KCNS1, but Not GCH1, Is Associated With Pain Intensity in a Black Southern African Population With HIV-Associated Sensory Neuropathy

Journal of acquired immune deficiency syndromes (1999) - Tập 63 Số 1 - Trang 27-30 - 2013
Liesl M. Hendry1,2, Zané Lombard3, Antonia Wadley4, Peter Kamerman4
1Division of Human Genetics, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
2National Health Laboratory Service, Johannesburg, South Africa
3Wits Bioinformatics, University of the Witwatersrand, Johannesburg, South Africa
4Brain Function Research Group, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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Tài liệu tham khảo

Kamerman, 2012, HIV-associated sensory neuropathy: risk factors and genetics., Curr Pain Headache Rep, 16, 226, 10.1007/s11916-012-0257-z

Phillips, 2010, . Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials., PLoS One, 5, e14433, 10.1371/journal.pone.0014433

Clifford, 2012, . A randomized, double-blind, controlled study of NGX-4010, a capsaicin 8 dermal patch, for the treatment of painful HIV-associated distal sensory polyneuropathy., J Acquir Immune Defic Syndr, 59, 126, 10.1097/QAI.0b013e31823e31f7

Wadley, 2011, . HIV neuropathy risk factors and symptom characterization in stavudine-exposed South Africans., J Pain Symptom Manage, 41, 700, 10.1016/j.jpainsymman.2010.07.006

Kim, 2004, . Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament., Pain, 109, 488, 10.1016/j.pain.2004.02.027

Young, 2012, Genetic basis of pain variability: recent advances., J Med Genet, 49, 1, 10.1136/jmedgenet-2011-100386

Costigan, 2010, . Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1., Brain, 133, 2519, 10.1093/brain/awq195

Thony, 2000, Tetrahydrobiopterin biosynthesis, regeneration and functions., Biochem J, 347, 1, 10.1042/bj3470001

Tegeder, 2006, . GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence., Nat Med, 12, 1269, 10.1038/nm1490

Lotsch, 2007, . Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms., Clin Chem, 53, 1010, 10.1373/clinchem.2006.082883

Kim, 2007, Lack of influence of GTP cyclohydrolase gene (GCH1) variations on pain sensitivity in humans., Mol Pain, 3, 6, 10.1186/1744-8069-3-6

Wadley, 2012, . Analysis of a previously identified pain-protective haplotype and individual polymorphisms in the GCH1 gene in Africans with HIV-associated sensory neuropathy: a genetic association study., J Acquir Immune Defic Syndr, 60, 20, 10.1097/QAI.0b013e31824bcc17

Tishkoff, 2009, . The genetic structure and history of Africans and African Americans., Science, 324, 1035, 10.1126/science.1172257

Cherry, 2005, . Evaluation of a clinical screening tool for HIV-associated sensory neuropathies., Neurology, 65, 1778, 10.1212/01.wnl.0000187119.33075.41

2003, Nature., , 426, 789

Flicek, 2012, . Ensembl 2012., Nucleic Acids Res, 40, D84, 10.1093/nar/gkr991

Kinsella, 2011, . Ensembl BioMarts: a hub for data retrieval across taxonomic space., Database (Oxford), 2011, bar030, 10.1093/database/bar030

Lin, 2009, . Medium- to high-throughput SNP genotyping using VeraCode microbeads., Methods Mol Biol, 496, 129, 10.1007/978-1-59745-553-4_10

Purcell, 2007, . PLINK: a tool set for whole-genome association and population-based linkage analyses., Am J Hum Genet, 81, 559, 10.1086/519795