Jürgen Lademann1, Nina Otberg1, Heike Richter1, H.‐J. Weigmann1, U. Lindemann1, Hans Schaefer1, Wolfram Sterry1
1Center of Experimental and Applied Cutaneous Physiology, Dermatological Clinic, Medical Faculty Charité, Humboldt University, Berlin, Germany
Tóm tắt
The influence of specific follicle properties, sebum production and hair growth on the follicular penetration of topically applied substances was investigated. The behavior of follicles identified in selected skin areas of volunteers was analyzed by various tape stripping and staining methods in combination with laser scanning microscopy. Furthermore hair growth in the selected skin areas was determined. A correlation between sebum production, hair growth activity and follicular penetration was observed.