Inhibition of Ca2+-Independent Phospholipase A2 Results in Insufficient Insulin Secretion and Impaired Glucose Tolerance
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Six, 2000, The expanding superfamily of phospholipase A2 enzymes: classification and characterization., Biochim Biophys Acta, 1488, 1, 10.1016/S1388-1981(00)00105-0
Metz, 1987, Pancreatic islet phospholipase A2: differential, Ca2+-dependent effects of lysophospholipids, arachidonic acid, and its lipoxygenase-derived metabolites on insulin release., Adv Prostaglandin Thromboxane Leukot Res, 17B, 668
Jones, 1993, Arachidonic acid as a second messenger in glucose-induced insulin secretion from pancreatic β-cells., J Endocrinol, 137, 7, 10.1677/joe.0.1370007
Turk, 1993, Amplification of insulin secretion by lipid messengers., Diabetes, 42, 367, 10.2337/diab.42.3.367
Ma, 2001, The molecular biology of the group VIA Ca2+-independent phospholipase A2., Prog Nucleic Acid Res Mol Biol, 67, 1, 10.1016/S0079-6603(01)67023-5
Simonsson, 1998, Ca2+-independent phospholipase A2 contributes to the insulinotropic action of cholecystokinin-8 in rat islets: dissociation from the mechanism of carbachol., Diabetes, 47, 1436, 10.2337/diabetes.47.9.1436
Ehses, 2001, A new pathway for glucose-dependent insulinotropic polypeptide (GIP) receptor signaling: evidence for the involvement of phospholipase A2 in GIP-stimulated insulin secretion., J Biol Chem, 276, 23667, 10.1074/jbc.M103023200
Konrad, 1992, Carbachol stimulation of phospholipase A2 and insulin secretion in pancreatic islets., Biochem J, 287, 283, 10.1042/bj2870283
Laychock, 1982, Phospholipase A2 activity in pancreatic islets is calcium-dependent and stimulated by glucose., Cell Calcium, 3, 43, 10.1016/0143-4160(82)90036-7
Kato, 1983, Possible involvement of phospholipase A2 activation and lipoxygenase product(s) in the mechanism of insulin secretion., Adv Prostaglandin Thromboxane Leukot Res, 12, 265
Metz, 1984, Is phospholipase A2 a “glucose sensor” responsible for the phasic pattern of insulin release?, Prostaglandins, 27, 147, 10.1016/0090-6980(84)90228-4
Dunlop, 1984, Activity of endogenous phospholipase C and phospholipase A2 in glucose stimulated pancreatic islets., Biochem Biophys Res Commun, 120, 820, 10.1016/S0006-291X(84)80180-1
Dunlop, 1995, Glucose-induced phosphorylation and activation of a high molecular weight cytosolic phospholipase A2 in neonatal rat pancreatic islets., Int J Biochem Cell Biol, 27, 1191, 10.1016/1357-2725(95)00093-5
Gagliardino, 1985, Role of phospholipase and calmodulin inhibitors on insulin, arachidonic acid and prostaglandin E2 release., Diabetes Res Clin Pract, 1, 327, 10.1016/S0168-8227(86)80045-6
Fujimoto, 1987, Phasic effects of glucose, phospholipase A2, and lysophospholipids on insulin secretion., Endocrinology, 120, 1750, 10.1210/endo-120-5-1750
Zawalich, 1985, Effect of exogenous phospholipase A2 on insulin secretion from perifused rat islets., Diabetes, 34, 471, 10.2337/diab.34.5.471
Turk, 1986, Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: quantitative effects on the phospholipid content of arachidonate and other fatty acids., Biochim Biophys Acta, 879, 399, 10.1016/0005-2760(86)90232-8
Konrad, 1992, Inhibition of phospholipase A2 and insulin secretion in pancreatic islets., Biochim Biophys Acta, 1135, 215, 10.1016/0167-4889(92)90139-3
Band, 1992, Arachidonic acid-induced insulin secretion from rat islets of Langerhans., J Mol Endocrinol, 8, 95, 10.1677/jme.0.0080095
Turk, 1992, Arachidonic acid metabolism in isolated pancreatic islets. VI. Carbohydrate insulin secretagogues must be metabolized to induce eicosanoid release., Biochim Biophys Acta, 1125, 280, 10.1016/0005-2760(92)90057-3
Gross, 1993, Rat and human pancreatic islet cells contain a calcium ion independent phospholipase A2 activity selective for hydrolysis of arachidonate which is stimulated by adenosine triphosphate and is specifically localized to islet β-cells., Biochemistry, 32, 327, 10.1021/bi00052a041
Ramanadham, 1993, Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in β-cell cytosolic calcium ion concentration., Biochemistry, 32, 337, 10.1021/bi00052a042
Loweth, 1996, A specific inhibitor of cytosolic phospholipase A2 activity, AACOCF3, inhibits glucose-induced insulin secretion from isolated rat islets., Biochem Biophys Res Commun, 218, 423, 10.1006/bbrc.1996.0075
Ma, 2001, Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2β) indicate a signaling rather than a housekeeping role for iPLA2β., J Biol Chem, 276, 13198, 10.1074/jbc.M010423200
Persaud, 2002, A key role for β-cell cytosolic phospholipase A2 in the maintenance of insulin stores but not in the initiation of insulin secretion., Diabetes, 51, 98, 10.2337/diabetes.51.1.98
Ma, 1998, Cloning and expression of a group IV cytosolic Ca2+-dependent phospholipase A2 from rat pancreatic islets. Comparison of the expressed activity with that of an islet group VI cytosolic Ca2+-independent phospholipase A2., Biochim Biophys Acta, 1391, 384, 10.1016/S0005-2760(98)00027-7
Jones, 2004, The role of cytosolic phospholipase A2 in insulin secretion., Diabetes, 53, S172, 10.2337/diabetes.53.2007.S172
Juhl, 2003, cPLA2α-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic β-cells., Am J Physiol Endocrinol Metab, 285, E73, 10.1152/ajpendo.00086.2003
Wolf, 1986, Intracellular Ca2+ mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets., J Biol Chem, 261, 3501, 10.1016/S0021-9258(17)35676-4
Wolf, 1991, Free fatty acid accumulation in secretagogue-stimulated pancreatic islets and effects of arachidonate on depolarization-induced insulin secretion., Biochemistry, 30, 6372, 10.1021/bi00240a004
Ramanadham, 1992, Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet β cells., Biochem Biophys Res Commun, 184, 647, 10.1016/0006-291X(92)90638-2
Ramanadham, 1994, ω-Conotoxin inhibits glucose- and arachidonic acid-induced rises in intracellular [Ca2+] in rat pancreatic islet β-cells., Cell Calcium, 15, 259, 10.1016/0143-4160(94)90065-5
Shuttleworth, 1996, Arachidonic acid activates the noncapacitative entry of Ca2+ during [Ca2+]i oscillations., J Biol Chem, 271, 21720, 10.1074/jbc.271.36.21720
Meglasson, 1986, Pancreatic islet glucose metabolism and regulation of insulin secretion., Diabetes Metab Rev, 2, 163, 10.1002/dmr.5610020301
Hazen, 1991, Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2., J Biol Chem, 266, 7227, 10.1016/S0021-9258(20)89634-3
Ackermann, 1995, Inhibition of macrophage Ca2+-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones., J Biol Chem, 270, 445, 10.1074/jbc.270.1.445
Balsinde, 1999, Regulation and inhibition of phospholipase A2., Annu Rev Pharmacol Toxicol, 39, 175, 10.1146/annurev.pharmtox.39.1.175
Ramanadham, 1993, Mass spectrometric characterization of arachidonate-containing plasmalogens in human pancreatic islets and in rat islet β-cells and subcellular membranes., Biochemistry, 32, 13499, 10.1021/bi00212a015
Ramanadham, 1993, Mass spectrometric identification and quantitation of arachidonate-containing phospholipids in pancreatic islets: prominence of plasmenylethanolamine molecular species., Biochemistry, 32, 5339, 10.1021/bi00071a009
Ramanadham, 1994, Characterization of an ATP-stimulatable Ca2+-independent phospholipase A2 from clonal insulin-secreting HIT cells and rat pancreatic islets: a possible molecular component of the β-cell fuel sensor., Biochemistry, 33, 7442, 10.1021/bi00189a052
Ma, 1997, Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin., J Biol Chem, 272, 11118, 10.1074/jbc.272.17.11118
Ma, 1999, Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A2 (iPLA2) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA2 gene on chromosome 22q13.1., J Biol Chem, 274, 9607, 10.1074/jbc.274.14.9607
Ma, 2001, Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2., Lipids, 36, 689, 10.1007/s11745-001-0774-9
Ma, 2002, Stimulation of insulin secretion and associated nuclear accumulation of iPLA2β in INS-1 insulinoma cells., Am J Physiol Endocrinol Metab, 282, E820, 10.1152/ajpendo.00165.2001
Ramanadham, 1999, Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells., J Biol Chem, 274, 13915, 10.1074/jbc.274.20.13915
Balsinde, 1996, Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohy-drolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages., J Biol Chem, 271, 31937, 10.1074/jbc.271.50.31937
Balboa, 1998, Involvement of phosphatidate phosphohydrolase in arachidonic acid mobilization in human amnionic WISH cells., J Biol Chem, 273, 7684, 10.1074/jbc.273.13.7684
Hsu, 2000, Electrospray ionization/mass spectrometric analyses of human promonocytic U937 cell glycerolipids and evidence that differentiation is associated with membrane lipid composition changes that facilitate phospholipase A2 activation., J Biol Chem, 275, 16579, 10.1074/jbc.M908342199
Abdel-Latif, 1984, Studies on the effects of magnesium ion and propranolol on iris muscle phosphatidate phosphohydrolase., Can J Biochem Cell Biol, 62, 170, 10.1139/o84-024
Pappu, 1983, Propranolol-induced inhibition of rat brain cytoplasmic phosphatidate phosphohydrolase., Neurochem Res, 8, 1565, 10.1007/BF00964158
Meier, 1998, Effects of propranolol on phosphatidate phosphohydrolase and mitogen-activated protein kinase activities in A7r5 vascular smooth muscle cells., Cell Signal, 10, 415, 10.1016/S0898-6568(97)00140-X
Johnson, 1999, Regulation of cyclooxygenase-2 expression by phosphatidate phosphohydrolase in human amnionic WISH cells., J Biol Chem, 274, 27689, 10.1074/jbc.274.39.27689
Rossetti, 1997, Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele., Am J Physiol Endocrinol Metab, 273, E743, 10.1152/ajpendo.1997.273.4.E743
Niswender, 1997, Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism., J Biol Chem, 272, 22570, 10.1074/jbc.272.36.22570
Niswender, 1997, Cell-specific expression and regulation of a glucokinase gene locus transgene., J Biol Chem, 272, 22564, 10.1074/jbc.272.36.22564
Metz, 1988, Exogenous arachidonic acid promotes insulin release from intact or permeabilized rat islets by dual mechanisms. Putative activation of Ca2+ mobilization and protein kinase C., Diabetes, 37, 1453, 10.2337/diab.37.11.1453
Landt, 1992, Parallel effects of arachidonic acid on insulin secretion, calmodulin-dependent protein kinase activity and protein kinase C activity in pancreatic islets., Cell Calcium, 13, 163, 10.1016/0143-4160(92)90044-S
Band, 1993, The mechanism of arachidonic acid-induced insulin secretion from rat islets of Langerhans., Biochim Biophys Acta, 1176, 64, 10.1016/0167-4889(93)90178-R
Ramanadham, 2000, Electrospray ionization mass spectrometric analyses of phospholipids from INS-1 insulinoma cells: comparison to pancreatic islets and effects of fatty acid supplementation on phospholipid composition and insulin secretion., Biochim Biophys Acta, 1484, 251, 10.1016/S1388-1981(00)00022-6
Hanks, 1988, The protein kinase family: conserved features and deduced phylogeny of the catalytic domains., Science, 241, 42, 10.1126/science.3291115
Wolf, 1996, Expression, purification, and kinetic characterization of a recombinant 80-kDa intracellular calcium-independent phospholipase A2., J Biol Chem, 271, 30879, 10.1074/jbc.271.48.30879
Smani, 2004, A novel mechanism for the store-operated calcium influx pathway., Nat Cell Biol, 6, 113, 10.1038/ncb1089
Smani, 2003, Ca2+-independent phospholipase A2 is a novel determinant of store-operated Ca2+ entry., J Biol Chem, 278, 11909, 10.1074/jbc.M210878200
Lacy, 1967, Method for the isolation of intact islets of Langerhans from the rat pancreas., Diabetes, 16, 35, 10.2337/diab.16.1.35
Ferrara, 1985, Effects of β-receptor blockade on carbohydrate metabolism., J Hypertens, 3, S199