Influence of L-citrulline and watermelon supplementation on vascular function and exercise performance

Current Opinion in Clinical Nutrition and Metabolic Care - Tập 20 Số 1 - Trang 92-98 - 2017
Arturo Figueroa1,2,3, Alexei Wong, Salvador J. Jaime, Joaquin U. Gonzales
1e-mail: [email protected]
2fax: +1 850 645 5000
3to Dr Arturo Figueroa, MD, PhD, Department of Nutrition, Food, and Exercise Sciences, Florida State University, Tallahassee, FL 32306, USA. Tel: +1 850 644 8089

Tóm tắt

Từ khóa


Tài liệu tham khảo

Gamboa, 2016, Autonomic blockade reverses endothelial dysfunction in obesity-associated hypertension, Hypertension, 68, 1004, 10.1161/HYPERTENSIONAHA.116.07681

Vanhoutte, 2016, Thirty years of saying NO – sources, fate, actions, and misfortunes of the endothelium-derived mediator, Circ Res, 119, 375, 10.1161/CIRCRESAHA.116.306531

Wijnands, 2015, Citrulline supplementation improves organ perfusion and arginine availability under conditions with enhanced arginase activity, Nutrients, 7, 5217, 10.3390/nu7075217

Zhao, 2015, Vascular nitric oxide: beyond eNOS, J Pharmacol Sci, 129, 83, 10.1016/j.jphs.2015.09.002

Moinard, 2016, Arginine behaviour after arginine or citrulline administration in older subjects, Br J Nutr, 115, 399, 10.1017/S0007114515004638

Bailey, 2016, Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans, Nitric Oxide, 59, 10, 10.1016/j.niox.2016.06.008

McKinley-Barnard, 2015, Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis, J Int Soc Sports Nutr, 12, 27, 10.1186/s12970-015-0086-7

Schwedhelm, 2008, Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism, Br J Clin Pharmacol, 65, 51, 10.1111/j.1365-2125.2007.02990.x

Breuillard, 2015, Citrulline and nitrogen homeostasis: an overview, Amino Acids, 47, 685, 10.1007/s00726-015-1932-2

Shanely, 2016, Comparison of watermelon and carbohydrate beverage on exercise-induced alterations in systemic inflammation, immune dysfunction, and plasma antioxidant capacity, Nutrients, 8, 518, 10.3390/nu8080518

Morita, 2014, Oral supplementation with a combination of L-citrulline and L-arginine rapidly increases plasma L-arginine concentration and enhances NO bioavailability, Biochem Biophys Res Commun, 454, 53, 10.1016/j.bbrc.2014.10.029

Bailey, 2015, L-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans, J Appl Physiol (1985, 119, 385, 10.1152/japplphysiol.00192.2014

Kövamees, 2016, Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus, J Clin Endocrinol Metab, 126, 2943

Kim, 2015, Acute ingestion of citrulline stimulates nitric oxide synthesis in young and older subjects, Am J Physiol Endocrinol Metab, 309, E915, 10.1152/ajpendo.00339.2015

Churchward-Venne, 2014, Citrulline does not enhance blood flow, microvascular circulation, or myofibrillar protein synthesis in elderly men at rest or following exercise, Am J Physiol Endocrinol Metab, 307, E71, 10.1152/ajpendo.00096.2014

Kobayashi, 2015, Arterial stiffness after glucose ingestion in exercise-trained versus untrained men, Appl Physiol Nutr Metab, 40, 1151, 10.1139/apnm-2015-0131

Ochiai, 2012, Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men, Int J Cardiol, 155, 257, 10.1016/j.ijcard.2010.10.004

Wong, 2016, Combined whole-body vibration training and L-citrulline supplementation improves pressure wave reflection in obese postmenopausal women, Appl Physiol Nutr Metab, 41, 292, 10.1139/apnm-2015-0465

Morita, 2013, Effects of oral L-citrulline supplementation on lipoprotein oxidation and endothelial dysfunction in humans with vasospastic angina, Immunol Endocr Metab Agents Med Chem, 13, 214, 10.2174/18715222113139990008

Orozco-Gutierrez, 2010, Effect of L-arginine or L-citrulline oral supplementation on blood pressure and right ventricular function in heart failure patients with preserved ejection fraction, Cardiol J, 17, 612

Alsop, 2016, Oral nitrate and citrulline decrease blood pressure and increase vascular conductance in young adults: a potential therapy for heart failure, Eur J Appl Physiol, 116, 1651, 10.1007/s00421-016-3418-7

Figueroa, 2016, L-Citrulline supplementation attenuates blood pressure, wave reflection and arterial stiffness responses to metaboreflex and cold stress in overweight men, Br J Nutr, 116, 279, 10.1017/S0007114516001811

Figueroa, 2010, Oral L-citrulline supplementation attenuates blood pressure response to cold pressor test in young men, Am J Hypertens, 23, 12, 10.1038/ajh.2009.195

Figueroa, 2012, Watermelon extract supplementation reduces ankle blood pressure and carotid augmentation index in obese adults with prehypertension or hypertension, Am J Hypertens, 25, 640, 10.1038/ajh.2012.20

Figueroa, 2013, Effects of watermelon supplementation on arterial stiffness and wave reflection amplitude in postmenopausal women, Menopause, 20, 573, 10.1097/gme.0b013e3182733794

Figueroa, 2014, Effects of watermelon supplementation on aortic hemodynamic responses to the cold pressor test in obese hypertensive adults, Am J Hypertens, 27, 899, 10.1093/ajh/hpt295

Massa, 2016, Watermelon extract reduces blood pressure but does not change sympathovagal balance in prehypertensive and hypertensive subjects, Blood Press, 25, 244, 10.3109/08037051.2016.1150561

Ubolsakka-Jones, 2016, Older women with controlled isolated systolic hypertension: exercise and blood pressure, Med Sci Sports Exerc, 48, 983, 10.1249/MSS.0000000000000883

Sanchez-Gonzalez, 2013, The effects of short term L-citrulline supplementation on wave reflection responses to cold exposure with concurrent isometric exercise, Am J Hypertens, 26, 518, 10.1093/ajh/hps052

Figueroa, 2015, Impact of L-citrulline supplementation and whole-body vibration training on arterial stiffness and leg muscle function in obese postmenopausal women with high blood pressure, Exp Gerontol, 63, 35, 10.1016/j.exger.2015.01.046

Bendahan, 2002, Citrulline/malate promotes aerobic energy production in human exercising muscle, Br J Sports Med, 36, 282, 10.1136/bjsm.36.4.282

Cutrufello, 2015, The effect of L-citrulline and watermelon juice supplementation on anaerobic and aerobic exercise performance, J Sports Sci, 33, 1459, 10.1080/02640414.2014.990495

Tarazona-Díaz, 2013, Watermelon juice: potential functional drink for sore muscle relief in athletes, J Agric Food Chem, 61, 7522, 10.1021/jf400964r

Suzuki, 2016, Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: double-blind randomized placebo-controlled 2-way crossover study, J Int Soc Sports Nutr, 13, 6, 10.1186/s12970-016-0117-z

Takeda, 2011, Effects of citrulline supplementation on fatigue and exercise performance in mice, J Nutr Sci Vitaminol (Tokyo, 57, 246, 10.3177/jnsv.57.246

Devries, 2015, Low-load resistance training during step-reduction attenuates declines in muscle mass and strength and enhances anabolic sensitivity in older men, Physiol Rep, 3, e12493, 10.14814/phy2.12493