Human urinary cells for functional wound healing with sweat gland restoration

Sumin Ji1, Laixian Zhou1, Yingying Li1, Jiangbing Xiang1, Huating Chen1, Y. Liu1, Xiaobing Fu1, Xiaoyan Sun1
1Research Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Department and 4th Medical Center, Chinese PLA General Hospital and PLA Medical College/PLA Key Laboratory of Tissue Repair and Regenerative Medicine and Beijing Key Research Laboratory of Skin Injury, Repair and Regeneration/Research Unit of Trauma Care, Tissue Repair and Regeneration, Chinese Academy of Medical Sciences, Beijing, 100048, China

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Baker LB. Physiology of sweat gland function: the roles of sweating and sweat composition in human health. Temperature (Austin). 2019;6(3):211–59.

Chen R, Zhu Z, Ji S, Geng Z, Hou Q, Sun X, et al. Sweat gland regeneration: current strategies and future opportunities. Biomaterials. 2020;255:120201.

Ji SF, Zhou LX, Sun ZF, Xiang JB, Cui SY, Li Y, et al. Small molecules facilitate single factor-mediated sweat gland cell reprogramming. Mil Med Res. 2022;9(1):13.

Zhou T, Benda C, Dunzinger S, Huang Y, Ho JC, Yang J, et al. Generation of human induced pluripotent stem cells from urine samples. Nat Protoc. 2012;7(12):2080–9.

Wang Y, Qin J, Wang S, Zhang W, Duan J, Zhang J, et al. Conversion of human gastric epithelial cells to multipotent endodermal progenitors using defined small molecules. Cell Stem Cell. 2016;19(4):449–61.

Huang S, Kuri P, Aubert Y, Brewster M, Li N, Farrelly O, et al. Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell. 2021;28(9):1582-96.e6.

Claudinot S, Sakabe JI, Oshima H, Gonneau C, Mitsiadis T, Littman D, et al. Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence. Nat Commun. 2020;11(1):5645.