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Liệu pháp Hydroxyurea cho mô hình chuột mắc bệnh thiếu máu hồng cầu hình liềm ức chế sự tiến triển của bệnh do phế cầu khuẩn bằng cách điều chỉnh nồng độ E-selectin
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Tài liệu tham khảo
Steinberg, 2010, The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: a 17.5 year follow-up., Am J Hematol, 85, 403
Voskaridou, 2010, The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)., Blood, 115, 2354, 10.1182/blood-2009-05-221333
Platt, 1994, Mortality in sickle cell disease. Life expectancy and risk factors for early death., N Engl J Med, 330, 1639, 10.1056/NEJM199406093302303
Charache, 1996, Hydroxyurea and sickle cell anemia. Clinical utility of a myelosuppressive “switching” agent. The Multicenter Study of Hydroxyurea in Sickle Cell Anemia., Medicine, 75, 300, 10.1097/00005792-199611000-00002
Charache, 1995, Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia., N Engl J Med, 332, 1317, 10.1056/NEJM199505183322001
Steinberg, 2003, Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment., JAMA, 289, 1645, 10.1001/jama.289.13.1645
Wang, 2011, Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG)., Lancet, 377, 1663, 10.1016/S0140-6736(11)60355-3
Overturf, 1999, Infections and immunizations of children with sickle cell disease., Adv Pediatr Infect Dis, 14, 191
Zarkowsky, 1986, Bacteremia in sickle hemoglobinopathies., J Pediatr, 109, 579, 10.1016/S0022-3476(86)80216-5
Gill, 1995, Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative Study of Sickle Cell Disease., Blood, 86, 776, 10.1182/blood.V86.2.776.bloodjournal862776
Miller, 2007, Hypersusceptibility to invasive pneumococcal infection in experimental sickle cell disease involves platelet-activating factor receptor., J Infect Dis, 195, 581, 10.1086/510626
McCavit, 2011, Increase in invasive streptococcus pneumoniae infections in children with sickle cell disease since pneumococcal conjugate vaccine licensure., J Pediatr, 158, 505, 10.1016/j.jpeds.2010.11.025
Cundell, 1995, Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor., Nature, 377, 435, 10.1038/377435a0
Rosch, 2010, Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease., J Clin Invest, 120, 627, 10.1172/JCI39843
Lebensburger, 2010, Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model., Haematologica, 95, 1599, 10.3324/haematol.2010.023325
Pestina, 2009, Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin., Mol Ther, 17, 245, 10.1038/mt.2008.259
Persons, 2003, The degree of phenotypic correction of murine beta thalassemia intermedia following lentiviral-mediated transfer of human gamma-globulin gene is influenced by chromosomal position effects and vector copy number., Blood, 101, 2175, 10.1182/blood-2002-07-2211
Llewellyn, 2009, Nuclear staining with alum hematoxylin., Biotech Histochem, 84, 159, 10.1080/10520290903052899
Fillon, 2006, Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology., J Immunol, 177, 6182, 10.4049/jimmunol.177.9.6182
Orihuela, 2009, Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models., J Clin Invest, 119, 1638, 10.1172/JCI36759
Garrison, 2010, The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis., PLoS Pathog, 6, e1001240, 10.1371/journal.ppat.1001240
Earls, 2010, Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome., J Neurosci, 30, 15843, 10.1523/JNEUROSCI.1425-10.2010
Richardson, 2009, Connectivity patterns revealed by mapping of active inputs on dendrites of thalamorecipient neurons in the auditory cortex., J Neurosci, 29, 6406, 10.1523/JNEUROSCI.0258-09.2009
Rosch, 2009, Calcium efflux is essential for bacterial survival in the eukaryotic host., Mol Microbiol, 72, 12, 10.1111/j.1365-2958.2009.06638.x
Lacks, 1960, A study of the genetic material determining enzyme in the pneumococcus., Biochim Biophys Acta, 39, 508, 10.1016/0006-3002(60)90205-5
Orihuela, 2004, Microarray analysis of pneumococcal gene expression during invasive disease., Infect Immun, 72, 5582, 10.1128/IAI.72.10.5582-5596.2004
Orihuela, 2004, Tissue-specific contributions of pneumococcal virulence factors to pathogenesis., J Infect Dis, 190, 1661, 10.1086/424596
Heeney, 2008, Hydroxyurea for children with sickle cell disease., Pediatr Clin North Am, 55, 483, 10.1016/j.pcl.2008.02.003
Bullard, 1996, Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice., J Exp Med, 183, 2329, 10.1084/jem.183.5.2329
Munoz, 1997, Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice., J Clin Invest, 100, 2099, 10.1172/JCI119744
Holtzclaw, 2004, Enhanced pulmonary and systemic response to endotoxin in transgenic sickle mice., Am J Respir Crit Care Med, 169, 687, 10.1164/rccm.200302-224OC
Lammers, 2011, Enhanced vulnerability for Streptococcus pneumoniae sepsis during asplenia is determined by the bacterial capsule., Immunobiology, 216, 863, 10.1016/j.imbio.2011.02.004
Hankins, 2008, Preservation of spleen and brain function in children with sickle cell anemia treated with hydroxyurea., Pediatr Blood Cancer, 50, 293, 10.1002/pbc.21271
Kaul, 2004, Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice., Am J Physiol Heart Circ Physiol, 287, H293, 10.1152/ajpheart.01150.2003
Kaul, 2006, Robust vascular protective effect of hydroxamic acid derivatives in a sickle mouse model of inflammation., Microcirculation, 13, 489, 10.1080/10739680600778456
Kinney, 1999, Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group., Blood, 94, 1550
Wang, 2001, A two-year pilot trial of hydroxyurea in very young children with sickle-cell anemia., J Pediatr, 139, 790, 10.1067/mpd.2001.119590
Karlström, 2009, Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza., J Infect Dis, 199, 311, 10.1086/596051
Johnston, 1991, Pathogenesis of pneumococcal pneumonia., Rev Infect Dis, 13, S509, 10.1093/clinids/13.Supplement_6.S509
Kanavaki, 2012, Adhesion molecules and high-sensitivity C-reactive protein levels in patients with sickle cell beta-thalassanemia., Eur J Clin Invest, 42, 27, 10.1111/j.1365-2362.2011.02551.x
Saleh, 1998, Cytokines and soluble adhesion molecules in sickle cell anemia patients during hydroxyurea therapy., Acta Haematol, 100, 26, 10.1159/000040859
Belcher, 2000, Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion., Blood, 96, 2451, 10.1182/blood.V96.7.2451
Ware, 2010, How I use hydroxyurea to treat young patients with sickle cell anemia., Blood, 115, 5300, 10.1182/blood-2009-04-146852
Chang, 2010, GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice., Blood, 116, 1779, 10.1182/blood-2009-12-260513
Solovey, 2004, Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin., Blood, 104, 840, 10.1182/blood-2003-10-3719
Okpala, 2006, Leukocyte adhesion and the pathophysiology of sickle cell disease., Curr Opin Hematol, 13, 40, 10.1097/01.moh.0000190108.62414.06