Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment
Tóm tắt
The accelerated growth of finfish aquaculture has resulted in a series of developments detrimental to the environment and human health. The latter is illustrated by the widespread and unrestricted use of prophylactic antibiotics in this industry, especially in developing countries, to forestall bacterial infections resulting from sanitary shortcomings in fish rearing. The use of a wide variety of antibiotics in large amounts, including non‐biodegradable antibiotics useful in human medicine, ensures that they remain in the aquatic environment, exerting their selective pressure for long periods of time. This process has resulted in the emergence of antibiotic‐resistant bacteria in aquaculture environments, in the increase of antibiotic resistance in fish pathogens, in the transfer of these resistance determinants to bacteria of land animals and to human pathogens, and in alterations of the bacterial flora both in sediments and in the water column. The use of large amounts of antibiotics that have to be mixed with fish food also creates problems for industrial health and increases the opportunities for the presence of residual antibiotics in fish meat and fish products. Thus, it appears that global efforts are needed to promote more judicious use of prophylactic antibiotics in aquaculture as accumulating evidence indicates that unrestricted use is detrimental to fish, terrestrial animals, and human health and the environment.
Từ khóa
Tài liệu tham khảo
Angulo F.J., 2000, Antimicrobial agents in aquaculture: potential impact on health, APUA Newsletter, 18, 1
Bolton L.F., 1999, Detection of multidrug‐resistant Salmonella enterica serotype Typhimurium DT104 based on a gene which confers cross‐resistance to florfenicol and chloramphenicol, J Clin Microbiol, 37, 1348, 10.1128/JCM.37.5.1348-1351.1999
Bravo S. Dolz H. Silva M.T. Lagos C. Millanao A. andUrbina M.(2005) Informe Final. Diagnostico del uso de fármacos y otros productos químicos en la acuicultura. Universidad Austral de Chile. Facultad de Pesquerias y Oceanografia Instituto de Acuicultura. Casilla 1327. Puerto Montt Chile. Proyecto No. 2003‐28.
Bushman F., 2002, Lateral DNA Transfer. Mechanisms and Consequences., 27
Bushman F., 2002, Lateral DNA Transfer. Mechanisms and Consequences., 73
Cabello F.C.(2003) Antibiotics and aquaculture. An analysis of their potential impact upon the environment human and animal health in Chile. Fundacion Terram. Analisis de Politicas Publicas No. 17 pp. 1–16. URLhttp://www.terram.cl/docs/App17_Antibioticos_y_Acuicultura.pdf
Davies J.E. Roberts M.C. Levy S.B. Miller G.H. O’Brien T.F. andTenover F.C.(eds) (1999)Antimicrobial resistance: An ecological perspective. (A report from the American Academy of Microbiology) Colloquium held 16–18 July 1999 San Juan Puerto Rico. Washington DC USA:American Academy of Microbiology.
Furushita M., 2005, Abstracts, Joint Meeting of the 3 Divisions of the International Union of Microbiological Societies 2005. International Congress of Bacteriology and Applied Microbiology
Goldburg R.J., 2001, Marine Aquaculture in the United States: Environmental Impacts and Policy Options.
Hunter‐Cevera J. Karl D. andBuckley M.(eds) (2005) Marine microbial diversity: the key to earth’s habitability. (A report from the American Academy of Microbiology) Colloquium held 8–10 April 2005 San Francisco CA USA:Marine Microbial Diversity.Washington DC USA:American Academy of Microbiology.
Markestad A., 1997, Reduction of antibacterial drug use in Norwegian fish farming due to vaccination, Fish Vaccinol, 90, 365
Sørum H., 2000, Farming of Atlantic salmon – an experience from Norway, Acta Vet Scand, 129
Sørum H., 2006, Antimicrobial Resistance in Bacteria of Animal Origin., 213