Inhibition of Homologous Recombination and Promotion of Mutagenic Repair of DNA Double-Strand Breaks Underpins Arabinoside–Nucleoside Analogue Radiosensitization
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Iliakis, 1989, Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: comparison with fixation of PLD, Int J Radiat Oncol Biol Phys, 16, 1261, 10.1016/0360-3016(89)90295-2
Iliakis, 1985, Evidence for the induction of two types of potentially lethal damage after exposure of plateau phase Chinese hamster V79 cells to γ-rays, Radiat Environ Biophys, 24, 185, 10.1007/BF01209522
Iliakis, 1983, Effects of the nucleoside analogues alpha-ara A, beta-ara A and beta-ara C on cell growth and repair of both potentially lethal damage and DNA double strand breaks in mammalian cells in culture, Anticancer Res, 3, 143
Mustafi, 1994, Enhancement of X-ray toxicity in squamous cell carcinoma cell lines by DNA polymerase inhibitors, Int J Radiat Biol, 65, 675, 10.1080/09553009414550791
Ewald, 2008, Nucleoside analogs: molecular mechanisms signaling cell death, Oncogene, 27, 6522, 10.1038/onc.2008.316
McGinn, 2001, Recent advances in the use of radiosensitizing nucleosides, Semin Radiat Oncol, 11, 270, 10.1053/srao.2001.26002
Mladenov, 2013, DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy, Front Oncol, 3, 113, 10.3389/fonc.2013.00113
Lieber, 2010, The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway, Annu Rev Biochem, 79, 181, 10.1146/annurev.biochem.052308.093131
Mao, 2008, Comparison of nonhomologous end joining and homologous recombination in human cells, DNA Repair, 7, 1765, 10.1016/j.dnarep.2008.06.018
Soni, 2014, Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining, Nucleic Acids Res, 42, 6380, 10.1093/nar/gku298
Xie, 2009, Role of mammalian Mre11 in classical and alternative nonhomologous end joining, Nat Struct Mol Biol, 16, 814, 10.1038/nsmb.1640
Lee-Theilen, 2011, CtIP promotes microhomology-mediated alternative end joining during class-switch recombination, Nat Struct Mol Biol, 18, 75, 10.1038/nsmb.1942
Wu, 2008, Enhanced use of backup pathways of NHEJ in G2 in Chinese hamster mutant cells with defects in the classical pathway of NHEJ, Radiat Res, 170, 512, 10.1667/RR1456.1
Simsek, 2011, DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation, PLoS Genet, 7, e1002080, 10.1371/journal.pgen.1002080
Zhang, 2011, An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway, Nat Struct Mol Biol, 18, 80, 10.1038/nsmb.1940
Wray, 2013, PARP1 is required for chromosomal translocations, Blood, 121, 4359, 10.1182/blood-2012-10-460527
Heyer, 2010, Regulation of homologous recombination in eukaryotes, Annu Rev Genet, 44, 113, 10.1146/annurev-genet-051710-150955
Hinz, 2005, Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells, DNA Repair, 4, 782, 10.1016/j.dnarep.2005.03.005
Qiao, 2013, Imatinib radiosensitizes bladder cancer by targeting homologous recombination, Cancer Res, 73, 1611, 10.1158/0008-5472.CAN-12-1170
Fishman-Lobell, 1992, Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated, Mol Cell Biol, 12, 1292
Stark, 2004, Genetic steps of mammalian homologous repair with distinct mutagenic consequences, Mol Cell Biol, 24, 9305, 10.1128/MCB.24.21.9305-9316.2004
Costantino, 2014, Break-induced replication repair of damaged forks induces genomic duplications in human cells, Science, 343, 88, 10.1126/science.1243211
Shahar, 2012, Live imaging of induced and controlled DNA double-strand break formation reveals extremely low repair by homologous recombination in human cells, Oncogene, 31, 3495, 10.1038/onc.2011.516
Rothkamm, 2003, Pathways of DNA double-strand break repair during the mammalian cell cycle, Mol Cell Biol, 23, 5706, 10.1128/MCB.23.16.5706-5715.2003
Helleday, 2010, Homologous recombination in cancer development, treatment and development of drug resistance, Carcinogenesis, 31, 955, 10.1093/carcin/bgq064
Riballo, 1999, Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient, Curr Biol, 9, 699, 10.1016/S0960-9822(99)80311-X
Gunn, 2012, I-SceI-based assays to examine distinct repair outcomes of mammalian chromosomal double strand breaks, Methods Mol Biol, 920, 379, 10.1007/978-1-61779-998-3_27
Bindra, 2013, Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells, Nucleic Acids Res, 41, e115, 10.1093/nar/gkt255
Castro, 2013, High-throughput SNP-based authentication of human cell lines, Int J Cancer, 132, 308, 10.1002/ijc.27675
Iliakis, 1988, Differences in inhibition by beta-arabinofuranosyladenine (araA) of radiation induced DNA damage repair in exponentially growing and plateau-phase CHO-cells, Radiat Environ Biophys, 27, 295, 10.1007/BF01209758
Wang, 2001, Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group, Oncogene, 20, 2212, 10.1038/sj.onc.1204350
Iliakis, 2004, Mechanisms of DNA double strand break repair and chromosome aberration formation, Cytogenet Genome Res, 104, 14, 10.1159/000077461
Ewald, 2007, H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation, Mol Cancer Ther, 6, 1239, 10.1158/1535-7163.MCT-06-0633
Gagou, 2010, Enhanced H2AX phosphorylation, DNA replication fork arrest, and cell death in the absence of Chk1, Mol Biol Cell, 21, 739, 10.1091/mbc.e09-07-0618
Raderschall, 1999, Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage, Proc Natl Acad Sci U S A, 96, 1921, 10.1073/pnas.96.5.1921
Scully, 1997, Association of BRCA1 with Rad51 in mitotic and meiotic cells, Cell, 88, 265, 10.1016/S0092-8674(00)81847-4
Gasior, 2001, Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis, Proc Natl Acad Sci U S A, 98, 8411, 10.1073/pnas.121046198
Tebbs, 1995, Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene, Proc Natl Acad Sci U S A, 92, 6354, 10.1073/pnas.92.14.6354
Feng, 2011, Rad52 inactivation is synthetically lethal with BRCA2 deficiency, Proc Natl Acad Sci U S A, 108, 686, 10.1073/pnas.1010959107
Liu, 2011, Berberine radiosensitizes human esophageal cancer cells by downregulating homologous recombination repair protein RAD51, PLoS ONE, 6, e23427, 10.1371/journal.pone.0023427
Short, 2011, Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+tumor-derived cells, Neuro Oncol, 13, 487, 10.1093/neuonc/nor010
Jensen, 2013, BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage, DNA Repair, 12, 306, 10.1016/j.dnarep.2012.12.007
Mozdarani, 1987, The effect of 9-beta-D-arabinofuranosyladenine on the formation of X-ray induced chromatid aberrations in X-irradiated G2 human cells, Mutagenesis, 2, 371, 10.1093/mutage/2.5.371
Wachters, 2003, Selective targeting of homologous DNA recombination repair by gemcitabine, Int J Radiat Oncol Biol Phys, 57, 553, 10.1016/S0360-3016(03)00503-0
Bergs, 2013, Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining, DNA Repair, 12, 38, 10.1016/j.dnarep.2012.10.008
Lepage, 1975, 9-beta-D-arabinofuranosyladenine 5′-phosphate metabolism and excretion in humans, Cancer Res, 35, 3036
Fauvelle, 1991, Diclofenac, paracetamol, and vidarabine removal during plasma exchange in polyarteritis nodosa patients, Biopharm Drug Dispos, 12, 411, 10.1002/bdd.2510120603
Gregoire, 2002, A phase I study of fludarabine combined with radiotherapy in patients with intermediate to locally advanced head and neck squamous cell carcinoma, Radiother Oncol, 63, 187, 10.1016/S0167-8140(02)00024-5