Insights into molecular mechanisms of contact hypersensitivity gained from gene knockout studies
Tóm tắt
Từ khóa
Tài liệu tham khảo
Albert, 1998, Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs, Nature, 392, 86, 10.1038/32183
Banchereau, 2000, Immunobiology of dendritic cells, Annu. Rev. Immunol., 18, 767, 10.1146/annurev.immunol.18.1.767
Stingl, 1999, Dermatology in General Medicine, 5th, 343
Grabbe, 1998, Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity, Immunol. Today, 19, 37, 10.1016/S0167-5699(97)01186-9
Koller, 1992, Altering genes in animals by gene targeting, Annu. Rev. Immunol., 10, 705, 10.1146/annurev.iy.10.040192.003421
Shwartz, 1992, Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy, Cell, 71, 1065, 10.1016/S0092-8674(05)80055-8
Szczepanik, 1996, γδ T cells from tolerized αβ T cell receptor (TCR)-deficient mice inhibit contact sensitivity-effector T cells in vivo, and their interferon-gamma production in vitro. J. Exp, Med., 184, 2129
Bour, 1995, Major histocompatibility complex class I-restricted CD8+ T cells and class II-restricted CD4+ T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene, Eur. J. Immunol., 25, 3006, 10.1002/eji.1830251103
Girardi, 2000, Augmented allergic and irritant dermatitis in γδ+ T-cell deficient mice is dependent on genetic background, J. Invest. Dermatol., 114, 762
Tsuji, 2000, Early local generation of C5a initiates the elicitation of contact sensitivity by leading to early T cell recruitment, J. Immunol., 165, 1588, 10.4049/jimmunol.165.3.1588
Kondo, 1996, Hyporesponsiveness in contact hypersensitivity and irritant contact dermatitis in CD4 gene targeted mouse, J. Invest. Dermatol., 106, 993, 10.1111/1523-1747.ep12338505
Schwarz, 1998, Interleukin 12 breaks ultraviolet light induced immunosuppression by affecting CD8+ rather than CD4+ T cells, J. Invest. Dermatol., 110, 272, 10.1046/j.1523-1747.1998.00111.x
Wang, 2000, CD4+ Th1 and CD8+ type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity, J. Immunol., 165, 6783, 10.4049/jimmunol.165.12.6783
Lenschow, 1996, CD28/B7 system of T cell costimulation, Annu. Rev. Immunol., 14, 233, 10.1146/annurev.immunol.14.1.233
Shahinian, 1993, Differential T cell costimulatory requirements in CD28-deficient mice, Science, 261, 609, 10.1126/science.7688139
Rauschmayr-Kopp, 1998, Distinct roles for B7 costimulation in contact hypersensitivity and humoral immune responses to epicutaneous antigen, Eur. J. Immunol., 28, 4221, 10.1002/(SICI)1521-4141(199812)28:12<4221::AID-IMMU4221>3.0.CO;2-M
Kondo, 1996, Contribution of the CD28 molecule to allergic and irritant-induced skin reactions in CD28–/– mice, J. Immunol., 157, 4822, 10.4049/jimmunol.157.11.4822
Chen, 1999, Ox40-ligand has a critical costimulatory role in dendritic cell: T cell interactions, Immunity, 11, 689, 10.1016/S1074-7613(00)80143-0
Moodycliffe, 2000, CD40-CD40 ligand interactions in vivo regulate migration of antigen-bearing dendritic cells from the skin to draining lymph nodes, J. Exp. Med., 191, 2011, 10.1084/jem.191.11.2011
Xu, 1996, Impaired primary T cell responses in L-selectin-deficient mice, J. Exp. Med., 183, 589, 10.1084/jem.183.2.589
Tedder, 1995, L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites, J. Exp. Med., 181, 2259, 10.1084/jem.181.6.2259
Staite, 1996, Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin, Blood, 88, 2973, 10.1182/blood.V88.8.2973.bloodjournal8882973
Subramaniam, 1995, Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice, J. Exp. Med., 181, 2277, 10.1084/jem.181.6.2277
Schmits, 1996, LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor, J. Exp. Med., 183, 1415, 10.1084/jem.183.4.1415
de Fougerolles, 2000, Regulation of inflammation by collagen-binding integrin α1β1 and α2β2 in models of hypersensitivity and arthritis, J. Clin. Invest., 105, 721, 10.1172/JCI7911
Sligh, 1993, Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1, Proc. Natl. Acad. Sci. USA, 90, 8528, 10.1073/pnas.90.18.8529
Xu, 1994, Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice, J. Exp. Med., 180, 95, 10.1084/jem.180.1.95
Steeber, 1999, Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways, J. Immunol., 163, 2176, 10.4049/jimmunol.163.4.2176
Duncas, 1999, Genetic evidence for functional redundancy of platelet/endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions. J, Immunol., 162, 3022, 10.4049/jimmunol.162.5.3022
Sad, 1995, Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ cells secreting TH1 or TH2 cytokines, Immunity, 2, 271, 10.1016/1074-7613(95)90051-9
Dearman, 1992, Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone, Clin. Exp. Allergy, 22, 241, 10.1111/j.1365-2222.1992.tb03079.x
Tang, 1996, Suppression of murine allergic contact dermatitis by CTLA4Ig: tolerance induction of Th2 responses requires additional blockage of CD40-ligand, J. Immunol., 157, 117, 10.4049/jimmunol.157.1.117
Lu, 1998, Targeted disruption of the interferon-γ receptor 2 gene results in severe immune defects in mice, Proc. Natl. Acad. Sci. USA, 95, 8233, 10.1073/pnas.95.14.8233
Reeve, 1999, Interferon-γ is involved in photoimmunoprotection by UVA (320–400 nm) radiation in mice, J. Invest. Dermatol., 112, 945, 10.1046/j.1523-1747.1999.00594.x
Hope, 2000, Deficiency of IL-2 or IL-6 reduces lymphocyte proliferation, but only IL-6 deficiency decreases the contact hypersensitivity response, Eur. J. Immunol., 30, 197, 10.1002/1521-4141(200001)30:1<197::AID-IMMU197>3.0.CO;2-9
Berg, 1995, Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses, J. Exp. Med., 182, 99, 10.1084/jem.182.1.99
Wang, 1999, Enhanced epidermal Langerhans cell migration in IL-10 knockout mice, J. Immunol., 162, 277, 10.4049/jimmunol.162.1.277
Traidl, 1999, Inhibition of allergic contact dermatitis to DNFB but not to oxazolone in interleukin-4-deficient mice, J. Invest. Dermatol., 112, 476, 10.1046/j.1523-1747.1999.00550.x
Heufler, 1992, Cytokine gene expression in murine epidermal cell suspension: interleukin 1 beta and macrophage inflammatory protein 1 alpha are selectively expressed in Langerhans cells but are differently regulated in culture. J. Exp, Med., 176, 1221
Lanzavecchia, 2000, Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells, Science, 290, 92, 10.1126/science.290.5489.92
Shornick, 1996, Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzene, J. Exp. Med., 183, 1427, 10.1084/jem.183.4.1427
Zheng, 1995, Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice, Immunity, 3, 9, 10.1016/1074-7613(95)90154-X
Pasparakis, 1996, Immune and inflammatory responses in TNFα-deficient mice: a critical requirement for TNFα in the formation of primary B cell follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp, Med., 184, 1397
Kondo, 1995, Effect of gene-targeted mutation in TNF receptor (p55) on contact hypersensitivity and ultraviolet B-induced immunosuppression, J. Immunol., 155, 3801, 10.4049/jimmunol.155.8.3801
Wang, 1997, Depressed Langerhans cell migration and reduced contact hypersensitivity response in mice lacking TNF receptor p75, J. Immunol., 159, 6148, 10.4049/jimmunol.159.12.6148
Mach, 1998, Involvement of interleukin-3 in delayed-type hypersensitivity, Blood, 91, 778
Cyster, 1999, Chemokines and cell migration in secondary lymphoid organs, Science, 286, 2098, 10.1126/science.286.5447.2098
Mantovani, 1999, The chemokine system: redundancy for robust outputs, Immunol. Today, 20, 254, 10.1016/S0167-5699(99)01469-3
Lu, 1998, Abnormality in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice, J. Exp. Med., 187, 601, 10.1084/jem.187.4.601
Zhou, 1998, Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mice homologue of the major HIV-1 coreceptor, J. Immunol., 160, 4018, 10.4049/jimmunol.160.8.4018
Varona, 2001, CCR6-deficient mice have impaired leukocyte homeostasis and hypersensitivity responses, J. Clin. Invest., 107, R37, 10.1172/JCI11297
Forster, 1999, CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs, Cell, 99, 23, 10.1016/S0092-8674(00)80059-8
Tsuji, 1997, Required early complement activation in contact sensitivity with generation of local C5-dependent chemotactic activity, and late T cell interferon γ: a possible initiating role of B cells. J. Exp, Med., 186, 1015
Kehren, 1999, Cytotoxicity is mandatory for CD8+ T cell-mediated contact hypersensitivity, J. Exp. Med., 189, 779, 10.1084/jem.189.5.779
Beissert, 1998, Impaired cutaneous immune responses in Thy-1-deficient mice, J. Immunol., 161, 5296, 10.4049/jimmunol.161.10.5296
Wang, 1999, Matrix metalloproteinase deficiencies affect contact hypersensitivity: stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response. Proc. Natl. Acad. Sci, USA, 96, 6885, 10.1073/pnas.96.12.6885
Koyama, 1998, Effect of tenascin-C deficiency of chemically induced dermatitis in the mouse, J. Invest. Dermatol., 111, 930, 10.1046/j.1523-1747.1998.00401.x
Weih, 1995, Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family, Cell, 80, 331, 10.1016/0092-8674(95)90416-6
Yokozeki, 2000, Signal transducer and activator of transcription 6 is essential in the induction of contact hypersensitivity, J. Exp. Med., 191, 995, 10.1084/jem.191.6.995
Shreedhar, 1999, Dendritic cells require T cells for functional maturation in vivo, Immunity, 11, 625, 10.1016/S1074-7613(00)80137-5
Byrum, 1999, Determination of the contribution of cysteinyl leukotrienes and leukotriene B4 in acute inflammatory responses using 5-lipoxygenase- and leukotriene A4 hydrolase-deficient mice. J, Immunol., 163, 6810, 10.4049/jimmunol.163.12.6810
Thomas, 1999, Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase, J. Immunol., 163, 978, 10.4049/jimmunol.163.2.978
Kinet, 1999, The high affinity IgE receptor (FcɛR I): from physiology to pathology, Annu. Rev. Immunol., 17, 913, 10.1146/annurev.immunol.17.1.931
Wang, 1992, Epidermal Langerhans cells from normal human skin bind monomeric IgE via FcɛR I, J. Exp. Med., 175, 1353, 10.1084/jem.175.5.1353
Zhang, 2000, Chemical activation of innate and specific immunity in contact dermatitis, J. Invest. Dermatol., 115, 168, 10.1046/j.1523-1747.2000.00999.x
Scholzen, 2001, Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis, J. Immunol., 166, 1285, 10.4049/jimmunol.166.2.1285
Kadereit, 2001, Negative regulation of CD8+ T cell function by the IFN-induced and double-stranded RNA-activated kinase PKR, J. Immunol., 165, 6896, 10.4049/jimmunol.165.12.6896