Impulsive-aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide

Psychological Medicine - Tập 38 Số 3 - Trang 407-417 - 2008
Alexander McGirr1, Johanne Renaud1, Alexandre Bureau2, Monique Séguin1, Alain Lesage3,1, Gustavo Turecki1
1McGill Group for Suicide Studies, Douglas Hospital Research Center, McGill University, Montreal, Canada
2Department of Social and Preventive Medicine, Université Laval, Quebec City, Canada
3Department of Psychiatry, University of Montreal, Montreal, Canada

Tóm tắt

BackgroundIt is unclear whether the association between impulsive-aggressive behaviours and suicide exists across different ages.MethodVia psychological autopsy, we examined a total of 645 subjects aged 11–87 years who died by suicide. Proxy-based interviews were conducted using the SCID-I & SCID-II or K-SADS interviews and a series of behavioural and personality-trait assessments. Secondarily, 246 living controls were similarly assessed.ResultsHigher levels of impulsivity, lifetime history of aggression, and novelty seeking were associated with younger age of death by suicide, while increasing levels of harm avoidance were associated with increasing age of suicide. This effect was observed after accounting for age-related psychopathology (current and lifetime depressive disorders, lifetime anxiety disorders, current and lifetime substance abuse disorders, psychotic disorders and cluster B personality disorders). Age effects were not due to the characteristics of informants, and such effects were not observed among living controls. When directly controlling for major psychopathology, the interaction between age, levels of impulsivity, aggression and novelty seeking predicted suicide status while controlling for the independent contributions of age and these traits.ConclusionsHigher levels of impulsive-aggressive traits play a greater role in suicide occurring among younger individuals, with decreasing importance with increasing age.

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