Infrared tissue imaging at on-the-spot laser delivery using an all-optical-waveguide transmitting system

I.K. Ilev1, R.W. Waynant2
1US Food and Drug Administration, Center for Devices and Radiological Health, Rockville, MD
2US Food and Drug Administration, Center for Devices and Radiological Health, Rockville, MD, USA

Tóm tắt

We present experimental results on mid-infrared thermal imaging of micro-scale tissue area irradiated by an all-optical-waveguide laser delivery system. The infrared transmitting system is based on a novel and simple laser delivery technique that includes two key optical elements: a grazing-incidence-based uncoated hollow taper used for direct infrared laser-to-fiber coupling, and a tissue-activated optical fiber probe with a specially shaped tip. The lens-free all-optical-waveguide transmitting system provides on-the-spot laser delivery into a precise micro-scale tissue area. When an Er:YAG (/spl lambda/=2.94 /spl mu/m) laser is used as a mid-infrared laser source, we obtain infrared thermal images from a small-size tissue area and a single hair.

Từ khóa

#Infrared imaging #Optical imaging #Free electron lasers #Fiber lasers #Laser modes #Biomedical optical imaging #Optical coupling #Optical sensors #Optical fibers #Laser theory

Tài liệu tham khảo

10.1063/1.1150042 10.1063/1.123966 10.1364/AO.39.003192 10.1109/3.853551 ilev, 2001, Evanescent wave delivery to a precise tissue area using fiber-optic tips, Attenuation measurement of infrared optical fibers using a hollow-taper-based coupling method SPIE, 4253, 161 holst, 2001, Infrared Imaging Systems: Design, Analysis, Modeling and Testing, Proc SPIE, 4372 sanghera, 1998, Infrared Fiber Optics