Intracellular Membrane Transport Systems in Trypanosoma brucei

Traffic - Tập 5 Số 12 - Trang 905-913 - 2004
Mark C. Field1, Mark Carrington2
1Department of Biological Sciences, Imperial College, London, UK
2Department of Biochemistry, Tennis Court Road, University of Cambridge, Cambridge, UK

Tóm tắt

Trypanosomes belong to the order kinetoplastida, an early diverging group of organisms in the eukaryotic lineage. The principal reasons for interest in these organisms are twofold; they provide a superb distant triangulation point from which to assess global features of eukaryotic biology and, more importantly, they are representative of a number of pathogenic parasitic protozoa with a huge public health impact –Trypanosoma brucei, T. cruzi and Leishmania spp. Recent advances in the study of intracellular transport in T. brucei have been considerable, and a fuller picture of the complexity, function and role that the endomembrane system plays in trypanosomes is finally emerging.

Từ khóa


Tài liệu tham khảo

10.1016/S0065-308X(01)49037-3

10.1016/S0966-842X(01)02073-X

10.1016/S0166-6851(01)00417-0

10.1046/j.1365-2958.2003.03245.x

10.1042/bj2940305

10.1016/S0966-842X(02)02309-0

Barry JD., 1979, Capping of variable antigen on Trypanosoma brucei, and its immunological and biological significance, J Cell Sci, 37, 287, 10.1242/jcs.37.1.287

10.1016/S1471-4922(02)02391-7

Djikeng A, 2004, Analysis of gene function in Trypanosoma brucei using RNA interference, Methods Mol Biol, 265, 73

10.1006/expr.1995.1122

10.1016/j.molbiopara.2003.12.014

Ackers JP, 2004, A bioinformatic analysis of the RAB genes of Trypanosoma†brucei, Mol Biochem Parasitol

10.1016/S0166-6851(02)00023-3

10.1046/j.1600-0854.2003.00141.x

10.1016/S0378-1119(03)00381-0

Jeffries TR, 2001, A developmentally regulated rab11 homologue in Trypanosoma brucei is involved in recycling processes, J Cell Sci, 114, 2617, 10.1242/jcs.114.14.2617

Field H, 1999, TbRab2p, a marker for the endoplasmic reticulum of Trypanosoma brucei, localises to the ERGIC in mammalian cells, J Cell Sci, 112, 147, 10.1242/jcs.112.2.147

10.1074/jbc.273.48.32102

10.1074/jbc.M407271200

10.1042/BJ20030469

10.1016/S0166-6851(02)00133-0

10.1074/jbc.M110055200

10.1016/j.molbiopara.2004.06.007

10.1074/jbc.272.16.10498

10.1091/mbc.12.10.2907

10.1074/jbc.M312178200

10.1016/S0166-6851(03)00212-3

10.1083/jcb.103.1.255

Morgan GW, 2001, Developmental and morphological regulation of clathrin‐mediated endocytosis in Trypanosoma brucei, J Cell Sci, 114, 2605, 10.1242/jcs.114.14.2605

10.1034/j.1600-0854.2002.30805.x

10.1016/S0166-6851(03)00055-0

10.1242/jcs.115.4.805

10.1042/bj3350681

10.1093/emboj/19.1.10

10.1016/S0014-5793(01)02172-X

10.1016/S0092-8674(01)00215-X

10.1083/jcb.200212101

10.1091/mbc.10.4.1043

10.1016/S0166-6851(99)00192-9

He CY, 2004, Golgi duplication in Trypanosoma brucei, J Cell Biol, 163, 313

10.1007/BF00932695

10.1016/S0166-6851(97)00191-6

10.1242/jcs.00938

10.1091/mbc.E02-10-0640

10.1093/emboj/cdg481

10.1038/sj.emboj.7600094

10.1016/j.molbiopara.2004.07.007

Ziegelbauer K, 1992, Molecular characterization of two invariant surface glycoproteins specific for the blood‐ stream stage of Trypanosoma brucei, J Biol Chem, 267, 10797, 10.1016/S0021-9258(19)50089-8

10.1038/362603a0

10.1093/glycob/cwf079

10.1016/S0166-6851(01)00268-7

Chung WL, 2004, Cytoplasmic targeting signals in transmembrane invariant surface glycoproteins of trypanosomes, J Biol Chem

Thông tin
Thông tin xuất bản

Traffic

Tập 5 Số 12

905-913

Thông tin tác giả