Inverse Opal Photonic Gel Containing Charge Stabilized Boronate Anions for Glucose Sensing at Physiological pH

Physica Status Solidi - Rapid Research Letters - Tập 13 Số 2 - 2019
Dongyoun Kim1,2, Young Gook Koh2, Wonmok Lee1,2
1Department of Chemistry, Sejong University, 98 Gunja-dong, Gwangjin-gu, Seoul 05006, Korea
2Engain Co. Ltd., Korea Bio Park, Bldg. C-201, Seongnam, Gyeonggi-do 13488, Korea

Tóm tắt

A glucose‐sensing inverse opal photonic gel (IOPG) that functions at physiological pH has been demonstrated in this study. Photopolymerization of the monomer mixtures is templated by opal films. The structural colors of the optimized IOPG change from red to green upon the addition of the glucose solution at pH 7.4 due to the formation of 2:1 boronates–glucose complexes which induces a shrinkage of IOPG. The intramolecular charge stabilization of anionic boronate by neighboring quaternary‐amine group leads to an efficient diester formation at physiological pH. The optimized IOPG glucose sensor shows a response time as fast as 1 min, as well as reversible and reproducible sensing responses to make it a promising candidate for continuous glucose monitoring system.

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Physica Status Solidi - Rapid Research Letters

Tập 13 Số 2

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