Immunoreactive atrial natriuretic peptide (ANP) in endoscopic biopsies of the human gastrointestinal tract

Research in Experimental Medicine - Tập 189 - Trang 421-425 - 1989
H. Ehrenreich1, F. Sinowatz2, R. Schulz3, R. M. Arendt4, F. -D. Goebel5
1Klinikum Großhadern, Neurologische Universitätsklinik, München, FRG
2Institut für Tieranatomie II, Universität München, München, FRG
3Institut für Pharmakologie, Toxikologie und Pharmazie der Universität München, München, FRG
4Medizinische Klinik I, Klinikum Großhadern, Universität München, München, FRG
5Medizinische Poliklinik, Universität München, München, 2, FRG

Tóm tắt

The human gastrointestinal tract, important for body salt and water balance, was investigated by endoscopic biopsy for the presence of atrial natriuretic peptide (ANP). Using immunohistochemistry, ANP-immunoreactive cells were identified in the lamina epithelialis mucosae of stomach, duodenum, jejunum, colon, and rectum. The findings indicate that ANP plays a role in intestinal salt and water regulation in man. ANP measurements in tissue specimens reached by endoscopic biopsy may be of major interest for future investigations on (patho-)physiological and pharmacological aspects of ANP.

Tài liệu tham khảo

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