Immunopathogenic mechanisms in psoriasis

Espinoza, 1992, Psoriatic arthritis, Curr Opin Rheumatol, 4, 470

Brandrup, 1982, Psoriasis in monozygotic twins: variations in expression in individuals with identical constitution, Acta Derma Venereol, 62, 229, 10.2340/0001555562229236

Veal, 2002, Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus, Am J Hum Genet, 71, 554, 10.1086/342289

Gudjonsson, 2002, HLA-Cw6-Positive and HLA-Cw6-Negative Patients with Psoriasis Vulgaris have Distinct Clinical Features, J Invest Dermatol, 118, 362, 10.1046/j.0022-202x.2001.01656.x

Enerback, 1997, Evidence that HLA-Cw6 determines early onset of psoriasis, obtained using sequence-specific primers (PCR-SSP), Acta Derm Venereol, 77, 273, 10.2340/0001555577273276

Gudjonsson, 2003, Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2.5 fold increased risk of developing psoriasis compared with Cw6 heterozygotes, Br J Dermatol, 148, 233, 10.1046/j.1365-2133.2003.05115.x

Valdimarsson, 1986, Psoriasis: a disease of abnormal proliferation induced by T lymphocytes, Immunol Today, 7, 256, 10.1016/0167-5699(86)90005-8

Austin, 1998, Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17 (TIA-1) +CD8+CD3+ CTLs as determined by phenotypic analysis, J Cutan Pathol, 25, 79, 10.1111/j.1600-0560.1998.tb01694.x

Paukkonen, 1992, The development of manifest psoriatic lesions is linked with the invasion of CD8+ T cells and CD11c + macrophages into the epidermis, Arch Dermatol Res, 284, 375, 10.1007/BF00372065

Gelfant, 1982, On the existence of non-cycling germinative cells in human epidermis in vivo and cell cycle aspects of psoriasis, Cell Tissue Kinet, 15, 393

Weinstein, 1985, Cell kinetic basis for pathophysiology of psoriasis, J Invest Dermatol, 85, 579, 10.1111/1523-1747.ep12283594

Leigh, 1985, Psoriasis. maintenance of an intact monolayer basal cell differentiation compartment in spite of hyperproliferaiton, Br J Dermatol, 113, 53, 10.1111/j.1365-2133.1985.tb02044.x

Leigh, 1995, Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro, Br J Dermatol, 133, 501, 10.1111/j.1365-2133.1995.tb02696.x

Fry, 1988, Dermatol, 119, 445

Telfer, 1994, The role of streptococcal infection in the initiation of guttate psoriasis, Arch Dermatol, 128, 39, 10.1001/archderm.1992.01680110049004

Gudjonsson, 2003, Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a propestive study, Br J Dermatol, 149, 530, 10.1046/j.1365-2133.2003.05552.x

Mallon, 2000, HLA-C and guttate psoriasis, Br J Dermatol, 143, 1177, 10.1046/j.1365-2133.2000.03885.x

Leung, 1995, Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associatied antigen, via stimulation of interleukin 12 production, J Exp Med, 181, 747, 10.1084/jem.181.2.747

Sigmundsdottir, 2003, Interleukin-12 alone can not enhance the expression of the cutaneous lymphocyte antigen (CLA) by superantigen stimulated T lymphocytes, Clin Exp Immunol, 132, 430, 10.1046/j.1365-2249.2003.02169.x

LaPenta, 1994, Group A streptococci efficiently invade human respiratory epithelial cells, Proc Natl Acad Scie USA, 91, 12115, 10.1073/pnas.91.25.12115

Dombek, 1999, High-frequency intracellular invasion of epithelial cells by serotype M1 group A streptococci: M1 protein-mediated invasion and cytoskeletal rearrangements, Mol Microbiol, 31, 859, 10.1046/j.1365-2958.1999.01223.x

Osterlund, 1997, Intracellular reservoir of Streptococcus pyogenes in vivo: a possible explanation for recurrent pharyngotonsillitis, Laryngoscope, 107, 640, 10.1097/00005537-199705000-00016

Ovigne, 2002, Epidermal CD8+ T cells reactive with group A streptococcal antigens in chronic plaque psoriasis, Exp Dermatol, 11, 357, 10.1034/j.1600-0625.2002.110410.x

Brown, 2000, Skin CD4+ T cells produce interferon-gamma in vitro in response to streptococcal antigens in chronic plaque psoriasis, J Invest Dermatol, 114, 576, 10.1046/j.1523-1747.2000.00919.x

Ellis, 2001, Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes, N Engl J Med, 345, 248, 10.1056/NEJM200107263450403

McMillin, 1999, A role for tonsillectomy in the treatment of psoriasis?, Ear Nose Throat J, 78, 155, 10.1177/014556139907800308

Takahara, 2001, Efficacy of tonsillectomy on psoriasis and tonsil histology, Nippon Jibiinkoka Gakkai Kaiho, 104, 1065, 10.3950/jibiinkoka.104.1065

Perry, 1998, Immunology of the tonsils, Immunol Today, 19, 414, 10.1016/S0167-5699(98)01307-3

Mueller, 1979, Cyclosporin A for psoriasis, N Engl J Med, 301, 555, 10.1056/NEJM197909063011015

Bos, 1983, Immunocompetent cells in psoriasis. In site immunophenotyping by monoclonal antibodies, Arch Dermatol Res, 275, 181, 10.1007/BF00510050

Baker, 1984, Epidermal T lymphocytes and HLA-DR expression in psoriasis, Br J Dermatol, 110, 555, 10.1111/j.1365-2133.1984.tb04678.x

Baker, 1985, Epidermal T lymphocytes and dendritic cells in chronic plaque psoriasis: the effects of PUVA treatment, Clin Exp Immunol, 61, 536

Ellis, 1986, Cyclosporine improves psoriasis in a double-blind study, J Am Med Assoc, 256, 3110, 10.1001/jama.1986.03380220076026

Griffiths, 1986, Clearance of psoriasis with low dose cyclosporin, Br Med J, 293, 731, 10.1136/bmj.293.6549.731

Morel, 1992, Anti-CD4 monoclonal antibody therapy in severe psoriasis, J Autoimmun, 5, 465, 10.1016/0896-8411(92)90006-C

Gottlieb, 1995, Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis, Nat Med, 1, 442, 10.1038/nm0595-442

Wrone-Smith, 1996, Dermal injection of immunocytes induces psoriasis, J Clin Invest, 98, 1878, 10.1172/JCI118989

Nickoloff, 1999, Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis, Am J Pathol, 155, 145, 10.1016/S0002-9440(10)65109-7

Kieper, 2002, Overexpression of interleukin (IL) -7 leads to IL-15-independent generation of memory phenotype CD8+ T cells, J Exp Med, 195, 1533, 10.1084/jem.20020067

Tan, 2002, Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells, J Exp Med, 195, 1523, 10.1084/jem.20020066

Gröne, 2002, Keratinocytes and cytokines, Vet Immunol Immunopathol, 88, 1, 10.1016/S0165-2427(02)00136-8

Yawalkar, 1998, Expression of interleukin-12 is increased in psoriatic skin, J Invest Dermatol, 111, 1053, 10.1046/j.1523-1747.1998.00446.x

Gearing, 1990, Cytokines in skin lesions of psoriasis, Cytokine, 2, 68, 10.1016/1043-4666(90)90045-U

Fierlbeck, 1990, Psoriasis induced at the injection site of recombinant interferon gamma. Results of immunohistologic investigations, Arch Dermatol, 126, 351, 10.1001/archderm.1990.01670270083013

Tominaga, 2000, IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells, Int Immunol, 12, 151, 10.1093/intimm/12.2.151

Teunissen, 1998, Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes, J Invest Dermatol, 111, 645, 10.1046/j.1523-1747.1998.00347.x

Turbitt, 1990, Localization of elevated transforming growth factor-alpha in psoriatic epidermis, J Invest Dermatol, 95, 229, 10.1111/1523-1747.ep12478077

Blumberg, 2001, Interleukin 20. Discovery, receptor identification, and role in epidermal function, Cell, 104, 9, 10.1016/S0092-8674(01)00187-8

Prinz, 1994, T cell clones from psoriasis skin lesions can promote keratinocyte proliferation in vitro via secreted products, Eur J Immunol, 24, 593, 10.1002/eji.1830240315

Quin, 1999, Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes, J Biol Chem, 274, 37957, 10.1074/jbc.274.53.37957

Ruckert, 2000, Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis?, J Immunol, 165, 2240, 10.4049/jimmunol.165.4.2240

Schopf, 2002, Treatment of psoriasis with the chimeric monoclonal antibody against tumor necrosis factor alpha, infliximab, J Am Acad Dermatol, 46, 886, 10.1067/mjd.2002.120472

Schon, 2001, Psoriasis: the plot thickens…, Nat Immunol, 2, 91, 10.1038/84293

Lin, 2001, Oligoclonal expansion of intraepidermal T cells in psoriasis skin lesions, J Invest Dermatol, 117, 1546, 10.1046/j.0022-202x.2001.01548.x

Vollmer, 2001, Dominant lesional T cell receptor rearrangements persist in relapsing psoriasis but are absent from nonlesional skin: Evidence for a stable antigen-specific pathogenic T cell response in psoriasis vulgaris, J Invest Dermatol, 117, 1296, 10.1046/j.0022-202x.2001.01494.x

Wardrop, 1998, Tonsillitis and chronic psoriasis, Clin Otolaryngol, 23, 67, 10.1046/j.1365-2273.1998.00084.x

Valdimarsson, 1995, Psoriasis: a T cell-mediated autoimmune disease induced by streptococcal superantigens?, Immunol Today, 16, 145, 10.1016/0167-5699(95)80132-4

McFadden, 1991, Cross-reactivity between streptococcal M surface antigen and human skin, Br J Dermatol, 125, 443, 10.1111/j.1365-2133.1991.tb14769.x

Gudmundsdottir, 1999, Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?, Clin Exp Immunol, 117, 580, 10.1046/j.1365-2249.1999.01013.x

Sigmundsdottir, 1997, Circulating T cells of patients with active psoriasis respond to streptococcal M-peptides sharing sequences with human epidermal keratins, Scand J Immunol, 45, 688, 10.1046/j.1365-3083.1997.d01-438.x

McGowan, 1998, The wound repair-associated keratins 6, 16, and 17. Insights into the role of intermediate filaments in specifying keratinocyte cytoarchitecture, Subcell Biochem, 31, 173

Fry, 1992, An atlas of psoriasis, 10.3109/9780203640401

Onuma, 1994, Immunohistochemical studies of infiltrating cells in early and chronic lesions of psoriasis, J Dermatol, 21, 223, 10.1111/j.1346-8138.1994.tb01727.x

Chang, 1994, CD8+ T cells in psoriatic lesions preferentially use T cell receptor V beta 3 and/or V beta 13.1 genes, Proc Natl Acad Sci USA, 91, 9282, 10.1073/pnas.91.20.9282

Nickoloff, 1999, The Immunologic and genetic basis of psoriasis, Arch Dermatol, 135, 1104, 10.1001/archderm.135.9.1104

Wrone-Smith, 1997, Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin, Am J Pathol, 151, 1321

Aractingi, 2001, HLA-G and NK receptor are expressed in psoriatic skin: a possibly pathway for regulating infiltrating T cells?, Am J Pathol, 159, 71, 10.1016/S0002-9440(10)61675-6

Krueger, 1995, Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells, J Exp Med, 182, 2057, 10.1084/jem.182.6.2057

Rattis, 1998, Effects of ultraviolet B radiation on human Langerhans cells: functional alteration of CD86 upregulation and induction of apoptotic cell death, J Invest Dermatol, 111, 373, 10.1046/j.1523-1747.1998.00320.x

Merad, 2002, Langerhans cells renew in the skin throughout life under steady-state conditions, Nat Immunol, 4, 1135, 10.1038/ni852

Myskowski, 1996, Dermatologic complications of HIV infection, Med Clin North Am, 80, 1415, 10.1016/S0025-7125(05)70496-X

Fischer, 1999, Clinical improvement of HIV-associated psoriasis parallels a reduction of HIV viral load induced by effective antiretroviral therapy, AIDS, 13, 628, 10.1097/00002030-199904010-00018

Kursar, 2002, Regulatory CD4+CD25+T cells restrict memory CD8+ T cell responses, J Exp Med, 196, 1585, 10.1084/jem.20011347

Ribeiro, 2002, In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted?, Proc Natl Acad Sci USA, 99, 15572, 10.1073/pnas.242358099

Obuch, 1992, Psoriasis and human immunodeficiency virus infection, J Am Acad Dermatol, 27, 667, 10.1016/0190-9622(92)70234-7

Colebunders, 1992, Psoriasis regression in terminal AIDS, Lancet, 339, 1110, 10.1016/0140-6736(92)90701-4

Falk, 1997, revisited. Ten years of change, Immunol Res, 16, 203, 10.1007/BF02786363

Malissen, 1981, Clones of human cytotoxic T lymphocytes derived from an allosensitized individual: HLA specificity and cell surface markers, Scand J Immunol, 14, 213, 10.1111/j.1365-3083.1981.tb00558.x

Schendel, 1992, Cytotoxic T lymphocytes show HLA-C-restricted recognition of EBV-bearing cells and allorecognition of HLA class I molecules presenting self-peptides, J Immunol, 149, 2406, 10.4049/jimmunol.149.7.2406

Van Der Bruggen, 1994, Autologous cytolytic T lymphocyte recognize a MAGE-1 nonapeptide on melanomas expressing HLA-Cw*1601, Eur J Immunol, 24, 2134, 10.1002/eji.1830240930

Jenisch, 1998, Linkage analysis of human leukocyte antigen (HLA) markers in familial psoriasis: a strong disequilibrium effects provide evidence for a major determinant in the HLA-B/-C region, Am J Hum Genet, 63, 191, 10.1086/301899

Hugot, 2001, Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease, Nature, 411, 599, 10.1038/35079107

Ogura, 2001, A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease, Nature, 411, 603, 10.1038/35079114

Maillard, 2002, Complementary dendritic cell-activating function of CD8+ and CD4+ T cells: helper role of CD8+ T cells in the development of T helper type 1 responses, J Exp Med, 195, 473, 10.1084/jem.20011662

Abrarms, 2000, Blockade of T lymphocyte costimulatin with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells, and endothelial cells, J Exp Med, 192, 681, 10.1084/jem.192.5.681

Bevan, 1976, Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay, J Exp Med, 143, 1283, 10.1084/jem.143.5.1283

Heath, 2001, Cross-presentation, dendritic cells, tolerance and immunity, Annu Rev Immunol, 19, 47, 10.1146/annurev.immunol.19.1.47

Kurts, 1996, Constitutive class I-restricted exogenous presentation of self antigens in vivo, J Exp Med, 184, 923, 10.1084/jem.184.3.923

Skoberne, 2002, Cross-presentation of Listeria monocytogenes-derived CD4 T cell epitopes, J Immunol, 169, 1410, 10.4049/jimmunol.169.3.1410

Den Haan, 2001, Antigen presentation to CD8+ T cells: cross-priming in infectious diseases, Curr Opin Immunol, 13, 437, 10.1016/S0952-7915(00)00238-7

Bennett, 1998, Help for cytotoxic-T cell responses is mediated by CD40 signalling, Nature, 393, 478, 10.1038/30996

Larsson, 2001, Efficiency of cross presentation of vaccinia virus-derived antigens by human dendritic cells, Eur J Immunol, 31, 3432, 10.1002/1521-4141(200112)31:12<3432::AID-IMMU3432>3.0.CO;2-R

Harshyne, 2001, Dendritic cells acquire antigens from live cells for cross-presentation to CTL, J Immunol, 166, 3717, 10.4049/jimmunol.166.6.3717

Ramirez, 2002, Macrophages and dendritic cells use the cytosolic pathway to rapidly cross-present antigen from live, vaccinia-infected cells, J Immunol, 169, 6733, 10.4049/jimmunol.169.12.6733

Carbone, 1998, Cross-presentation. a general mechanism for CTL immunity and tolerance, Immunol Today, 19, 368, 10.1016/S0167-5699(98)01301-2

De Mare, 1990, Flow cytometric quantification of human epidermal cells expressing keratin 16 in vivo after standardized trauma, Arch Dermatol Res, 282, 126, 10.1007/BF00493471

Wei, 1999, IL-1 beta and IFN-gamma induce the phenotype of psoriasis in the transwell skin organ culture system. IFN-gamma upregulates the expression of keratin 17 and keratinocyte transglutaminase via endogenous IL-1 production, J Pathol, 187, 358, 10.1002/(SICI)1096-9896(199902)187:3<358::AID-PATH253>3.0.CO;2-8

Roep, 2002, Autoreactive T cells in endocrine/organ-specific autoimmunity: why has progress been so slow?, Springer Semin Immunopathol, 24, 261, 10.1007/s00281-002-0109-8

Wucherpfennig, 2001, Mechanisms for the induction of autoimmunity by infectious agents, J Clin Invest, 108, 1097, 10.1172/JCI200114235

Ronchetti, 1999, Role of antigen-presenting cells in cross-priming of cytotoxic T lymphocytes by apoptotic cells, J Leukoc Biol, 66, 247, 10.1002/jlb.66.2.247

Serbina, 2001, CD4 (+) T cells are required for the development of cytotoxic CD8 (+) T cells during Mycobacterium tuberculosis infection, J Immunol, 167, 6991, 10.4049/jimmunol.167.12.6991

Schrijver, 2001, Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis, Brain, 124, 1544, 10.1093/brain/124.8.1544

Filaci, 2002, CD8+ T suppressor cells are back to the game: are they players in autoimmunity, Autoimmunity Rev, 1, 279, 10.1016/S1568-9972(02)00065-4