Ivermectin excreted in cattle dung after subcutaneous injection or pour-on treatment: concentrations and impact on dung fauna

Bulletin of Entomological Research - Tập 82 Số 2 - Trang 257-264 - 1992
Christian Sommer1, Bente Steffansen2, Bjarne Nielsen3, J. Grønvold4, Kathleen M. Jensen5, Jørgen B. Jespersen5, J. Springborg2, P. Nansen4
1Institute of Population Biology, University of Copenhagen, DK
2Chemistry Department, Royal Veterinary and Agricultural University, Frederiksberg C, DK
3Institute of Biology, University of Århus, C, DK
4Department of Veterinary Microbiology, Laboratory of Parasitology, Royal Veterinary and Agricultural University, Frederiksberg C, DK
5Danish Pest Infestation Laboratory, Lyngby, DK

Tóm tắt

AbstractHeifers were treated with the recommended doses of ivermectin: 0.2 mg/ kg bw by subcutaneous injection or 0.5 mg/kg bw by pour-on. An analytic procedure is described and used for the detection of ivermectin residues excreted in dung. A large amount of the higher pour-on dose was excreted during the first five days after dosing due to a more rapid distribution to intestinal contents. Later faecal concentrations after the pour-on treatment were lower than those found after subcutaneous injection. No degradation of ivermectin was detected in pats exposed in the field for up to 45 days. Ivermectin excreted in dung voided 1–2 days after both treatments significantly reduced the number of dung inhabiting larvae ofAphodiusspp. (Coleoptera: Scarabaeidae), but no effect was seen in dung deposited 13–14 days after treatments. Development of cyclorrhaphan larvae was inhibited in dung deposited up to 28–29 days after subcutaneous injection treatment, but only inhibited in dung deposited up to 13–14 days after pour-on treatment. The numbers of Nematocera larvae were not affected. In a laboratory bioassay the DipteraMusca autumnalisDeGeer andHaematobia irritans(Linnaeus) suffered higher mortality in dung from heifers treated by the subcutaneous injection 13–14 days earlier than in dung from heifers treated by pour-on at the same time. After subcutaneous injection, a significant reduction in the rate of decomposition was found in dung from heifers treated 1–2 days earlier, whereas pour-on led to a delayed decomposition in dung collected up to 13–14 days after treatment.

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Thông tin xuất bản

Bulletin of Entomological Research

Tập 82 Số 2

257-264

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