Waterval JCM, Lingeman H, Bult A, Underberg WJM (2000) Derivatization trends in capillary electrophoresis. Electrophoresis 21(18):4029–4045
Wei F et al (2008) Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe. Nucl Acids Res 36(11):e65
Weigl B, Bardell R, Kesler N, Morris C (2001) Lab-on-a-chip sample preparation using laminar fluid diffusion interfaces—computational fluid dynamics model results and fluidic verification experiments. Fresenius’ J Anal Chem 371(2):97–105
Wong SH, Ward MCL, Wharton CW (2004) Micro t-mixer as a rapid mixing micromixer. Sens Actuators B 100(3):359–379
Wu A, Wang L, Jensen E, Mathies R, Boser B (2010a) Modular integration of electronics and microfluidic systems using flexible printed circuit boards. Lab Chip 10(4):519–521
Wu H-W, Hsu R-C, Lin C-C, Hwang S-M, Lee G-B (2010b) An integrated microfluidic system for isolation, counting, and sorting of hematopoietic stem cells. Biomicrofluidics 4(2):024112
Xia HM, Wan SYM, Shu C, Chew YT (2005) Chaotic micromixers using two-layer crossing channels to exhibit fast mixing at low reynolds numbers. Lab Chip 5(7):748–755
Yang Z, Goto H, Matsumoto M, Maeda R (2000) Active micromixer for microfluidic systems using lead-zirconate-titanate(pzt)-generated ultrasonic vibration. Electrophoresis 21(1):116–119
Yang Z, Matsumoto S, Goto H, Matsumoto M, Maeda R (2001) Ultrasonic micromixer for microfluidic systems. Sens Actuators A 93(3):266–272
Yang Y, Li C, Kameoka J, Lee KH, Craighead HG (2005) A polymeric microchip with integrated tips and in situ polymerized monolith for electrospray mass spectrometry. Lab Chip 5(8):869–876
Yin D et al (2007) Planar optofluidic chip for single particle detection, manipulation, and analysis. Lab Chip 7(9):1171–1175
Yoo J-C, Moon M-C, Choi YJ, Kang CJ, Kim Y-S (2006) A high performance microfluidic system integrated with the micropump and microvalve on the same substrate. Microelectron Eng 83(4–9):1684–1687
Yu H, Kwon JW, Kim ES (2005) Chembio extraction on a chip by nanoliter droplet ejection. Lab Chip 5(3):344–349