HIERARCHY AND DYNAMICS OF RNA FOLDING

Annual Reviews - Tập 26 Số 1 - Trang 113-137 - 1997
Philippe Brion1, Éric Westhof1
1Institut de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, UPR 9002 15 rue Descartes, Strasbourg, 67084 France;

Tóm tắt

▪ Abstract  The evidence showing that the self-assembly of complex RNAs occurs in discrete transitions, each relating to the folding of sub-systems of increasing size and complexity starting from a state with most of the secondary structure, is reviewed. The reciprocal influence of the concentration of magnesium ions and nucleotide mutations on tertiary structure is analyzed. Several observations demonstrate that detrimental mutations can be rescued by high magnesium concentrations, while stabilizing mutations lead to a lesser dependence on magnesium ion concentration. Recent data point to the central controlling and monitoring roles of RNA-binding proteins that can bind to the different folding stages, either before full establishment of the secondary structure or at the molten globule state before the cooperative transition to the final three-dimensional structure.

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Tài liệu tham khảo

10.1093/nar/19.21.5901

10.1093/nar/20.4.819

10.1016/S0968-0004(00)89039-8

Deleted in proof

10.1021/bi00052a021

10.1021/bi00019a031

10.1021/bi00479a027

10.1021/bi960870m

10.1021/bi00273a005

10.1016/0022-2836(80)90051-0

10.1021/bi00279a014

10.1007/978-3-642-78666-2_5

10.1016/S0092-8674(00)81807-3

10.1006/jmbi.1996.0182

Cech TR, Herschlag D. 1996.Group I ribozymes: substrate recognition, catalytic strategies, and comparative mechanistic analysis.InNucleic Acids and Molecular Biology, ed. F Eckstein, DMJ Lilley, 10:1–17. Berlin: Springer-Verlag

10.1126/science.1989074

10.1101/gad.8.13.1575

10.1021/bi00773a024

10.1002/j.1460-2075.1995.tb07111.x

10.1021/bi00716a019

10.1016/0022-2836(74)90560-9

Doudna JA, 1995, RNA, 1, 36

10.1038/nsb0596-397

10.1016/0092-8674(95)90218-X

10.1021/bi00213a040

10.1073/pnas.91.21.9675

10.1038/nsb0195-10a

10.1021/bi00203a029

10.1101/SQB.1966.031.01.068

10.1101/gad.5.10.1870

10.1006/jmbi.1994.1493

Gopalan V, Talbot SJ, Altman S. 1994.RNA-protein interactions in RNAse P.InRNA-Protein Interactions, ed. K Nagai, IW Mattaj, pp. 103–26. Oxford: IRL Press, Oxford Univ. Press

10.1006/jmbi.1995.0275

Groeneveld H, 1995, RNA, 1, 79

10.1016/S0006-3495(82)84553-0

10.1006/jmbi.1995.0356

10.1101/gad.6.8.1357

10.1002/bip.1977.360160714

10.1074/jbc.270.36.20871

10.1002/j.1460-2075.1994.tb06586.x

10.1039/ft9959102531

10.1021/bi00654a013

10.1016/0022-2836(90)90275-Q

10.1016/0022-2836(92)90557-Z

10.1016/0076-6879(90)83019-6

10.1016/0022-2836(94)90055-8

10.1007/978-3-642-61202-2_3

10.1016/0022-2836(91)90925-V

10.1006/jmbi.1993.1590

10.1093/nar/17.19.7879

10.1002/prot.340060202

10.1093/nar/9.19.5109

10.1093/nar/18.13.3803

10.1002/j.1460-2075.1994.tb06557.x

10.1006/jmbi.1994.1255

10.1006/jmbi.1994.1256

10.1016/0968-0004(90)90283-H

LeCuyer KA, 1993, Trends Biochem. Sci., 32, 5301

10.1073/pnas.91.8.3373

Levinthal C, 1968, J. Chem. Phys., 65, 44

10.1016/S0959-440X(96)80046-7

10.1006/jmbi.1994.1753

10.1111/j.1365-2958.1994.tb01337.x

10.1126/science.7539549

McGraw P, 1983, J. Biol. Chem., 258, 9459, 10.1016/S0021-9258(17)44690-4

10.1038/347578a0

10.1101/gad.6.8.1373

10.1016/0022-2836(90)90386-Z

10.1038/370147a0

10.1016/0092-8674(92)90449-M

10.1093/nar/23.15.3056

10.1021/bi00071a003

10.1006/jmbi.1994.1117

10.1126/science.8085157

10.1006/jmbi.1996.0391

10.1021/bi00003a024

Pan T, Long DM, Uhlenbeck OC. 1993.Divalent metal ions in RNA folding and catalysis.InRNA World, ed. RF Gesteland, JF Atkins, pp. 271–302. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press

10.1038/372068a0

10.1038/372111a0

10.1007/978-3-642-81117-3_5

10.1016/0022-2836(78)90421-7

10.1016/S0968-0004(00)89081-7

10.1021/bi00175a047

10.1021/bi9527348

10.1016/0022-2836(73)90388-4

10.1002/j.1460-2075.1996.tb00642.x

10.1111/j.1432-1033.1977.tb11930.x

10.1126/science.1373521

10.1016/S0092-8674(05)80004-2

10.1016/0076-6879(95)59047-1

10.1074/jbc.270.37.21552

10.1093/nar/17.14.5665

10.1096/fasebj.9.11.7544309

10.1021/bi00646a024

10.1021/bi00646a025

Tanner MA, 1996, RNA, 2, 74

10.1016/S0960-9822(00)00109-3

10.1021/ar9500933

10.1007/978-3-642-61202-2_10

10.1073/pnas.85.5.1364

10.1146/annurev.bb.17.060188.001123

Uhlenbeck OC, 1995, RNA, 1, 4

10.1073/pnas.88.1.184

10.1002/j.1460-2075.1993.tb06163.x

10.1021/bi00498a022

10.1021/bi00023a020

10.1016/0092-8674(95)90309-7

10.1126/science.271.5247.345

10.1016/0959-440X(92)90221-R

Westhof E, Michel F. 1994.Prediction and experimental investigation of RNA secondary and tertiary foldings.InRNA-Protein Interactions, ed. K Nagai, IW Mattaj, pp. 25–51. Oxford: IRL Press, Oxford Univ. Press

10.1016/0022-2836(85)90048-8

10.1073/pnas.87.21.8467

10.1126/science.7886447

10.1021/bi00222a006

10.1128/MCB.13.2.1137

10.1016/0022-2836(90)90193-P

Wyatt JR, Tinoco IJr . 1993.RNA structural elements.InRNA World, ed. RF Gesteland, JF Atkins, pp. 465–97. Cold Spring Harbor, NY: Cold Spring Harbor Lab. Press

10.1126/science.8052848

10.1093/nar/24.5.854

10.1038/nsb0596-432

Zhang A, 1995, RNA, 1, 783

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Annual Reviews

Tập 26 Số 1

113-137

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