Imaging findings of extraosseous multiple myeloma
Cancer Imaging - 2015
Tóm tắt
Multiple myeloma is characterised by a progressive proliferation of malignant plasma cells usually initiating in the bone marrow. The most common manifestations of this disease are bone involvement, renal disease and hematologic disorders. The radiological findings of diffuse osteopenia or osteolytic bone lesions are well recognised. Extraosseous myelomatous masses are found in less than 5% of multiple myeloma patients. The purpose of this essay is to acquaint the radiologist with this phenomenon and to illustrate the imaging features of the extraosseous masses of this unusual manifestation of multiple myeloma.
Từ khóa
Tài liệu tham khảo
Innes J, Newall J. Myelomatosis. Lancet 1961; 1: 239–45.
Basset WB, Weiss RB. Plasmacytoma of the breast: an unusual manifestation of multiple myeloma. South Med J 1970; 72: 1492–4.
Wiltshaw E. The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine 1976; 55: 217–38.
Bloomberg TJ, Glees JP, Williams GE. Bilateral breast lumps: an unusual feature of extramedullary plasmacytoma. Br J Radiol 1980; 53: 498–501.
Moulopoulos LA, Granfield CAJ, Dimopoulos MA, Kim EE, Alexanian R, Libshiz HI. Extraosseous multiple myeloma: imaging features. AJR 1993; 161: 1083–7.
Kyle RA. Multiple myeloma: review of 869 cases. Mayo Clin Proc 1975; 50: 29–40.