In vitro antioxidant activity and bioactive compounds from Calocybe indica

Hue University Journal of Science: Natural Science - Tập 130 Số 1D - Trang 15-22 - 2021
Quang Man Nguyen1, Lam Son Le2, Minh Nhung Nguyen3, Chinh Chien Nguyen4, Xuan Anh Vu Ho2, Vinh Phu Nguyen1, Thanh Minh Tran2, Thuy Trang Le2, Thi Van Thi Tran2, Le Trung Hieu2
1University of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Viet Nam
2University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam
3Technical Centre for Quality Measurement Standards, Department of Science and Technology of Thua Thien Hue, Vy Da 7 Planning Area, Vy Da, Hue, Viet Nam
4Laboratory of Energy and Environmental Science, Institute of Research and Development, Duy Tan University, Da Nang, Vietnam 5Faculty of Environmental and Chemical Engineering, Duy Tan University, Da Nang, Vietnam

Tóm tắt

Nowadays, the use of mushrooms in medicine is ubiquitous and has achieved particular success. The antioxidants in mushrooms can deactivate free radicals. This study assesses the antioxidant potential of mushroom Calocybe indica with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging methods and the total antioxidant capacity. The mushroom’s ethanol extract exhibits acceptable activity with a low IC50 value (240.11 μg/mL), approximately 2.9 times lower than that of the mushroom Ophiocordyceps sobolifera extract. The ABTS scavenging rate of the extract is around 60% at 500 µg/mL, and the total antioxidant capacity is equivalent to 64.94 ± 1.03 mg of GA/g or 77.42 ± 0.42 μmol of AS/g.  The total phenolics, flavonoids, polysaccharides, and triterpenoids are equivalent to 29.33 ± 0.16 mg of GAE/g, 17.84 ± 0.11 mg of QUE/g (5.04 ± 0.04%), and 4.96 ± 0.04 mg of oleanolic acid/g, respectively. Specifically, the total triterpenoid content has been reported for the first time. The mushroom can have potential biomedical applications.

Từ khóa

#Calocybe indica #antioxidant activity #polysaccharide #triterpenoid #total phenolics #total flavonoid

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Hue University Journal of Science: Natural Science

Tập 130 Số 1D

15-22

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