Immunological mechanisms of the antitumor effects of supplemental oxygenation

American Association for the Advancement of Science (AAAS) - Tập 7 Số 277 - 2015
Stephen Hatfield1, Jørgen Kjærgaard1, Dmitriy Lukashev1, Taylor H. Schreiber2, Bryan Belikoff1, Robert Abbott1, Shalini Sethumadhavan1, Phaethon Philbrook1, Kami Ko1, Ryan Cannici1, Molly Thayer1, Scott J. Rodig3, Jeffrey L. Kutok3, Edwin K. Jackson4, Barry L. Karger5, Eckhard R. Podack2, Akio Ohta1, Michail V. Sitkovsky6,1
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA,
2Department of Microbiology and Immunology, University of Miami, Miller School of Medicine, Miami, FL 33136, USA
3Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 20 Shattuck Street, Boston, MA 02115 USA
4Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
5Barnett Institute of Chemical and Biological Analysis, Northeastern University, Boston, MA 02115, USA
6Cancer Vaccine Center, Dana-Farber Cancer Institute, Harvard Institutes of Medicine, 44 Binney Street, Boston, MA 02115, USA.

Tóm tắt

Respiratory hyperoxia stimulates lung tumor regression by promoting T cell infiltration into the tumors and decreasing immunosuppression.

Từ khóa


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American Association for the Advancement of Science (AAAS)

Tập 7 Số 277

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