L’apéline : une nouvelle adipokine impliquée dans le métabolisme énergétique

Tatemoto, 1998, Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor, Biochem Biophys Res Commun, 251, 471, 10.1006/bbrc.1998.9489 O’Dowd, 1993, A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11, Gene, 136, 355, 10.1016/0378-1119(93)90495-O De Mota, 2000, Cloning, pharmacological characterization and brain distribution of the rat apelin receptor, Neuroendocrinology, 72, 400, 10.1159/000054609 O’Carroll, 2000, Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues, Biochim Biophys Acta, 1492, 72, 10.1016/S0167-4781(00)00072-5 Carpéné, 2007, Expanding role for the apelin/APJ system in physiopathology, J Physiol Biochem, 63, 359, 10.1007/BF03165767 Llorens-Cortès, 2005, Apelin, a neuropeptide that counteracts vasopressin secretion, Med Sci, 21, 741 Japp, 2008, The apelin-APJ system in heart failure: pathophysiologic relevance and therapeutic potential, Biochem Pharmacol, 75, 1882, 10.1016/j.bcp.2007.12.015 Szokodi, 2002, Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility, Circ Res, 91, 434, 10.1161/01.RES.0000033522.37861.69 Boucher, 2005, Apelin, a newly identified adipokine up-regulated by insulin and obesity, Endocrinology, 146, 1764, 10.1210/en.2004-1427 Dray C, Debard C, Jager J, et al. Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans. Am J Physiol Endocrinol Metab;298:E1161–69. Sorhede-Winzell, 2005, The APJ receptor is expressed in pancreatic islets and its ligand, apelin, inhibits insulin secretion in mice, Regul Pept, 131, 12, 10.1016/j.regpep.2005.05.004 Guo, 2009, Apelin inhibits insulin secretion in pancreatic β-cells by activation of PI3-kinase-phosphodiesterase 3B, Endocrine Res, 34, 142, 10.3109/07435800903287079 Daviaud, 2006, TNFα up-regulates apelin expression in human and mouse adipose tissue, FASEB J, 20, 1530, 10.1096/fj.05-5243fje Heinonen, 2005, Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding, Regul Pept, 130, 7, 10.1016/j.regpep.2005.05.003 Li, 2006, Changes and relations of circulating visfatin, apelin, and resistin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects, Exp Clin Endocrinol Diabetes, 114, 544, 10.1055/s-2006-948309 Soriguer F, Garrido-Sanchez L, Garcia-Serrano S, et al. Apelin levels are increased in morbidly obese subjects with type 2 diabetes mellitus. Obes Surg 2009;19:1574–80. Erdem, 2008, Low plasma apelin levels in newly diagnosed type 2 diabetes mellitus, Exp Clin Endocrinol Diabetes, 116, 289, 10.1055/s-2007-1004564 Zhang, 2009, Low plasma apelin in newly diagnosed type 2 diabetes in Chinese people, Diabetes Care, 32, e150, 10.2337/dc09-1146 Castan-Laurell, 2008, Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ, Eur J Endocrinol, 158, 905, 10.1530/EJE-08-0039 Zhang, 2009, Association of apelin genetic variants with type 2 diabetes and related clinical features in Chinese Hans, Chin Med J, 122, 1273 Dray, 2008, Apelin stimulates glucose utilization in normal and obese insulin-resistant mice, Cell Metab, 8, 437, 10.1016/j.cmet.2008.10.003 Yue P, Jin H, Aillaud-Manzanera M, et al. Apelin is necessary for the maintenance of insulin sensitivity. Am J Physiol Endocrinol Metab 2009;298:E59–67. Tatemoto, 2001, The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism, Regul Pept, 99, 87, 10.1016/S0167-0115(01)00236-1 Duparc, 2009, Rôle de l’apéline cérébrale dans le maintien de l’homéostasie glucidique, Diabetes Metab, 35, A5, 10.1016/S1262-3636(09)71711-2 Lage, 2008, AMPK: a metabolic gauge regulating whole-body energy homeostasis, Trends Mol Med, 14, 539, 10.1016/j.molmed.2008.09.007 Gauthier, 2008, AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance, J Biol Chem, 283, 16514, 10.1074/jbc.M708177200 Higuchi, 2007, Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice, Endocrinology, 148, 2690, 10.1210/en.2006-1270 Frier, 2009, The effect of apelin treatment on skeletal muscle mitochondrial content, Am J Physiol, 297, R1761 Attané, 2009, Chronic apelin treatment effects on lipid metabolism in wild type and insulin-resistant mice, Diabetologia, 52, S20