Interactions between Zinc Deficiency and Environmental Enteropathy in Developing Countries

Desai, 1969, 'Flat' jejunal mucosa in the tropics, Indian J Med Sci, 23, 1 Schenk, 1968, Morphology of small bowel biopsies, Am J Clin Nutr, 21, 944, 10.1093/ajcn/21.9.944 Walker-Smith, 1999 McKay, 2010, Environmental enteropathy: new targets for nutritional interventions, Int Health, 2, 172, 10.1016/j.inhe.2010.07.006 Humphrey, 2009, Child undernutrition, tropical enteropathy, toilets and handwashing, Lancet, 374, 1032, 10.1016/S0140-6736(09)60950-8 Prendergast, 2012, Review: enteropathies in the developing world: neglected effects on global health, Am J Trop Med Hyg, 86, 756, 10.4269/ajtmh.2012.11-0743 Prasad, 1991, Discovery of human zinc deficiency and studies in experimental model, Am J Clin Nutr, 53, 403, 10.1093/ajcn/53.2.403 Brown, 2004, International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control, Food Nutr Bull, 25, S99 Moynahan, 1974, Acrodermatitis Enteropathica: a lethal inherited human zinc-deficiency disorder [letter], Lancet, 2, 399, 10.1016/S0140-6736(74)91772-3 Black, 2013, Maternal and child undernutrition and overweight in low-income and middle-income countries, Lancet, 382, 427, 10.1016/S0140-6736(13)60937-X de Benoist, 2007, Conclusions of the joint WHO/UNICEF/IAEA/IZiNCG interagency meeting of zinc status indicators, Food Nutr Bull, 28, S480, 10.1177/15648265070283S306 Wessells, 2012, Estimating the global prevalence of zinc deficiency: results based on zinc availability in national food supplies and the prevalence of stunting, PLoS ONE, 7, e50568, 10.1371/journal.pone.0050568 Krebs, 2000, Overview of zinc absorption and excretion in the human gastrointestinal tract, J Nutr, 130, S1374, 10.1093/jn/130.5.1374S Fukada, 2011, Zinc homeostasis and signaling in health and disease: zinc signaling, J Biol Inorg Chem, 16, 1123, 10.1007/s00775-011-0797-4 2002, Human vitamin and mineral requirements Sian, 1996, Zinc absorption and intestinal losses of endogenous zinc in young Chinese women with marginal zinc intakes, Am J Clin Nutr, 63, 348, 10.1093/ajcn/63.3.348 Jankowski, 1994, Maintenance of normal intestinal mucosa: function, structure and adaption, Gut, 35, S1, 10.1136/gut.35.1_Suppl.S1 Menzies, 1999, Geography of intestinal permeability and absorption, Gut, 44, 483, 10.1136/gut.44.4.483 Veitch, 2001, Tropical enteropathy: a T-cell-mediated crypt hyperplastic enteropathy, Eur J Gastroenterol Hepatol, 13, 1175, 10.1097/00042737-200110000-00009 Rao, 2011, Urine sugars for in vivo gut permeability: validation and comparisons in irritable bowel syndrome-diarrhoea and controls, Am J Physiol Gastrointest Liver Physiol, 301, G919, 10.1152/ajpgi.00168.2011 Bjarnason, 1995, Intestinal permeability: an overview, Gastroenterology, 108, 1566, 10.1016/0016-5085(95)90708-4 Ziegler, 2003, Trophic and cytoprotective nutrition for intestinal adaption, mucosal repair and barrier function, Annu Rev Nutr, 23, 229, 10.1146/annurev.nutr.23.011702.073036 Brown, 1981, Relationship of the xylose absorption status of children in Bangladesh to their absorption of macronutrients from local diets, Am J Clin Nutr, 34, 1540, 10.1093/ajcn/34.8.1540 Manary, 2002, Zinc homeostasis in Malawian children consuming a high-phytate, maize-based diet, Am J Clin Nutr, 75, 1057, 10.1093/ajcn/75.6.1057 Manary, 2010, Perturbed zinc homeostasis in rural 3–5-y-old Malawian children is associated with abnormalities in intestinal permeability attributed to tropical enteropathy, Pediatr Res, 67, 671, 10.1203/PDR.0b013e3181da44dc Tran, 2011, Zinc homeostasis and gut function in children with coeliac disease, Am J Clin Nutr, 94, 1026, 10.3945/ajcn.111.018093 Crofton, 1990, Zinc metabolism in celiac disease, Am J Clin Nutr, 52, 379, 10.1093/ajcn/52.2.379 Goto, 1999, Epidemiology of altered intestinal permeability to lactulose and mannitol in Guatemalan infants, J Pediatr Gastroenterol Nutr, 28, 282, 10.1097/00005176-199903000-00013 Chen, 2003, Association of vitamin A and zinc status with intestinal permeability: analysis of cohort data from northeastern Brazil, J Health Popul Nutr, 21, 309 Koo, 1977, Effect of zinc deficiency on the ultra- structure of the pancreatic acinar cell and intestinal epithelium in the rat, J Nutr, 107, 896, 10.1093/jn/107.5.896 Ying, 2011, Effect of zinc deficiency on intestinal mucosal morphology and digestive enzyme activity in growing rat, Zhonghua Er Ke Za Zhi, 49, 249 Jing, 2009, Effects of zinc levels on activities of gastrointestinal enzymes in growing rats, J Anim Physiol Anim Nutr (Berl), 93, 606, 10.1111/j.1439-0396.2008.00843.x Wapnir, 2000, Zinc deficiency, malnutrition and the gastrointestinal tract, J Nutr, 130, S1388, 10.1093/jn/130.5.1388S Korpe, 2012, Environmental enteropathy: critical implications of a poorly understood condition, Trends Mol Med, 18, 328, 10.1016/j.molmed.2012.04.007 Hennig, 1992, Zinc deficiency alters barrier function of cultured porcine endothelial cells, J Nutr, 122, 1242, 10.1093/jn/122.6.1242 Hennig, 1993, Zinc protects against tumor necrosis factor-induced disruption of porcine endothelial cell monolayer integrity, J Nutr, 123, 1003 Hu, 2012, Zinc oxide-montmorillonite hybrid influences diarrhea, intestinal mucosal integrity and digestive enzyme activity in weaned pigs, Biol Trace Elem Res, 149, 190, 10.1007/s12011-012-9422-9 Zhang, 2009, Supplemental zinc reduced intestinal permeability by enhancing occluding and zonula occludens protein-1 expression in weaning piglets, Br J Nutr, 102, 687, 10.1017/S0007114509289033 Sturniolo, 2002, Effect of zinc supplementation on intestinal permeability in experimental colitis, J Lab Clin Med, 139, 311, 10.1067/mlc.2002.123624 Rodriguez, 1996, Intestinal paracellular permeability during malnutrition in guinea pigs: effect of high dietary zinc, Gut, 39, 416, 10.1136/gut.39.3.416 Wang, 2013, Zinc supplementation modifies tight junctions and alters barrier function of CACO-2 human intestinal epithelial layers, Dig Dis Sci, 58, 77, 10.1007/s10620-012-2328-8 Bates, 1993, A trial of zinc supplementation in young Gambian children, Br J Nutr, 69, 243, 10.1079/BJN19930026 Roy, 1992, Impact of zinc supplementation on intestinal permeability in Bangladeshi children with acute diarrhoeal syndrome and persistent diarrhea syndrome, J Pediatr Gastroenterol Nutr, 15, 289, 10.1097/00005176-199210000-00010 Thurnham, 2000, Innate immunity, gut integrity and vitamin A in Gambian and Indian infants, J Infect Dis, 182, S23, 10.1086/315912 Bhutta, 2013, Interventions to address deaths from childhood pneumonia and diarrhea equitably: what works and at what cost?, Lancet, 381, 1417, 10.1016/S0140-6736(13)60648-0 Yakoob, 2011, Preventive zinc supplementation in developing countries: impact on mortality and morbidity due to diarrhea, pneumonia and malaria, BMC Public Health, 11, S23, 10.1186/1471-2458-11-S3-S23 Walker, 2010, Zinc for the treatment of diarrhoea: effect on diarrhoea morbidity, mortality and incidence of future episodes, Int J Epidemiol, 39, i63, 10.1093/ije/dyq023 Roselli, 2003, Zinc oxide protects cultured enterocytes from the damage induced by Escherichia coli, J Nutr, 133, 4077, 10.1093/jn/133.12.4077 Huang, 1999, Effect of zinc supplementation on Escherichia coli septicaemia in weaned pigs, Swine Health Prod., 7, 109 Alam, 1994, Enteric protein loss and intestinal permeability changes in children during acute shingellosis and after recover effect of zinc supplementation, Gut, 35, 1707, 10.1136/gut.35.12.1707 Fraker, 2000, The dynamic link between the integrity of the immune system and zinc status, J Nutr, 130, S1399, 10.1093/jn/130.5.1399S Scott, 2000, Zinc deficiency impairs immune responses against parasitic nematode infections at intestinal and systemic sites, J Nutr, 130, S1412, 10.1093/jn/130.5.1412S Prasad, 2009, Zinc: role in immunity, oxidative stress and chronic inflammation, Curr Opin Clin Nutr Metab Care, 12, 646, 10.1097/MCO.0b013e3283312956 Levine, 2010, Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine, BMC Biol, 8, 129, 10.1186/1741-7007-8-129 Ahmed, 2009, Enhanced immunogenicity of an oral inactivated cholera vaccine in infants in Bangladesh obtained by zinc supplementation and by temporary withholding breast-feeding, Vaccine, 27, 1433, 10.1016/j.vaccine.2008.12.036 Ahmed, 2009, CD4+ T-cell responses to an oral inactivated cholera vaccine in young children in a cholera endemic country and the enhancing effect of zinc supplementation, Vaccine, 28, 422, 10.1016/j.vaccine.2009.10.032 Finamore, 2008, Zinc deficiency induces membrane barrier damage and increases neutrophil transmigration in CACO-2 cells, J Nutr, 138, 1664, 10.1093/jn/138.9.1664 Altaf, 2002, Zinc supplementation in oral rehydration solutions: experimental assessment and mechanisms of action, J Am Coll Nutr, 21, 26, 10.1080/07315724.2002.10719190 Cui, 2003, The permissive effect of zinc deficiency on uroguanylin and inducible nitric oxide synthase gene upregulation in rat intestine induced by interleukin 1alpha is rapidly reversed by zinc repletion, J Nutr, 133, 51, 10.1093/jn/133.1.51 Folsom, 2012, Zinc as a modulator of chronic, inflammatory intestinal disorders with a focus on celiac disease, inflammatory bowel syndrome and Crohn's disease, J Nutr Food Sci., 2, e116 Taccioli, 2012, Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature, Oncogene, 31, 4550, 10.1038/onc.2011.592 Foster, 2012, Zinc and the regulation of inflammatory cytokines: Implications for cardiovascular disease, Nutrients., 4, 676, 10.3390/nu4070676 Costarelli, 2010, Distinctive modulation of inflammatory and metabolic parameters in relation to zinc nutritional status in adult overweight/obese subjects, J Nutr Biochem, 21, 432, 10.1016/j.jnutbio.2009.02.001 Clemons, 2004, AREDS Report No. 13: Association of mortality with ocular disorders and an intervention of high dose anti-oxidants and zinc in the age-related eye disease study, Arch Ophthalmol, 122, 716, 10.1001/archopht.122.5.716 Powell, 2000, The antioxidant properties of zinc, J Nutr, 130, S1447, 10.1093/jn/130.5.1447S