Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers
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Takahashi, 2007, Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, 131, 861, 10.1016/j.cell.2007.11.019
Shinde, 2016, Human embryonic and induced pluripotent stem cell based toxicity testing models: future applications in new drug discovery, Curr Med Chem, 23, 3495, 10.2174/0929867323666160627113436
Shi, 2017, Induced pluripotent stem cell technology: a decade of progress, Nat Rev Drug Discov, 16, 115, 10.1038/nrd.2016.245
Ilic, 2015, Human embryonic and induced pluripotent stem cells in clinical trials, Br Med Bull, 116, 19, 10.1093/bmb/ldv045
Park, 2008, Disease-specific induced pluripotent stem cells, Cell, 134, 877, 10.1016/j.cell.2008.07.041
Ebert, 2009, Induced pluripotent stem cells from a spinal muscular atrophy patient, Nature, 457, 277, 10.1038/nature07677
Lee, 2015, Modeling familial cancer with induced pluripotent stem cells, Cell, 161, 240, 10.1016/j.cell.2015.02.045
Sances, 2016, Modeling ALS with motor neurons derived from human induced pluripotent stem cells, Nat Neurosci, 19, 542, 10.1038/nn.4273
Sareen, 2014, Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord, J Comp Neurol, 522, 2707, 10.1002/cne.23578
Kawamura, 2016, Cardiomyocytes derived from MHC-homozygous induced pluripotent stem cells exhibit reduced allogeneic immunogenicity in MHC-matched non-human primates, Stem Cell Reports, 6, 312, 10.1016/j.stemcr.2016.01.012
Tomizawa, 2016, Transcription factors and medium suitable for initiating the differentiation of human-induced pluripotent stem cells to the hepatocyte lineage, J Cell Biochem, 117, 2001, 10.1002/jcb.25494
Mandai, 2017, Autologous induced stem-cell-derived retinal cells for macular degeneration, N Engl J Med, 377, 792, 10.1056/NEJMc1706274
Baghbaderani, 2015, cGMP-manufactured human induced pluripotent stem cells are available for pre-clinical and clinical applications, Stem Cell Reports, 5, 647, 10.1016/j.stemcr.2015.08.015
Baghbaderani, 2016, Detailed characterization of human induced pluripotent stem cells manufactured for therapeutic applications, Stem Cell Rev, 12, 394, 10.1007/s12015-016-9662-8
Burridge, 2014, Chemically defined generation of human cardiomyocytes, Nat Methods, 11, 855, 10.1038/nmeth.2999
Li, 2011, Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors, Proc Natl Acad Sci U S A, 108, 8299, 10.1073/pnas.1014041108
Ring, 2003, Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo, Diabetes, 52, 588, 10.2337/diabetes.52.3.588
Tojo, 2005, The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta, Cancer Sci, 96, 791, 10.1111/j.1349-7006.2005.00103.x
D’Amour, 2005, Efficient differentiation of human embryonic stem cells to definitive endoderm, Nat Biotechnol, 23, 1534, 10.1038/nbt1163
Sekine, 2012, Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells, Transplant Proc, 44, 1127, 10.1016/j.transproceed.2012.03.001
Kubo, 2004, Development of definitive endoderm from embryonic stem cells in culture, Development, 131, 1651, 10.1242/dev.01044
Tran, 2012, Efficient differentiation of human pluripotent stem cells into mesenchymal stem cells by modulating intracellular signaling pathways in a feeder/serum-free system, Stem Cells Dev, 21, 1165, 10.1089/scd.2011.0346
Gurdon, 1994, Activin signalling and response to a morphogen gradient, Nature, 371, 487, 10.1038/371487a0
McLean, 2007, Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed, Stem Cells, 25, 29, 10.1634/stemcells.2006-0219
Crook, 2007, The generation of six clinical-grade human embryonic stem cell lines, Cell Stem Cell, 1, 490, 10.1016/j.stem.2007.10.004
Tannenbaum, 2012, Derivation of xeno-free and GMP-grade human embryonic stem cells – platforms for future clinical applications, PLoS One, 7, e35325, 10.1371/journal.pone.0035325
Wiley, 2016, cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness, Sci Rep, 6, 30742, 10.1038/srep30742
Riolobos, 2013, HLA engineering of human pluripotent stem cells, Mol Ther, 21, 1232, 10.1038/mt.2013.59
Turner, 2013, Toward the development of a global induced pluripotent stem cell library, Cell Stem Cell, 13, 382, 10.1016/j.stem.2013.08.003
Stacey, 2013, Banking human induced pluripotent stem cells: lessons learned from embryonic stem cells?, Cell Stem Cell, 13, 385, 10.1016/j.stem.2013.09.007
Lian, 2013, Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/beta-catenin signaling under fully defined conditions, Nat Protoc, 8, 162, 10.1038/nprot.2012.150
Wilson, 2015, Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells, Fluids Barriers CNS, 12, 13, 10.1186/s12987-015-0007-9
Tohyama, 2017, Efficient large-scale 2D culture system for human induced pluripotent stem cells and differentiated cardiomyocytes, Stem Cell Rep, 9, 1406, 10.1016/j.stemcr.2017.08.025
Kirkeby, 2012, Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions, Cell Rep, 1, 703, 10.1016/j.celrep.2012.04.009
Nicoleau, 2013, Embryonic stem cells neural differentiation qualifies the role of Wnt/beta-Catenin signals in human telencephalic specification and regionalization, Stem Cells, 31, 1763, 10.1002/stem.1462
Swistowski, 2010, Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions, Stem Cells, 28, 1893, 10.1002/stem.499
Momcilovic, 2014, Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells, Stem Cells Dev, 23, 406, 10.1089/scd.2013.0412
Efthymiou, 2015, Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signaling, Stem Cells Transl Med, 4, 230, 10.5966/sctm.2014-0127
Shaltouki, 2015, Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines, Stem Cell Reports, 4, 847, 10.1016/j.stemcr.2015.02.019
Momcilovic, 2016, Derivation, characterization, and neural differentiation of integration-free induced pluripotent stem cell lines from Parkinson’s disease patients carrying SNCA, LRRK2, PARK2, and GBA mutations, PLoS One, 11, e0154890, 10.1371/journal.pone.0154890
Pei, 2016, Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes, Brain Res, 1638, 57, 10.1016/j.brainres.2015.07.048
Peng, 2014, Survival and engraftment of dopaminergic neurons manufactured by a good manufacturing practice-compatible process, Cytotherapy, 16, 1305, 10.1016/j.jcyt.2014.06.002
Ahmadian Baghbaderani, 2016, A newly defined and xeno-free culture medium supports every-other-day medium replacement in the generation and long-term cultivation of human pluripotent stem cells, PLoS One, 11, e0161229, 10.1371/journal.pone.0161229
Bar-Nur, 2011, Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells, Cell Stem Cell, 9, 17, 10.1016/j.stem.2011.06.007
Kim, 2011, Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells, Nat Biotechnol, 29, 1117, 10.1038/nbt.2052
Ohi, 2011, Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells, Nat Cell Biol, 13, 541, 10.1038/ncb2239
Lohle, 2012, Differentiation efficiency of induced pluripotent stem cells depends on the number of reprogramming factors, Stem Cells, 30, 570, 10.1002/stem.1016
Hu, 2016, Effects of cellular origin on differentiation of human induced pluripotent stem cell-derived endothelial cells, JCI Insight, 1, e85558, 10.1172/jci.insight.85558
Lee, 2017, Lineage-specific differentiation is influenced by state of human pluripotency, Cell Rep, 19, 20, 10.1016/j.celrep.2017.03.036
Sanchez-Freire, 2014, Effect of human donor cell source on differentiation and function of cardiac induced pluripotent stem cells, J Am Coll Cardiol, 64, 436, 10.1016/j.jacc.2014.04.056