Kangaroo mother care diminishes pain from heel lance in very preterm neonates: A crossover trial

Simons SH, van Dijk M, Anand KS, Roofthooft D, van Lingen RA, Tibboel D: Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates. Archives of Pediatrics & Adolescent Medicine 157(11):1058-64,. 2003

Stevens B, McGrath P, Gibbins S, Beyene J, Breau L, Camfield C, Finley A, Franck L, Howlett A, McKeever P, O'Brien K, Ohlsson A, Yamada J: Procedural pain in newborns at risk for neurologic impairment. Pain. 2003, 105: 27-35. 10.1016/S0304-3959(03)00136-2.

Johnston CC, Collinge JM, Henderson S, Anand KJS: A cross sectional survey of pain and analgesia in Canadian neonatal intensive care units. Clin J Pain. 1997, 13: 1-5. 10.1097/00002508-199712000-00008.

Stevens B, Johnston C, Taddio A, Jack A, Narciso J, Stremler R, Koren G, Aranda J: Management of pain from heel lance with lidocaine-prilocaine (EMLA) cream: is it safe and efficacious in preterm infants?. Journal of Developmental & Behavioral Pediatrics. 1999, 20: 216-221. 10.1097/00004703-199908000-00002.

Larsson BA, Norman M, Bjerring P, Egekvist H, Lagercrantz H, Olsson GL: Regional variations in skin perfusion and skin thickness may contribute to varying efficacy of topical, local anaesthetics in neonates. Paediatric Anaesthesia. 1996, 6: 107-110. 10.1111/j.1460-9592.1996.tb00370.x.

Stevens B, Yamada J, Ohlsson A: Sucrose for analgesia in newborn infants undergoing painful procedures [Systematic Review]. Cochrane Database of Systematic Reviews 2007;(1). 2007

Johnston CC, Filion F, Snider L, Limperopoulos C, Majnemer A, Pelausa E, Cake H, Stone S, Sherrard A, Boyer K: How much sucrose is too much sucrose?. Pediatrics. 2007, 119: 226-10.1542/peds.2006-3001.

Johnston CC, Filion F, Snider L, Majnemer A, Limperopoulos C, Walker CD, Veilleux A, Pelausa E, Cake H, Stone S, Sherrard A, Boyer K: Routine sucrose analgesia during the first week of life in neonates younger than 31 weeks' postconceptional age. Pediatrics. 2002, 110: 523-528. 10.1542/peds.110.3.523.

Lefrak L, Burch K, Caravantes R, Knoerlein K, DeNolf N, Duncan J, Hampton F, Johnston C, Lockey D, Martin-Walters C, McLendon D, Porter M, Richardson C, Robinson C, Toczylowski K: Sucrose analgesia: identifying potentially better practices. Pediatrics. 2006, 118: Suppl-202. 10.1542/peds.2006-0913R.

Anand KJ, Barton BA, McIntosh N, Lagercrantz H, Pelausa, Young TE, Vasa R: Analgesia and sedation in preterm neonates who require ventilatory support: results from the NOPAIN trial. Neonatal Outcome and Prolonged Analgesia in Neonates [published erratum appears in Arch Pediatr Adolesc Med 1999 Aug;153(8):895]. Archives of Pediatrics & Adolescent Medicine. 1999, 153: 331-338.

Carbajal R, Lenclen R, Jugie M, Paupe A, Barton BA, Anand KJ: Morphine does not provide adequate analgesia for acute procedural pain among preterm neonates. Pediatrics 115(6):1494-500,. 2005

Marsh DF, Hatch DJ, Fitzgerald M: Opioid systems and the newborn. [Review] [86 refs]. Br J Anaesth. 1997, 79: 787-795.

Cuzzolin L, Dal CM, Fanos V: NSAID-induced nephrotoxicity from the fetus to the child. [Review] [98 refs]. Drug Safety 24(1):9-18,. 2001

Akman I, Ozek E, Bilgen H, Ozdogan T, Cebeci D: Sweet solutions and pacifiers for pain relief in newborn infants. Journal of Pain 3(3):199-202,. 2002

Boyle EM, Freer Y, Khan-Orakzai Z, Watkinson M, Wright E, Ainsworth JR, McIntosh N: Sucrose and non-nutritive sucking for the relief of pain in screening for retinopathy of prematurity: a randomised controlled trial. Arch Dis Child: Fetal & Neonat. 2006, 91: F166-F168. 10.1136/adc.2005.087668.

Campos RG: Rocking and pacifiers: two comforting interventions for heelstick pain. Res Nurs Health. 1994, 17: 321-331. 10.1002/nur.4770170503.

Carbajal R: Crossover trial of analgesic efficacy of glucose and pacifier in very preterm neonates during subcutaneous injections. Pediatrics 110(2 Pt 1):389-93,. 2002, 110:

Stevens B, Johnston C, Franck L, Petryshen P, Jack A, Foster G: The efficacy of developmentally sensitive interventions and sucrose for relieving procedural pain in very low birth weight neonates. Nursing Research. 1999, 48: 35-43. 10.1097/00006199-199901000-00006.

Cignacco E, Hamers JPH, Stoffel L, van Lingen RA, Gessler P, McDougall J, Nelle M: The efficacy of non-pharmacological interventions in the management of procedural pain in preterm and term neonates. A systematic literature review. [References]. European Journal of Pain. 2007, 11: 139-152. 10.1016/j.ejpain.2006.02.010.

Corff KE, Seideman R, Venkataraman PS, Lutes L, Yates B: Facilitated tucking: a nonpharmacologic comfort measure for pain in preterm neonates. Journal of Obstetric, Gynecologic, & Neonatal Nursing. 1995, 24: 143-147. 10.1111/j.1552-6909.1995.tb02456.x.

Franck LS, Scurr K, Couture S: Parent views of infant pain and pain management in the neonatal intensive care unit. Newborn and Infant Nursing Reviews. 2001, 1: 106-113. 10.1053/nbin.2001.24429.

Franck LS, Allen A, Cox S, Winter I: Parents' views about infant pain in neonatal intensive care. Clin J Pain. 2005, 21: 133-139. 10.1097/00002508-200503000-00004.

Barr RG, Paterson J, McMartin L, Young S: Breastfeeding analgesia for procedural pain. Procedings of the Academic Pediatric Societies. 2001

Carbajal R: [Nonpharmacologic management of pain in neonates]. [Review] [44 refs] [French]. Archives de Pediatrie 12(1):110-6,. 2005

Gray L, Miller LW, Philipp BL, Blass EM: Breastfeeding is analgesic in healthy newborns. Pediatrics. 2002, 109: 590-593. 10.1542/peds.109.4.590.

Carbajal R, Veerapen S, Couderc S, Jugie M, Ville Y: Analgesic effect of breast feeding in term neonates: randomised controlled trial.[comment]. BMJ. 2003, 326: 13-10.1136/bmj.326.7379.13.

Efe E, Ozer ZC: The use of breast-feeding for pain relief during neonatal immunization injections. Appl Nurs Res. 2007, 20: 10-16. 10.1016/j.apnr.2005.10.005.

Gormally S, Barr RG, Wertheim L, Alkawaf R, Calinoiu N, Young SN: Contact and nutrient caregiving effects on newborn infant pain responses. Dev Med Child Neurol. 2001, 43: 28-38. 10.1017/S0012162201000056.

Blass EM, Miller LW: Effects of colostrum in newborn humans: dissociation between analgesic and cardiac effects. Journal of Developmental & Behavioral Pediatrics. 2001, 22: 385-390.

Blass EM: Milk induced hypoalgesia in human newborns. Pediatrics. 1997, 99: 825-829. 10.1542/peds.99.6.825.

Bilgen H, Ozek E, Cebeci D, Ors R: Comparison of sucrose, expressed breast milk, and breast-feeding on the neonatal response to heel prick. Journal of Pain 2(5):301-5,. 2001

Ors R, Ozek E, Baysoy G, Cebeci D, Bilgen H, Turkuner M, Basaran M: Comparison of sucrose and human milk on pain response in newborns. European Journal of Pediatrics. 1999, 158: 63-66. 10.1007/s004310051011.

Gray L, Watt L, Blass EM: Skin-to-skin contact is analgesic in healthy newborns. Pediatrics. 2000, 105: e14-10.1542/peds.105.1.e14.

Johnston CC, Stevens B, Pinelli J, Gibbins S, Filion F, Jack A, Steele S, Boyer K, Veilleux A: Kangaroo care is effective in diminishing pain response in preterm neonates. Archives of Pediatrics & Adolescent Medicine 157(11):1084-8,. 2003

SM LH, Hosseini R, DL T: Skin-to-skin contact (Kangaroo Care) analgesia for preterm infant heelstick. AACN Clinical Issues. 2005, 16: 373-387.

Moore ER, Anderson GC, Bergman N: Early skin-to-skin contact for mothers and their healthy newborn infants [Systematic Review]. Cochrane Database of Systematic Reviews. 2007

Fitzgerald M, Beggs S: The neurobiology of pain: developmental aspects. [Review] [120 refs]. Neuroscientist. 2001, 7: 246-257.

Fitzgerald M, Shaw A, MacIntosh N: The postnatal development of the cutaneous flexor reflex : a comparative study in premature infants and newborn rat pups. Dev Med Child Neurol. 1988, 30: 520-526.

Barr RG, Young SN: A two phase model of soothing taste response: Implications for a taste probe of temperament and emotion regulation. Soothing and Stress. Edited by: Lewis M and Ramsay DS. 1999, Hillsdale, NJ, Lawerance Earlbaum Associates, 109-137.

Blass EM, Ciaramitaro V: A new look at some old mechanisms in human newborns: Taste and tactile determinants of state, affect, and action. Monographs of the Society for Research in Child Development. 1994, 59: 1-80. 10.2307/1166096.

Nikfar S, Abdollahi M, Etemad F, Sharifzadeh M: Effects of sweetening agents on morphine-induced analgesia in mice by formalin test. General Pharmacology. 1997, 29: 583-586. 10.1016/S0306-3623(96)00575-7.

Segato FN, Castro-Souza C, Segato EN, Morato S, Coimbra NC: Sucrose ingestion causes opioid analgesia. Brazilian Journal of Medical & Biological Research. 1997, 30: 981-984.

Taddio A, Shah V, Shah P, Katz J: Beta-endorphin concentration after administration of sucrose in preterm infants. Archives of Pediatrics & Adolescent Medicine 157(11):1071-4,. 2003

Eriksson M, Gradin M, Schollin J: Oral glucose and venepuncture reduce blood sampling pain in newborns. Early Hum Dev. 1999, 55: 211-218. 10.1016/S0378-3782(99)00018-3.

Dupont WD: Power calculations for matched case-control studies. Biometrics. 1988, 44: 1157-1168. 10.2307/2531743.

Baird TM, Paton JB, Fisher DE: Improved oxygenation with prone positioning in neonates: stability of increased transcutaneous PO2. J Perinatol. 1991, 11: 315-318.

Martin RJ, DiFiore JM, Korenke CB, Randal H, Miller MJ, Brooks LJ: Vulnerability of respiratory control in healthy preterm infants placed supine. J Pediatr. 1995, 127: 609-614. 10.1016/S0022-3476(95)70125-7.

Stevens BJ, Johnston C, Petryshen P, Taddio A: Premature infant pain profile: development and initial validation. Clin J Pain. 1996, 12: 13-22. 10.1097/00002508-199603000-00004.

Stevens BJ, Johnston CC, Franck LS, Petryshen P, Jack A: Validation of the Premature Infant Pain Profile (PIPP) with very low birthweight neonates. International Pediatric Nursing Research Symposium on Clinical Care of the Child and Family. 1999, 8:

Ballantyne M, Stevens B, McAllister M, Dionne K, Jack A: Validation of the premature infant pain profile in the clinical setting. Clin J Pain. 1999, 15: 297-303. 10.1097/00002508-199912000-00006.

McNair C, Ballantyne M, Dionne K, Stephens D, Stevens B: Postoperative pain assessment in the neonatal intensive care unit. Arch Dis Child: Fetal & Neonat. 2004, 89: F537-F541. 10.1136/adc.2003.032961.

Grunau R: Neonatal responses to invasive procedures. Nurs Times. 1991, 87: 53-54.

Grunau RE, Oberlander TF, Holsti L, Whitfied MF: Bedside application of the Neonatal Facial Coding System in pain assessment of premature neonates. Pain. 1998, 76: 277-286. 10.1016/S0304-3959(98)00046-3.

Grunau RVE, Craig KD: Facial activity as a measure of neonatal pain expression. Advances in Pain Therapy and Research, Vol 15: Pediatric Pain. Edited by: Tyler DC and Krane EJ. 1990, New York, Raven Press, 147-156.

Grunau RVE, Johnston CC, Craig KD: Neonatal facial and cry responses to invasive and noninvasive procedures. Pain. 1990, 42: 295-305. 10.1016/0304-3959(90)91142-6.

Prechtl HFR: The behavioral states of the newborn infant: a review. Brain Res. 1974, 76: 185-212. 10.1016/0006-8993(74)90454-5.

Prechtl HFR, Beintema D: The neurological examination of the fullterm newborn infant. Clin Dev Med. 1977, 63:

Richardson DK, Corcoran JD, Escobar GJ, Lee SK: SNAP-II and SNAPPE-II: Simplified newborn illness severity and mortality risk scores. J Pediatr. 2001, 138: 92-100. 10.1067/mpd.2001.109608.

Grunau RVE, Craig KD: Pain expression in neonates : Facial action and cry. Pain. 1987, 28: 395-410. 10.1016/0304-3959(87)90073-X.

Als H: The preterm infant: A model for the study of fetal brain expectation. Lecanuet, Jean-Pierre (Ed); Fifer, William P. 1951, A-471.

Als H: Towards a synactive theory of development: promise for the assessment of infant individuality. Infan Mental Health J. 1982, 3: 229-243. 10.1002/1097-0355(198224)3:4<229::AID-IMHJ2280030405>3.0.CO;2-H.

Charpak N, Ruiz JG, Zupan J, Cattaneo A, Figueroa Z, Tessier R, Cristo M, Anderson G, Ludington S, Mendoza S, Mokhachane M, Worku B: Kangaroo Mother Care: 25 years after. [Review] [60 refs]. Acta Paediatrica. 2005, 94: 514-522. 10.1080/08035250510027381.

ER M, GC A: Randomized controlled trial of very early mother-infant skin-to-skin contact and breastfeeding status. Journal of midwifery & women's health. 2007, 116-125.

Acolet D, Sleath K, Whitelaw A: Oxygenation, heart rate, and temperature in very low birthweight infants during skintosin contact with their mothers. Acta Paediatr Scand. 1989, 78: 189-193. 10.1111/j.1651-2227.1989.tb11055.x.

Bier JAB, Ferguson A, Liebling JA, Morales Y, Archer D, Oh W, Bohr B: Skintoskin contact improves physiologic stress of breastfed low birthweight infants. Pediatr Res. 1995, 37: 103A-

Chwo MJ, Anderson GC, Good M, Dowling DA, Shiau SH, Chu DM: A randomized controlled trial of early kangaroo care for preterm infants: effects on temperature, weight, behavior, and acuity. Journal of Nursing Research: JNR. 2002, 10: 129-142.

deLeeuw R, Colin EM, Dunnebier EA, Mirmiran M: Physiologic effects of kangaroo care in very small preterm infants. Biol Neonate. 1991, 59: 149-155.

Feldman R, Eidelman AI: Skin-to-skin contact (Kangaroo Care) accelerates autonomic and neurobehavioural maturation in preterm infants. Developmental Medicine & Child Neurology. 2003, 45: 274-281. 10.1017/S0012162203000525.

Ludington-Hoe SM, Nguyen N, Swinth JY, Satyshur RD: Kangaroo care compared to incubators in maintaining body warmth in preterm infants. Biological Research for Nursing. 2000, 2: 60-73. 10.1177/109980040000200107.

Sloan NL, Camacho LW, Rojas EP, Stern C: Kangaroo mother method: randomised controlled trial of an alternative method of care for stabilised low-birthweight infants. Maternidad Isidro Ayora Study Team. Lancet. 1994, 344: 782-785. 10.1016/S0140-6736(94)92341-8.

Bauer K, Pyper A, Sperling P, Uhrig C, Versmold H: Effects of gestational and postnatal age on body temperature, oxygen consumption, and activity during early skin-to-skin contact between preterm infants of 25-30-week gestation and their mothers. Pediatr Res. 1998, 44: 247-251. 10.1203/00006450-199808000-00018.