Identification of a Neuropeptide Hormone That Regulates Sex Pheromone Production in Female Moths

American Association for the Advancement of Science (AAAS) - Tập 244 Số 4906 - Trang 796-798 - 1989
Ashok K. Raina1, Howard Jaffe1, Thomas G. Kempe2, Pamela S. Keim3, Russell Blacher3, Henry M. Fales4, Clark T. Riley5, Jerome A. Klun1, R. L. Ridgway1, D. K. Hayes1
1U. S. Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705
2Protein and Nucleic Acid Laboratory, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742.
3Applied Biosystems, Inc., Foster City, CA 94404
4National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892
5Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Tóm tắt

A pheromone biosynthesis activating neuropeptide (PBAN) hormone that controls sex pheromone production in female moths was identified from the brain-subesophageal ganglion complexes of the adult corn earworm, Heliothis zea. PBAN has 33 amino acid residues and a molecular weight of 3900. Its amino acid sequence has no significant homology with any of the fully characterized peptide hormones. The synthetic peptide, at a dose of between 2 and 4 picomoles, induced production of a normal quantity of sex pheromone in ligated H. zea females. The peptide also induced pheromone production in six other species of moths, thus indicating that this or similar peptides may be responsible for the regulation of pheromone production in moths.

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Tài liệu tham khảo

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American Association for the Advancement of Science (AAAS)

Tập 244 Số 4906

796-798

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