Interactions between Sox9 and β-catenin control chondrocyte differentiation
Tóm tắt
Chondrogenesis is a multistep process that is essential for endochondral bone formation. Previous results have indicated a role for β-catenin and Wnt signaling in this pathway. Here we show the existence of physical and functional interactions between β-catenin and Sox9, a transcription factor that is required in successive steps of chondrogenesis. In vivo, either overexpression of
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Tài liệu tham khảo
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