Integrated Control of Na Transport along the Nephron

Titze, 2014, Sodium balance is not just a renal affair, Curr Opin Nephrol Hypertens, 23, 101, 10.1097/01.mnh.0000441151.55320.c3

Reinhardt, 1967, [Studies in awake dogs on the regulation of the sodium balance. I. The significance of the extracellular space for the regulation of the daily sodium balance], Pflugers Arch Gesamte Physiol Menschen Tiere, 295, 266, 10.1007/BF01844106

He, 2013, Effect of longer-term modest salt reduction on blood pressure, Cochrane Database Syst Rev, 4, CD004937

Liu, 1986, Axial heterogeneity of bicarbonate, chloride, and water transport in the rat proximal convoluted tubule. Effects of change in luminal flow rate and of alkalemia, J Clin Invest, 78, 1547, 10.1172/JCI112747

Frömter, 1973, Phenomenologic description of Na+, Cl- and HCO-3 absorption from proximal tubules of rat kidney, Pflugers Arch, 343, 189, 10.1007/BF00586045

Amasheh, 2002, Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells, J Cell Sci, 115, 4969, 10.1242/jcs.00165

Muto, 2010, Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules, Proc Natl Acad Sci U S A, 107, 8011, 10.1073/pnas.0912901107

Rosenthal, 2010, Claudin-2, a component of the tight junction, forms a paracellular water channel, J Cell Sci, 123, 1913, 10.1242/jcs.060665

Schnermann, 2013, Fluid reabsorption in proximal convoluted tubules of mice with gene deletions of claudin-2 and/or aquaporin1, Am J Physiol Renal Physiol, 305, F1352, 10.1152/ajprenal.00342.2013

Wright, 1974, Interference with feedback control of glomerular filtration rate by furosemide, triflocin, and cyanide, J Clin Invest, 53, 1695, 10.1172/JCI107721

Costanzo, 1984, Comparison of calcium and sodium transport in early and late rat distal tubules: effect of amiloride, Am J Physiol, 246, F937

Ellison, 1989, Adaptation of the distal convoluted tubule of the rat. Structural and functional effects of dietary salt intake and chronic diuretic infusion, J Clin Invest, 83, 113, 10.1172/JCI113847

Malnic, 1966, Micropuncture study of distal tubular potassium and sodium transport in rat nephron, Am J Physiol, 211, 529, 10.1152/ajplegacy.1966.211.3.529

Wang, 2001, Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron, Am J Physiol Renal Physiol, 281, F1117, 10.1152/ajprenal.2001.281.6.F1117

Wang, 1996, Effects of angiotensin II on electrolyte transport in the early and late distal tubule in rat kidney, Am J Physiol, 271, F143

Wang, 1993, Renal bicarbonate reabsorption in the rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule, J Clin Invest, 91, 2776, 10.1172/JCI116519

Almeida, 1982, Sodium transport in the rabbit connecting tubule, Am J Physiol, 243, F330

Shareghi, 1978, Calcium transport across segments of the rabbit distal nephron in vitro, Am J Physiol, 235, F367

Frindt, 2004, Na channels in the rat connecting tubule, Am J Physiol Renal Physiol, 286, F669, 10.1152/ajprenal.00381.2003

Nesterov, 2012, Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron, Am J Physiol Renal Physiol, 303, F1289, 10.1152/ajprenal.00247.2012

Loffing, 2000, Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets, Am J Physiol Renal Physiol, 279, F252, 10.1152/ajprenal.2000.279.2.F252

Reif, 1986, Sodium transport by rat cortical collecting tubule. Effects of vasopressin and desoxycorticosterone, J Clin Invest, 77, 1291, 10.1172/JCI112433

Tomita, 1985, Control of sodium and potassium transport in the cortical collecting duct of the rat. Effects of bradykinin, vasopressin, and deoxycorticosterone, J Clin Invest, 76, 132, 10.1172/JCI111935

Pácha, 1993, Regulation of Na channels of the rat cortical collecting tubule by aldosterone, J Gen Physiol, 102, 25, 10.1085/jgp.102.1.25

Palmer, 1986, Amiloride-sensitive Na channels from the apical membrane of the rat cortical collecting tubule, Proc Natl Acad Sci U S A, 83, 2767, 10.1073/pnas.83.8.2767

Leviel, 2010, The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice, J Clin Invest, 120, 1627, 10.1172/JCI40145

Frindt, 2007, Na channel expression and activity in the medullary collecting duct of rat kidney, Am J Physiol Renal Physiol, 292, F1190, 10.1152/ajprenal.00399.2006

Stokes, 1981, Heterogeneity of the rabbit collecting tubule: Localization of mineralocorticoid hormone action to the cortical portion, Kidney Int, 20, 340, 10.1038/ki.1981.144

Sands, 1988, Hormone effects on NaCl permeability of rat inner medullary collecting duct, Am J Physiol, 255, F421

Kudo, 1990, Effect of vasopressin on sodium transport across inner medullary collecting duct, Am J Physiol, 258, F1438

Rocha, 1990, Atrial peptide and cGMP effects on NaCl transport in inner medullary collecting duct, Am J Physiol, 259, F258

Ullrich, 1979, Sodium reabsorption in the papillary collecting duct of rats. Effect of adrenalectomy, low Na+ diet, acetazolamide, HCO-3-free solutions and of amiloride, Pflugers Arch, 379, 49, 10.1007/BF00622904

Sonnenberg, 1987, Effects of amiloride in the medullary collecting duct of rat kidney, Kidney Int, 31, 1121, 10.1038/ki.1987.117

Mancilha-Carvalho, 1989, Blood pressure and electrolyte excretion in the Yanomamo Indians, an isolated population, J Hum Hypertens, 3, 309

Grantham, 1970, The nature of transtubular Na and K transport in isolated rabbit renal collecting tubules, J Clin Invest, 49, 1815, 10.1172/JCI106399

Imai, 1990, Electrophysiological study of inner medullary collecting duct of hamsters, Pflugers Arch, 416, 180, 10.1007/BF00370240

Sonnenberg, 1986, Atrial natriuretic factor inhibits sodium transport in medullary collecting duct, Am J Physiol, 250, F963

Erlij, 1976, Basic electrical properties of tight epithelia determined with a simple method, Pflugers Arch, 364, 91, 10.1007/BF01062917

Higgins, 1977, Electrical properties of amphibian urinary bladder epithelia. II. The cell potential profile in necturus maculosus, Pflugers Arch, 371, 87, 10.1007/BF00580776

Lewis, 1976, The mechanism of Na+ transport by rabbit urinary bladder, J Membr Biol, 28, 41, 10.1007/BF01869690

Landwehr, 1968, Effect of reduction in filtration rate on renal tubular sodium and water reabsorption, Am J Physiol, 215, 687, 10.1152/ajplegacy.1968.215.3.687

Lindheimer, 1967, Evidence that an acute increase in glomerular filtration has little effect on sodium excretion in the dog unless extracellular volume is expanded, J Clin Invest, 46, 256, 10.1172/JCI105528

Glabman, 1965, Micropuncture study of the effect of acute reductions in glomerular filtration rate on sodium and water reabsorption by the proximal tubules of the rat, J Clin Invest, 44, 1410, 10.1172/JCI105246

Schnermann, 1968, Balance between tubular flow rate and net fluid reabsorption in the proximal convolution of the rat kidney. I. Dependency of reabsorptive net fluid flux upon proximal tubular surface area at spontaneous variations of filtration rate, Pflugers Arch, 304, 90, 10.1007/BF00586722

Brenner, 1971, Postglomerular vascular protein concentration: Evidence for a causal role in governing fluid reabsorption and glomerulotublar balance by the renal proximal tubule, J Clin Invest, 50, 336, 10.1172/JCI106501

Brenner, 1971, On the mechanism of inhibition in fluid reabsorption by the renal proximal tubule of the volume-expanded rat, J Clin Invest, 50, 1596, 10.1172/JCI106647

Falchuk, 1971, Oncotic and hydrostatic pressures in peritubular capillaries and fluid reabsorption by proximal tubule, Am J Physiol, 220, 1427, 10.1152/ajplegacy.1971.220.5.1427

Lewy, 1968, Peritubular control of proximal tubular fluid reabsorption in the rat kidney, Am J Physiol, 214, 943, 10.1152/ajplegacy.1968.214.5.943

Barfuss, 1979, Flow dependence of nonelectrolyte absorption in the nephron, Am J Physiol, 236, F163

Burg, 1976, Organic solutes in fluid absorption by renal proximal convoluted tubules, Am J Physiol, 231, 627, 10.1152/ajplegacy.1976.231.2.627

Bartoli, 1973, Effect of intraluminal flow on proximal tubular reabsorption, J Clin Invest, 52, 843, 10.1172/JCI107248

Du, 2004, Mechanosensory function of microvilli of the kidney proximal tubule, Proc Natl Acad Sci U S A, 101, 13068, 10.1073/pnas.0405179101

Du, 2006, Axial flow modulates proximal tubule NHE3 and H-ATPase activities by changing microvillus bending moments, Am J Physiol Renal Physiol, 290, F289, 10.1152/ajprenal.00255.2005

Wright, 1982, Flow-dependent transport processes: Filtration, absorption, secretion, Am J Physiol, 243, F1

Briggs, 1982, A simple steady-state model for feedback control of glomerular filtration rate, Kidney Int Suppl, 12, S143

Briggs, 1984, Quantitative characterization of the tubuloglomerular feedback response: effect of growth, Am J Physiol, 247, F808

Moore, 1983, Perturbation analysis of tubuloglomerular feedback in hydropenic and hemorrhaged rats, Am J Physiol, 245, F554

Thomson, 1993, Homeostatic efficiency of tubuloglomerular feedback in hydropenia, euvolemia, and acute volume expansion, Am J Physiol, 264, F930

Moore, 1979, Feedback mediation of SNGFR autoregulation in hydropenic and DOCA- and salt-loaded rats, Am J Physiol, 237, F63

Navar, 1974, Distal tubular feedback in the autoregulation of single nephron glomerular filtration rate, J Clin Invest, 53, 516, 10.1172/JCI107585

Holstein-Rathlou, 1991, Tubuloglomerular feedback dynamics and renal blood flow autoregulation in rats, Am J Physiol, 260, F53

Lorenz, 1999, Micropuncture analysis of single-nephron function in NHE3-deficient mice, Am J Physiol, 277, F447

Schnermann, 1998, Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice, Proc Natl Acad Sci U S A, 95, 9660, 10.1073/pnas.95.16.9660

Gurley, 2011, AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure, Cell Metab, 13, 469, 10.1016/j.cmet.2011.03.001

Manoli, 2013, Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia, Proc Natl Acad Sci U S A, 110, 13552, 10.1073/pnas.1302764110

Tucker, 1978, Studies on the tubulo-glomerular feedback system in the rat. The mechanism of reduction in filtration rate with benzolamide, J Clin Invest, 62, 993, 10.1172/JCI109229

Seney, 1987, Modification of tubuloglomerular feedback signal by dietary protein, Am J Physiol, 252, F83

Thomson, 2004, Early diabetes as a model for testing the regulation of juxtaglomerular NOS I, Am J Physiol Renal Physiol, 287, F732, 10.1152/ajprenal.00340.2003

Morgan, 1969, A study by continuous microperfusion of water and electrolyte movements in the loop of Henle and distal tubule of the rat, Nephron, 6, 388, 10.1159/000179741

Greger, 1985, Ion transport mechanisms in thick ascending limb of Henle’s loop of mammalian nephron, Physiol Rev, 65, 760, 10.1152/physrev.1985.65.3.760

Jensen, 2007, Flow-induced [Ca2+]i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron, J Am Soc Nephrol, 18, 2062, 10.1681/ASN.2006070700

Praetorius, 2013, Primary cilium-dependent sensing of urinary flow and paracrine purinergic signaling, Semin Cell Dev Biol, 24, 3, 10.1016/j.semcdb.2012.10.003

Cabral, 2012, ATP mediates flow-induced NO production in thick ascending limbs, Am J Physiol Renal Physiol, 303, F194, 10.1152/ajprenal.00504.2011

Wang, 1997, Phospholipase A2 is involved in mediating the effect of extracellular Ca2+ on apical K+ channels in rat TAL, Am J Physiol, 273, F421

Ellison, 1987, Thiazide-sensitive sodium chloride cotransport in early distal tubule, Am J Physiol, 253, F546

Monroy, 2000, Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: A new model for ions and diuretics interaction, Am J Physiol Renal Physiol, 279, F161, 10.1152/ajprenal.2000.279.1.F161

Engbretson, 1987, Flow-dependent potassium secretion by rabbit cortical collecting tubule in vitro, Am J Physiol, 253, F896

Woda, 2001, Flow-dependent K+ secretion in the cortical collecting duct is mediated by a maxi-K channel, Am J Physiol Renal Physiol, 280, F786, 10.1152/ajprenal.2001.280.5.F786

Carattino, 2004, Epithelial Na+ channels are activated by laminar shear stress, J Biol Chem, 279, 4120, 10.1074/jbc.M311783200

Ma, 2002, ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells, Am J Physiol Renal Physiol, 282, F501, 10.1152/ajprenal.00147.2001

Pochynyuk, 2008, Purinergic control of apical plasma membrane PI(4,5)P2 levels sets ENaC activity in principal cells, Am J Physiol Renal Physiol, 294, F38, 10.1152/ajprenal.00403.2007

Stanton, 1989, Regulation of renal ion transport and cell growth by sodium, Am J Physiol, 257, F1

Kaissling, 1988, Adaptation of distal tubule and collecting duct to increased sodium delivery. I. Ultrastructure, Am J Physiol, 255, F1256

Kaissling, 1990, Functional morphology of kidney tubules and cells in situ, Methods Enzymol, 191, 265, 10.1016/0076-6879(90)91018-2

Lalioti, 2006, Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule, Nat Genet, 38, 1124, 10.1038/ng1877

Yang, 2007, Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model, Cell Metab, 5, 331, 10.1016/j.cmet.2007.03.009

Schultheis, 1998, Phenotype resembling Gitelman’s syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule, J Biol Chem, 273, 29150, 10.1074/jbc.273.44.29150

Wade, 1990, Morphological and physiological responses to aldosterone: Time course and sodium dependence, Am J Physiol, 259, F88

Palmer, 1993, Regulation of the Na-K pump of the rat cortical collecting tubule by aldosterone, J Gen Physiol, 102, 43, 10.1085/jgp.102.1.43

Schor, 1980, Glomerular adaptations to chronic dietary salt restriction or excess, Am J Physiol, 238, F428

Vallon, 2002, Salt-sensitivity of proximal reabsorption alters macula densa salt and explains the paradoxical effect of dietary salt on glomerular filtration rate in diabetes mellitus, J Am Soc Nephrol, 13, 1865, 10.1097/01.ASN.0000016441.41118.57

Bello-Reuss, 1975, Effects of acute unilateral renal denervation in the rat, J Clin Invest, 56, 208, 10.1172/JCI108069

Cogan, 1990, Angiotensin II: A powerful controller of sodium transport in the early proximal tubule, Hypertension, 15, 451, 10.1161/01.HYP.15.5.451

Geibel, 1990, Angiotensin II stimulates both Na(+)-H+ exchange and Na+/HCO3- cotransport in the rabbit proximal tubule, Proc Natl Acad Sci U S A, 87, 7917, 10.1073/pnas.87.20.7917

Schuster, 1984, Angiotensin II directly stimulates sodium transport in rabbit proximal convoluted tubules, J Clin Invest, 73, 507, 10.1172/JCI111237

Aperia, 1987, Dopamine causes inhibition of Na+-K+-ATPase activity in rat proximal convoluted tubule segments, Am J Physiol, 252, F39

Osgood, 1978, Further studies on segmental sodium transport in the rat kidney during expansion of the extracellular fluid volume, J Clin Invest, 62, 311, 10.1172/JCI109131

Li, 2011, Renal proximal tubule angiotensin AT1A receptors regulate blood pressure, Am J Physiol Regul Integr Comp Physiol, 301, R1067, 10.1152/ajpregu.00124.2011

Frindt, 2009, Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium, Am J Physiol Renal Physiol, 297, F1249, 10.1152/ajprenal.00401.2009

Kim, 1998, The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein, Proc Natl Acad Sci U S A, 95, 14552, 10.1073/pnas.95.24.14552

van der Lubbe, 2012, Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway, Pflugers Arch, 463, 853, 10.1007/s00424-012-1104-0

Wang, 2001, The renal thiazide-sensitive Na-Cl cotransporter as mediator of the aldosterone-escape phenomenon, J Clin Invest, 108, 215, 10.1172/JCI10366

van der Lubbe, 2011, Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosterone, Kidney Int, 79, 66, 10.1038/ki.2010.290

Schwartz, 1978, Mineralocorticoid effects on cation transport by cortical collecting tubules in vitro, Am J Physiol, 235, F576

Mamenko, 2012, Angiotensin II increases activity of the epithelial Na+ channel (ENaC) in distal nephron additively to aldosterone, J Biol Chem, 287, 660, 10.1074/jbc.M111.298919

Mamenko, 2013, Chronic angiotensin II infusion drives extensive aldosterone-independent epithelial Na+ channel activation, Hypertension, 62, 1111, 10.1161/HYPERTENSIONAHA.113.01797

Nonoguchi, 1989, ANF inhibits NaCl and fluid absorption in cortical collecting duct of rat kidney, Am J Physiol, 256, F179

Maack, 1996, Role of atrial natriuretic factor in volume control, Kidney Int, 49, 1732, 10.1038/ki.1996.257

Zeidel, 1986, Atrial peptides inhibit oxygen consumption in kidney medullary collecting duct cells, Am J Physiol, 251, F379

van Buren, 1992, Effects of acute NaCl, KCl and KHCO3 loads on renal electrolyte excretion in humans, Clin Sci (Lond, 83, 567, 10.1042/cs0830567

Wright, 1971, Potassium secretion by distal tubule after potassium adaptation, Am J Physiol, 221, 437, 10.1152/ajplegacy.1971.221.2.437

Brandis, 1972, Potassium-induced inhibition of proximal tubular fluid reabsorption in rats, Am J Physiol, 222, 421, 10.1152/ajplegacy.1972.222.2.421

Stokes, 1982, Consequences of potassium recycling in the renal medulla. Effects of ion transport by the medullary thick ascending limb of Henle’s loop, J Clin Invest, 70, 219, 10.1172/JCI110609

Sorensen, 2013, Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice, Kidney Int, 83, 811, 10.1038/ki.2013.14

Vallon, 2009, Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1, Am J Physiol Renal Physiol, 297, F704, 10.1152/ajprenal.00030.2009

Frindt, 2010, Effects of dietary K on cell-surface expression of renal ion channels and transporters, Am J Physiol Renal Physiol, 299, F890, 10.1152/ajprenal.00323.2010

Palmer, 1994, Regulation of apical K and Na channels and Na/K pumps in rat cortical collecting tubule by dietary K, J Gen Physiol, 104, 693, 10.1085/jgp.104.4.693

Frindt, 2009, Dietary K regulates ROMK channels in connecting tubule and cortical collecting duct of rat kidney, Am J Physiol Renal Physiol, 296, F347, 10.1152/ajprenal.90527.2008

Wang, 1990, Regulation of small-conductance K+ channel in apical membrane of rat cortical collecting tubule, Am J Physiol, 259, F494

Frindt, 2011, Conservation of Na+ vs. K+ by the rat cortical collecting duct, Am J Physiol Renal Physiol, 301, F14, 10.1152/ajprenal.00705.2010

Kotchen, 1983, Effects of NaCl on renin and aldosterone responses to potassium depletion, Am J Physiol, 244, E164