Head Growth and Intelligence from Birth to Adulthood in Very Preterm and Term Born Individuals

Journal of the International Neuropsychological Society - Tập 25 Số 1 - Trang 48-56 - 2019
Julia Jaekel1,2, Christian Sorg3,4,5, J. Baeuml3,4,5, Peter Bartmann6, Dieter Wolke2,7
1Department of Child and Family Studies, University of Tennessee, Knoxville, Tennessee
2Department of Psychology, University of Warwick, Coventry, United Kingdom
3Department of Neuroradiology Technische Universität München TUM, Munich, Germany
4Department of Psychiatry of Klinikum rechts der Isar, Technische Universität München TUM, Munich, Germany
5TUM-Neuroimaging Center Technische Universität München TUM, Munich, Germany
6Department of Neonatology, University Hospital Bonn, Bonn, Germany
7Division of Mental Health and Wellbeing, Warwick Medical School, University of Warwick, Coventry, United Kingdom

Tóm tắt

AbstractObjectives:The aim of this study was to investigate the effects of infant and toddler head growth on intelligence scores from early childhood to adulthood in very preterm (<32 weeks gestational age; VP) and/or very low birth weight (<1500 g; VLBW) and term born individuals.Methods:203 VP/VLBW and 198 term comparisons were studied from birth to adulthood as part of the prospective geographically defined Bavarian Longitudinal Study (BLS). Head circumference was assessed at birth; 5, 20 months; and 4 years of age. Intelligence was assessed with standardized tests in childhood (6 and 8 years: K-ABC) and at 26 years (Wechsler Adult Intelligence Scale, WAIS). Structural equation modeling (SEM) was used to model the effect of head growth on IQ.Results:On average, VP/VLBW had lower head circumference at birth (27.61 cmvs. 35.11 cm, mean difference 7.49, 95% confidence interval [7.09–7.90]) and lower adult intelligence scores (88.98vs. 102.54, mean difference 13.56 [10.59–16.53]) than term born comparison individuals. Head circumference at birth (e.g., total effect β=.48;p<.001 for adult IQ) and head growth in childhood predicted intelligence development from age 6 to 26 years in both VP/VLBW and term born individuals (70% of variance in adult IQ explained by full model). Effects of gestation and birth weight on intelligence were fully mediated by head circumference and growth.Conclusions:This longitudinal investigation from birth to adulthood indicates head growth as a proxy of brain development and intelligence. Repeated early head circumference assessment adds valuable information when screening for long-term neurocognitive risk. (JINS, 2019, 25, 48#x2013;56)

Từ khóa


Tài liệu tham khảo

Garcia-Alix, 2004, [Ability of neonatal head circumference to predict long-term neurodevelopmental outcome], Revista de Neurologia, 39, 548

10.1038/pr.2014.171

10.1126/science.1209459

10.1093/cercor/bhu133

10.1186/1471-2393-13-S1-S10

10.1542/peds.2017-4058

10.1001/jamaneurol.2014.1638

10.1055/s-2008-1026596

10.1016/j.jpeds.2013.08.047

10.1093/brain/awn062

10.1017/S0012162299000201

10.1136/archdischild-2017-313102

10.1016/j.neuroimage.2015.10.047

10.1016/j.jadohealth.2013.06.014

10.1523/JNEUROSCI.3976-13.2014

Doyle, 2014, BMC Pediatrics, 14, 279

10.1080/87565641003696833

10.1055/s-2002-36735

10.1542/peds.2016-4086

10.1111/apa.13669

Melchers, 1991, K-ABC: Kaufman Battery for Children: Deutschsprachige Fassung

10.1371/journal.pone.0065219

10.1542/peds.2013-2336

10.1111/jpc.12475

Kiesler, 2003, The abnormal fontanel, American Family Physician, 67, 2547

10.1371/journal.pmed.0030265

Sameroff, 1987, Intelligence quotient scores of 4-year-old children: Social-environmental risk factors, Pediatrics, 79, 343, 10.1542/peds.79.3.343

Bauer, 1988, Ein Verfahren zur Messung des fuer das Bildungsverhalten relevanten Sozial Status (BRSS) - ueberarbeitete Fassung

10.1186/1471-2431-13-59

Von Aster, 2006, Wechsler Intelligenztest für Erwachsene (WIE) [Wechsler Adult Intelligence Scale (WAIS III)]

10.1542/peds.2014-3172

10.1111/j.1467-8624.2012.01849.x

10.1016/j.jpeds.2017.04.059

10.1016/j.tics.2005.01.003

10.1093/cercor/bhr176

10.1016/j.jpeds.2016.06.045

10.1542/peds.2015-0608

10.1542/peds.2007-2671

10.1136/adc.2005.077818

10.1111/jcpp.12358

10.1542/peds.2005-2629

10.1542/peds.2005-0173

Jaekel, 2011, Parental bookreading as a resource for pre-schoolers´ cognitive skills in Turkish migrant and German non-migrant families, International Journal of Developmental Science, 5, 1

10.3171/2014.12.PEDS14251

10.1016/j.intell.2014.02.006

10.1542/peds.2005-1316

10.1007/s00429-015-1032-9

10.1203/PDR.0b013e3181cb8e2f

10.1542/peds.2005-0682

10.1136/bmj.e7961

10.1093/cercor/bht431

10.1093/cercor/bhu027

10.1080/10705511.2016.1266267

10.1038/pr.2016.276

10.1016/j.jpeds.2014.08.028

10.1016/j.lindif.2014.02.001

10.1007/s10519-011-9521-y

Brandt, 1983, Griffiths Entwicklungsskalen (GES zur Beurteilung der Entwicklung in den ersten beiden Lebensjahren)

WHO. (2007). WHO Child Growth Standards: Head circumference-for-age, arm circumference-for-age, triceps skinfold-for-age and subscapular skinfold-for-age: Methods and development. Retrieved from http://www.who.int/childgrowth/publications/en

10.1016/j.jpeds.2015.02.065

10.1093/aje/kwp132

Thông tin
Thông tin xuất bản

Journal of the International Neuropsychological Society

Tập 25 Số 1

48-56

Thông tin tác giả